PMID- 33196979
OWN - NLM
STAT- MEDLINE
DCOM- 20210419
LR  - 20210419
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Linking)
VI  - 31
IP  - 3
DP  - 2021 Mar
TI  - Role of DiaRem Score in Preoperative Prediction of Type 2 Diabetes Mellitus 
      Remission After Laparoscopic Roux-en-Y Gastric Bypass: Indian Perspective.
PG  - 1265-1270
LID - 10.1007/s11695-020-05129-4 [doi]
AB  - BACKGROUND: Roux-en-Y gastric bypass (RYGB) has emerged as the most effective 
      treatment in reversing insulin resistance in patients with type 2 diabetes 
      mellitus (T2DM). A number of models and statistical tools have been proposed to 
      predict patients likely to experience diabetes remission post-RYGB. The purpose 
      of our study was to evaluate the preoperative accuracy of DiaRem score in 
      predicting T2DM remission at 1 year of follow-up in a retrospective analysis of 
      diabetic morbidly obese patients who underwent RYGB. METHODS: One hundred and 
      forty-three patients underwent RYGB between January 2018 and December 2018. We 
      conducted a retrospective analysis in 55 patients (38.46%) with T2DM with 1 year 
      of follow-up. DiaRem score was calculated, and patients were stratified in five 
      groups. RESULT: At a 1-year follow-up, we found a higher proportion of patients 
      with T2DM remission in the lower score group compared to a lower proportion of 
      patients with remission in the higher score group. We derived a DiaRem cut-off 
      score of 6.5 that had high sensitivity and specificity to predict T2DM remission 
      preoperatively. We found a significant decrease in BMI and HbA1C values 
      post-operatively at 1 year following RYGB. CONCLUSION: DiaRem score is an easy to 
      determine score based on basic clinical parameters that could identify patients 
      with T2DM who would achieve maximal benefit in terms of remission after bariatric 
      surgery. The development of a suitable scoring tool would be clinically useful as 
      it would enable clinicians to better triage patients for RYGB.
FAU - Chowbey, Pradeep
AU  - Chowbey P
AD  - Minimal Access, Metabolic & Bariatric Surgery (MAMBS) Department, Max 
      Superspeciality Hospital, 1 & 2, Press Enclave Marg, Saket, New Delhi, 110017, 
      India.
FAU - Kelkar, Rajat
AU  - Kelkar R
AUID- ORCID: 0000-0001-9161-8508
AD  - Minimal Access, Metabolic & Bariatric Surgery (MAMBS) Department, Max 
      Superspeciality Hospital, 1 & 2, Press Enclave Marg, Saket, New Delhi, 110017, 
      India. rajatkelkar1@gmail.com.
FAU - Soni, Vandana
AU  - Soni V
AD  - Minimal Access, Metabolic & Bariatric Surgery (MAMBS) Department, Max 
      Superspeciality Hospital, 1 & 2, Press Enclave Marg, Saket, New Delhi, 110017, 
      India.
FAU - Khullar, Rajesh
AU  - Khullar R
AD  - Minimal Access, Metabolic & Bariatric Surgery (MAMBS) Department, Max 
      Superspeciality Hospital, 1 & 2, Press Enclave Marg, Saket, New Delhi, 110017, 
      India.
FAU - Sharma, Anil
AU  - Sharma A
AD  - Minimal Access, Metabolic & Bariatric Surgery (MAMBS) Department, Max 
      Superspeciality Hospital, 1 & 2, Press Enclave Marg, Saket, New Delhi, 110017, 
      India.
FAU - Baijal, Manish
AU  - Baijal M
AD  - Minimal Access, Metabolic & Bariatric Surgery (MAMBS) Department, Max 
      Superspeciality Hospital, 1 & 2, Press Enclave Marg, Saket, New Delhi, 110017, 
      India.
LA  - eng
PT  - Journal Article
DEP - 20201116
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
SB  - IM
MH  - *Diabetes Mellitus, Type 2/surgery
MH  - *Gastric Bypass
MH  - Humans
MH  - *Laparoscopy
MH  - *Obesity, Morbid/surgery
MH  - Remission Induction
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - DiaRem score
OT  - Roux-en-Y gastric bypass
OT  - Type 2 DM remission
EDAT- 2020/11/17 06:00
MHDA- 2021/04/20 06:00
CRDT- 2020/11/16 14:50
PHST- 2020/07/30 00:00 [received]
PHST- 2020/11/11 00:00 [accepted]
PHST- 2020/11/11 00:00 [revised]
PHST- 2020/11/17 06:00 [pubmed]
PHST- 2021/04/20 06:00 [medline]
PHST- 2020/11/16 14:50 [entrez]
AID - 10.1007/s11695-020-05129-4 [pii]
AID - 10.1007/s11695-020-05129-4 [doi]
PST - ppublish
SO  - Obes Surg. 2021 Mar;31(3):1265-1270. doi: 10.1007/s11695-020-05129-4. Epub 2020 
      Nov 16.