PMID- 33182229 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230705 IS - 2076-2615 (Print) IS - 2076-2615 (Electronic) IS - 2076-2615 (Linking) VI - 10 IP - 11 DP - 2020 Nov 9 TI - Comparison of Hematological and Biochemical Results Derived from Arterial and Venous Blood Samples in Post-Anesthetic Dogs. LID - 10.3390/ani10112069 [doi] LID - 2069 AB - Collecting blood from an indwelling arterial catheter may reduce stress from repeated venipuncture in patients requiring serial monitoring, but the use of arterial blood for hematological and biochemical testing remains understudied. Here, we compared hematological and biochemical results of arterial and venous blood and evaluated their clinical interchangeability. Blood samples from dogs who had recovered from anesthesia, collected by both arterial catheterization and venipuncture, were analyzed. To assess clinical acceptance between paired samples, the limit of agreement between the values derived from the arterial and venous blood samples was compared with the allowable total error (TEa) recommended for each parameter. We found no significant differences between the arterial and venous sample results for red/white blood cell and platelet counts and hematocrit, blood urea nitrogen, phosphate, total protein, albumin, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transpeptidase, total bilirubin, sodium, potassium, and chloride levels, whereas hemoglobin, glucose, creatinine, and calcium levels differed significantly (p < 0.05). Moreover, only gamma-glutamyl transpeptidase and potassium exceeded the recommended TEa. Hematological and biochemical results derived from venous and arterial blood samples are clinically interchangeable in post-anesthetic dogs, with the exception of gamma-glutamyl transpeptidase and potassium; thus, these values should be used with caution. FAU - Lee, Song Mi AU - Lee SM AD - Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea. FAU - Kang, Byung-Jae AU - Kang BJ AUID- ORCID: 0000-0002-2419-1775 AD - Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea. FAU - Lee, Sungin AU - Lee S AUID- ORCID: 0000-0003-4976-7467 AD - Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea. FAU - Kim, Wan Hee AU - Kim WH AD - Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea. LA - eng GR - PJ01499001/the Cooperative Research Program of Center for Companion Animal Research, Rural Development Administration/ PT - Journal Article DEP - 20201109 PL - Switzerland TA - Animals (Basel) JT - Animals : an open access journal from MDPI JID - 101635614 CIN - Int J Lab Hematol. 2023 Jun;45(3):e90-e92. PMID: 36627166 PMC - PMC7695303 OTO - NOTNLM OT - arterial OT - biochemical OT - dog OT - hematological OT - interchangeability OT - venous COIS- The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results. EDAT- 2020/11/14 06:00 MHDA- 2020/11/14 06:01 PMCR- 2020/11/09 CRDT- 2020/11/13 01:02 PHST- 2020/10/15 00:00 [received] PHST- 2020/11/03 00:00 [accepted] PHST- 2020/11/13 01:02 [entrez] PHST- 2020/11/14 06:00 [pubmed] PHST- 2020/11/14 06:01 [medline] PHST- 2020/11/09 00:00 [pmc-release] AID - ani10112069 [pii] AID - animals-10-02069 [pii] AID - 10.3390/ani10112069 [doi] PST - epublish SO - Animals (Basel). 2020 Nov 9;10(11):2069. doi: 10.3390/ani10112069.