PMID- 33190197
OWN - NLM
STAT- MEDLINE
DCOM- 20210510
LR  - 20210510
IS  - 1590-3478 (Electronic)
IS  - 1590-1874 (Linking)
VI  - 42
IP  - 4
DP  - 2021 Apr
TI  - Anti-MOG-associated demyelinating disorders: two sides of the same coin.
PG  - 1531-1534
LID - 10.1007/s10072-020-04892-7 [doi]
AB  - BACKGROUND: Anti-myelin oligodendrocyte glycoprotein antibody-associated 
      disorders (MOGAD) are new emerging diseases with heterogeneous course, treatment, 
      response, and prognosis. CASE REPORT: We herein present 2 cases with antibodies 
      to MOG, one with a cerebellar/brainstem monophasic syndrome which partially 
      improved after treatment, and the other with an optic neuritis onset then 
      relapsed with cortical encephalitis and presented a subsequent complete recovery. 
      We further discuss elements possibly associated with disease heterogeneity and 
      influencing treatment choices. CONCLUSIONS: MOGAD is an extremely variable 
      disease which can relapse and accumulate disability over time. An early diagnosis 
      and correct timely treatment is fundamental to improve clinical outcome.
FAU - Maniscalco, Giorgia Teresa
AU  - Maniscalco GT
AUID- ORCID: 0000-0002-0679-9939
AD  - Multiple Sclerosis Center, "A. Cardarelli" Hospital, Naples, Italy. 
      gtmaniscalco@libero.it.
AD  - Neurological Clinic and Stroke Unit, "A. Cardarelli" Hospital, Naples, Italy. 
      gtmaniscalco@libero.it.
FAU - Allegorico, Lia
AU  - Allegorico L
AD  - Multiple Sclerosis Center, "A. Cardarelli" Hospital, Naples, Italy.
FAU - Alfieri, Gennaro
AU  - Alfieri G
AD  - Neurological Clinic and Stroke Unit, "A. Cardarelli" Hospital, Naples, Italy.
FAU - Napolitano, Massimo
AU  - Napolitano M
AD  - Neurological Clinic and Stroke Unit, "A. Cardarelli" Hospital, Naples, Italy.
FAU - Ranieri, Angelo
AU  - Ranieri A
AD  - Neurological Clinic and Stroke Unit, "A. Cardarelli" Hospital, Naples, Italy.
FAU - Renna, Rosaria
AU  - Renna R
AD  - Neurological Clinic and Stroke Unit, "A. Cardarelli" Hospital, Naples, Italy.
FAU - Servillo, Giovanna
AU  - Servillo G
AD  - Neurological Clinic and Stroke Unit, "A. Cardarelli" Hospital, Naples, Italy.
FAU - Pezzella, Marianna
AU  - Pezzella M
AD  - UOC Neurophysiopathology, "A. Cardarelli" Hospital, Naples, Italy.
FAU - Capone, Elisa
AU  - Capone E
AD  - Neuroradiology Department, "A. Cardarelli" Hospital, Naples, Italy.
FAU - Altomare, Lidia
AU  - Altomare L
AD  - Immunohematology and Transfusion Medicine, "A. Cardarelli" Hospital, Naples, 
      Italy.
FAU - Spiniello, Michele
AU  - Spiniello M
AD  - Immunohematology and Transfusion Medicine, "A. Cardarelli" Hospital, Naples, 
      Italy.
FAU - Ferrari, Sergio
AU  - Ferrari S
AD  - Neurology Unit, Department of Neuroscience, Biomedicine, and Movement Sciences, 
      University of Verona, Verona, Italy.
FAU - Manzo, Valentino
AU  - Manzo V
AD  - Neurological Clinic and Stroke Unit, "A. Cardarelli" Hospital, Naples, Italy.
FAU - Mariotto, Sara
AU  - Mariotto S
AD  - Neurology Unit, Department of Neuroscience, Biomedicine, and Movement Sciences, 
      University of Verona, Verona, Italy.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20201114
PL  - Italy
TA  - Neurol Sci
JT  - Neurological sciences : official journal of the Italian Neurological Society and 
      of the Italian Society of Clinical Neurophysiology
JID - 100959175
RN  - 0 (Antibodies)
RN  - 0 (Autoantibodies)
RN  - 0 (Myelin-Oligodendrocyte Glycoprotein)
SB  - IM
MH  - Antibodies
MH  - Autoantibodies
MH  - *Demyelinating Diseases/metabolism
MH  - *Encephalitis
MH  - Humans
MH  - *Myelin-Oligodendrocyte Glycoprotein
MH  - *Optic Neuritis
OTO - NOTNLM
OT  - Anti-MOG-associated disorders (MOGAD)
OT  - Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies
OT  - Demyelinating diseases
OT  - Plasma exchange
OT  - Rituximab
EDAT- 2020/11/16 06:00
MHDA- 2021/05/11 06:00
CRDT- 2020/11/15 20:36
PHST- 2020/07/13 00:00 [received]
PHST- 2020/11/07 00:00 [accepted]
PHST- 2020/11/16 06:00 [pubmed]
PHST- 2021/05/11 06:00 [medline]
PHST- 2020/11/15 20:36 [entrez]
AID - 10.1007/s10072-020-04892-7 [pii]
AID - 10.1007/s10072-020-04892-7 [doi]
PST - ppublish
SO  - Neurol Sci. 2021 Apr;42(4):1531-1534. doi: 10.1007/s10072-020-04892-7. Epub 2020 
      Nov 14.