PMID- 33189216
OWN - NLM
STAT- MEDLINE
DCOM- 20210511
LR  - 20210511
IS  - 2213-3763 (Electronic)
IS  - 0019-4832 (Print)
IS  - 0019-4832 (Linking)
VI  - 72
IP  - 5
DP  - 2020 Sep-Oct
TI  - Post-the SAFARI STEMI study: Is there still a debate on radial vs. femoral access 
      in STEMI?
PG  - 466-468
LID - S0019-4832(20)30190-5 [pii]
LID - 10.1016/j.ihj.2020.08.006 [doi]
AB  - Despite the seminal trials on radial versus femoral access for percutaneous 
      coronary intervention (PCI) in ST elevation myocardial infarction (STEMI) showing 
      reduced bleeding, major adverse cardiovascular events and mortality; these 
      outcomes were attributed by some to low usage of bivalirudin and an unnecessarily 
      higher dose of Heparin, combined with high usage of GP IIb/IIIa inhibitors, as 
      well as to the use of larger bore catheters in the femoral groups. To prove the 
      point, a study comparing TF with TR access was mooted( Lee et al., 2013) 3; with 
      bivalirudin instead of heparin, preferably with use of potent oral anti-platelets 
      instead of GP IIb/IIIa inhibitors; and femoral vascular closure devices, 
      ostensibly, to assess outcomes based on 'access-site alone'. With this intent, 
      the SAFARI STEMI study was designed. In this article we discuss some of the major 
      short-comings of this trial which raise significant questions on its results.
CI  - Copyright (c) 2020 Cardiological Society of India. Published by Elsevier B.V. All 
      rights reserved.
FAU - Chugh, Yashasvi
AU  - Chugh Y
AD  - Interventional Cardiology, Minneapolis Heart Institute, Abbott Northwestern 
      Hospital, Minneapolis, USA. Electronic address: yashasvichugh@gmail.com.
FAU - Chugh, Sunita
AU  - Chugh S
AD  - Non-invasive Cardiology, Jaipur National University Hospital and Medical College, 
      Institute for Medical Sciences and Research Center, Jaipur, Rajasthan, India. 
      Electronic address: sunitachugh@yahoo.com.
FAU - Chugh, Sanjay Kumar
AU  - Chugh SK
AD  - Department of Cardiology and Interventional Cardiology, Jaipur National 
      University Hospital and Medical College, Institute for Medical Sciences and 
      Research Center, Jaipur, Rajasthan, India. Electronic address: 
      skchughcardiology@yahoo.com.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20200813
PL  - India
TA  - Indian Heart J
JT  - Indian heart journal
JID - 0374675
SB  - IM
MH  - Cardiac Catheterization/*methods
MH  - *Decision Making
MH  - Femoral Artery
MH  - Humans
MH  - Percutaneous Coronary Intervention/*methods
MH  - Radial Artery
MH  - ST Elevation Myocardial Infarction/*surgery
PMC - PMC7670265
OTO - NOTNLM
OT  - Femoral access
OT  - Primary angioplasty
OT  - STEMI
OT  - Transradial access
COIS- Declaration of competing interest All authors have none to declare.
EDAT- 2020/11/16 06:00
MHDA- 2021/05/12 06:00
PMCR- 2020/09/01
CRDT- 2020/11/15 20:19
PHST- 2020/02/12 00:00 [received]
PHST- 2020/06/24 00:00 [revised]
PHST- 2020/08/03 00:00 [accepted]
PHST- 2020/11/15 20:19 [entrez]
PHST- 2020/11/16 06:00 [pubmed]
PHST- 2021/05/12 06:00 [medline]
PHST- 2020/09/01 00:00 [pmc-release]
AID - S0019-4832(20)30190-5 [pii]
AID - 10.1016/j.ihj.2020.08.006 [doi]
PST - ppublish
SO  - Indian Heart J. 2020 Sep-Oct;72(5):466-468. doi: 10.1016/j.ihj.2020.08.006. Epub 
      2020 Aug 13.