PMID- 33183832
OWN - NLM
STAT- MEDLINE
DCOM- 20210721
LR  - 20210721
IS  - 1535-6280 (Electronic)
IS  - 0146-2806 (Linking)
VI  - 46
IP  - 3
DP  - 2021 Mar
TI  - Toxoplasmosis and the Heart.
PG  - 100741
LID - S0146-2806(20)30217-6 [pii]
LID - 10.1016/j.cpcardiol.2020.100741 [doi]
AB  - Toxoplasmosis is a common disease caused by Toxoplasma gondii, a parasite with 
      high prevalence in tropical regions. Most infections show minimal symptoms, but 
      immunocompromised patients tend to have a poor prognosis. Cardiovascular 
      manifestations in toxoplasmosis are rare and reported in a limited number of 
      patients. As part of the "Neglected Tropical Diseases and Other Infectious 
      Diseases Affecting the Heart" (NET-Heart) project, this paper aims to 
      systematically review all available information regarding the cardiovascular 
      implications of toxoplasmosis. Relevant studies were identified in the MEDLINE 
      and/or PubMed database, and 48 articles were ultimately included. This was 
      completed according to the Preferred Reporting Items for Systematic Reviews and 
      Meta-analyses guidelines. Cardiac compromise in toxoplasmosis mainly involves 
      myocarditis, and complications vary widely in severity. Toxoplasmic myocarditis 
      is challenging to diagnose, as endomyocardial biopsy is usually required. This 
      article provides a summary of cardiac toxoplasmosis, including an original 
      algorithm facilitating diagnosis and treatment.
CI  - Copyright (c) 2020 Elsevier Inc. All rights reserved.
FAU - Zhou, Zier
AU  - Zhou Z
AD  - Division of Cardiology, Kingston Health Sciences Centre, Queen's University, 
      Kingston, Ontario, Canada.
FAU - Ortiz Lopez, Hector Isaac Alejandro
AU  - Ortiz Lopez HIA
AD  - Division of Cardiology, Hospital Herrera Llerandi, Guatemala City, Guatemala.
FAU - Perez, Gonzalo Emanuel
AU  - Perez GE
AD  - Division of Cardiology, Clinica Olivos, Buenos Aires, Argentina.
FAU - Burgos, Lucrecia Maria
AU  - Burgos LM
AD  - Department of Heart Failure, Pulmonary Hypertension and Heart Transplant, 
      Instituto Cardiovascular de Buenos Aires, Buenos Aires, Argentina.
FAU - Farina, Juan Maria
AU  - Farina JM
AD  - Division of Cardiology, Clinica Olivos, Buenos Aires, Argentina.
FAU - Saldarriaga, Clara
AU  - Saldarriaga C
AD  - Department of Cardiology and Heart Failure Clinic, Cardiovascular Clinic Santa 
      Maria, University of Antioquia, Medellin, Colombia.
FAU - Lopez-Santi, Ricardo
AU  - Lopez-Santi R
AD  - Division of Cardiology, Hospital Italiano de La Plata, Buenos Aires, Argentina.
FAU - Cotella, Juan Ignacio
AU  - Cotella JI
AD  - Division of Cardiology, Centro Privado de Cardiologia San Miguel de Tucuman, 
      Tucuman, Argentina.
FAU - Perez, Ana Laura Sauce
AU  - Perez ALS
AD  - Division of Cardiology, Centro Medico Nacional Siglo XXI, Mexico City, Mexico.
FAU - Baranchuk, Adrian
AU  - Baranchuk A
AD  - Division of Cardiology, Kingston Health Sciences Centre, Queen's University, 
      Kingston, Ontario, Canada. Electronic address: Adrian.Baranchuk@kingstonhsc.ca.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20201102
PL  - Netherlands
TA  - Curr Probl Cardiol
JT  - Current problems in cardiology
JID - 7701802
SB  - IM
MH  - Humans
MH  - *Myocarditis/diagnosis/epidemiology/parasitology
MH  - Prevalence
MH  - *Toxoplasma
MH  - *Toxoplasmosis/complications/diagnosis/epidemiology
EDAT- 2020/11/14 06:00
MHDA- 2021/07/22 06:00
CRDT- 2020/11/13 05:37
PHST- 2020/10/03 00:00 [received]
PHST- 2020/10/04 00:00 [accepted]
PHST- 2020/11/14 06:00 [pubmed]
PHST- 2021/07/22 06:00 [medline]
PHST- 2020/11/13 05:37 [entrez]
AID - S0146-2806(20)30217-6 [pii]
AID - 10.1016/j.cpcardiol.2020.100741 [doi]
PST - ppublish
SO  - Curr Probl Cardiol. 2021 Mar;46(3):100741. doi: 10.1016/j.cpcardiol.2020.100741. 
      Epub 2020 Nov 2.