PMID- 33202352
OWN - NLM
STAT- MEDLINE
DCOM- 20210222
LR  - 20210222
IS  - 1878-9307 (Electronic)
IS  - 1878-9293 (Print)
IS  - 1878-9293 (Linking)
VI  - 46
DP  - 2020 Dec
TI  - Longitudinal associations between structural prefrontal cortex and nucleus 
      accumbens development and daily identity formation processes across adolescence.
PG  - 100880
LID - S1878-9293(20)30130-4 [pii]
LID - 10.1016/j.dcn.2020.100880 [doi]
LID - 100880
AB  - We tested whether adolescents with daily high identity uncertainty showed 
      differential structural brain development across adolescence and young adulthood. 
      Participants (N = 150, M(ageT1) 15.92 years) were followed across three waves, 
      covering 4 years. Self-reported daily educational identity and structural brain 
      data of lateral prefrontal cortex (lPFC)/anterior cingulate cortex (ACC), medial 
      PFC, and nucleus accumbens (NAcc) was collected across three waves. All 
      hypotheses were pre-registered. Latent class growth analyses confirmed 2 identity 
      subgroups: an identity synthesis class (characterized by strong commitments, and 
      low uncertainty), and an identity moratorium class (high daily identity 
      uncertainty). Latent growth curve models revealed, on average, delayed maturation 
      of the lateral PFC/ACC and medial PFC and stable NAcc. Yet, adolescents in 
      identity moratorium showed lower levels and less decline in NAcc gray matter 
      volume. Lateral PFC/ACC and medial PFC trajectories did not differ between 
      identity subgroups. Exploratory analyses revealed that adolescents with higher 
      baseline levels and delayed maturation of lateral PFC/ACC and medial PFC gray 
      matter volume, surface area, and cortical thickness reported higher baseline 
      levels and stronger increases of in-depth exploration. These results provide 
      insight into how individual differences in brain development relate to 
      fluctuations in educational identity development across adolescence and young 
      adulthood.
CI  - Copyright (c) 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.
FAU - Becht, Andrik I
AU  - Becht AI
AD  - Erasmus School of Social and Behavioural Sciences, Erasmus University Rotterdam, 
      The Netherlands; Research Center Adolescent Development, Utrecht University, The 
      Netherlands; Brain and Development Research Center, Leiden University, The 
      Netherlands. Electronic address: becht@essb.eur.nl.
FAU - Klapwijk, Eduard T
AU  - Klapwijk ET
AD  - Erasmus School of Social and Behavioural Sciences, Erasmus University Rotterdam, 
      The Netherlands; Brain and Development Research Center, Leiden University, The 
      Netherlands.
FAU - Wierenga, Lara M
AU  - Wierenga LM
AD  - Brain and Development Research Center, Leiden University, The Netherlands.
FAU - van der Cruijsen, Renske
AU  - van der Cruijsen R
AD  - Erasmus School of Social and Behavioural Sciences, Erasmus University Rotterdam, 
      The Netherlands.
FAU - Spaans, Jochem
AU  - Spaans J
AD  - Erasmus School of Social and Behavioural Sciences, Erasmus University Rotterdam, 
      The Netherlands.
FAU - van der Aar, Laura
AU  - van der Aar L
AD  - Erasmus School of Social and Behavioural Sciences, Erasmus University Rotterdam, 
      The Netherlands.
FAU - Peters, Sabine
AU  - Peters S
AD  - Brain and Development Research Center, Leiden University, The Netherlands.
FAU - Branje, Susan
AU  - Branje S
AD  - Research Center Adolescent Development, Utrecht University, The Netherlands.
FAU - Meeus, Wim
AU  - Meeus W
AD  - Research Center Adolescent Development, Utrecht University, The Netherlands.
FAU - Crone, Eveline A
AU  - Crone EA
AD  - Erasmus School of Social and Behavioural Sciences, Erasmus University Rotterdam, 
      The Netherlands; Brain and Development Research Center, Leiden University, The 
      Netherlands.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20201111
PL  - Netherlands
TA  - Dev Cogn Neurosci
JT  - Developmental cognitive neuroscience
JID - 101541838
SB  - IM
EIN - Dev Cogn Neurosci. 2020 Dec 21;:100890. PMID: 33358137
MH  - Adolescent
MH  - Brain/*growth & development
MH  - Cerebral Cortex/*growth & development
MH  - Female
MH  - Humans
MH  - *Individuality
MH  - Longitudinal Studies
MH  - Male
MH  - Nucleus Accumbens/*growth & development
MH  - Prefrontal Cortex/*growth & development
PMC - PMC7677671
OTO - NOTNLM
OT  - Adolescent identity formation
OT  - Lateral PFC/ACC
OT  - Longitudinal
OT  - Medial PFC
OT  - Nucleus accumbens
OT  - Structural brain development
EDAT- 2020/11/18 06:00
MHDA- 2021/02/23 06:00
PMCR- 2020/11/11
CRDT- 2020/11/17 20:08
PHST- 2020/05/01 00:00 [received]
PHST- 2020/11/05 00:00 [revised]
PHST- 2020/11/06 00:00 [accepted]
PHST- 2020/11/18 06:00 [pubmed]
PHST- 2021/02/23 06:00 [medline]
PHST- 2020/11/17 20:08 [entrez]
PHST- 2020/11/11 00:00 [pmc-release]
AID - S1878-9293(20)30130-4 [pii]
AID - 100880 [pii]
AID - 10.1016/j.dcn.2020.100880 [doi]
PST - ppublish
SO  - Dev Cogn Neurosci. 2020 Dec;46:100880. doi: 10.1016/j.dcn.2020.100880. Epub 2020 
      Nov 11.