PMID- 33191993 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220211 IS - 0970-9134 (Print) IS - 0973-7723 (Electronic) IS - 0970-9134 (Linking) VI - 37 IP - Suppl 2 DP - 2021 Apr TI - The challenges of venoarterial extracorporeal membrane oxygenation for postcardiotomy cardiogenic shock. PG - 289-293 LID - 10.1007/s12055-020-01068-y [doi] AB - Postcardiotomy cardiogenic shock describes the syndrome of refractory cardiac performance following cardiac surgery. The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) for the management of postcardiotomy cardiogenic shock is controversial, and there are at least three scenarios where it may be necessary: first, pre-emptive postoperative VA-ECMO, where the decision for postoperative mechanical support is made prior to surgery, for example, in the context of poor pre-operative cardiac function; second, early yet unplanned post-cardiopulmonary bypass VA-ECMO following a long duration of cardiopulmonary bypass due to, for example, unexpected surgical complications; third, late rescue VA-ECMO following several attempts at weaning, either immediately following cardiopulmonary bypass or following transfer to the intensive care unit. The use of mechanical circulatory support for postcardiotomy cardiogenic shock is further complicated by the wide range of available devices, the availability of VA-ECMO in different centres, variations in experience and expertise as a function of local VA-ECMO workload, and regional variations in the diagnosis and management of postcardiotomy cardiogenic shock. Furthermore, survival appears to be low for such patients and it is not yet possible to predict who will survive. Many questions remain, however, such as those in relation to practices around patient selection, how best to study long-term outcomes, the ethics and efficacy of ECMO in such patients, and on all aspects of clinical decision-making. This review sets these clinical challenges in the context of the available evidence, including that from our centre. CI - (c) Indian Association of Cardiovascular-Thoracic Surgeons 2020. FAU - Michael, Charlesworth AU - Michael C AUID- ORCID: 0000-0001-7389-4955 AD - Department of Cardiothoracic Critical Care, Anaesthesia and ECMO, Wythenshawe Hospital, Manchester, UK. GRID: grid.417286.e. ISNI: 0000 0004 0422 2524 FAU - Venkateswaran, Rajamiyer AU - Venkateswaran R AD - Department of Cardiothoracic Surgery and Transplantation, Wythenshawe Hospital, Manchester, UK. GRID: grid.417286.e. ISNI: 0000 0004 0422 2524 LA - eng PT - Journal Article DEP - 20201107 PL - India TA - Indian J Thorac Cardiovasc Surg JT - Indian journal of thoracic and cardiovascular surgery JID - 8700105 PMC - PMC7647888 OTO - NOTNLM OT - Cardiac surgery OT - Cardiogenic shock OT - ECMO OT - Postcardiotomy OT - Venoarterial extracorporeal membrane oxygenation COIS- Conflict of interestThe authors declare that they have no conflict of interest. EDAT- 2020/11/17 06:00 MHDA- 2020/11/17 06:01 PMCR- 2022/04/01 CRDT- 2020/11/16 08:42 PHST- 2020/06/22 00:00 [received] PHST- 2020/09/22 00:00 [revised] PHST- 2020/09/25 00:00 [accepted] PHST- 2020/11/17 06:00 [pubmed] PHST- 2020/11/17 06:01 [medline] PHST- 2020/11/16 08:42 [entrez] PHST- 2022/04/01 00:00 [pmc-release] AID - 1068 [pii] AID - 10.1007/s12055-020-01068-y [doi] PST - ppublish SO - Indian J Thorac Cardiovasc Surg. 2021 Apr;37(Suppl 2):289-293. doi: 10.1007/s12055-020-01068-y. Epub 2020 Nov 7.