PMID- 33204791
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220418
IS  - 2352-5517 (Print)
IS  - 2352-5517 (Electronic)
IS  - 2352-5517 (Linking)
VI  - 22
DP  - 2020 Nov
TI  - A comparison of Sysmex-XN 2000 and Yumizen H2500 automated hematology analyzers.
PG  - e00186
LID - 10.1016/j.plabm.2020.e00186 [doi]
LID - e00186
AB  - A complete blood count is a highly automated laboratory test. The use of highly 
      advanced measurement methods increases the accuracy and sensitivity of the 
      determination of individual hematological parameters, especially in the case of 
      white blood cells differentiation. Therefore, it is necessary to make comparative 
      analyses, which involve performance of the analyzers used in daily work. The aim 
      of the study was to indicate whether the results obtained using two compared 
      analyzers show significant differences. MATERIALS AND METHODS: In this study a 
      comparative analysis of 241 peripheral blood samples from adult patients was 
      performed. The complete blood count results were obtained using two automated 
      hematology analyzers: Sysmex XN-2000 and Horiba Yumizen H2500. The Passing-Bablok 
      regression method and Bland- Altman analysis were also used to evaluate the 
      results received for both analyzers. RESULTS: Statistically significant 
      differences were found for four hematological parameters: eosinophil count, 
      immature granulocytes, mean corpuscular hemoglobin concentration (MCHC) and 
      platelet distribution width (PDW). The P value for MCHC was 0.01. Sysmex XN-2000 
      and Horiba Yumizen H2500 also showed disagreement in plate platelet distribution 
      width (PDW) (P ​= ​0.04). For other parameters both analyzers showed good 
      agreement. CONCLUSION: Based on the results of the study, it was shown that there 
      are significant differences in the measurements of hematological parameters 
      between compared analyzers.
CI  - (c) 2020 The Authors.
FAU - Malecka, Milena
AU  - Malecka M
AD  - Department of Laboratory Medicine, Medical University of Warsaw, Poland.
AD  - Central Laboratory of Central Clinical Hospital, University Clinical Center, 
      Warsaw, Poland.
FAU - Ciepiela, Olga
AU  - Ciepiela O
AD  - Department of Laboratory Medicine, Medical University of Warsaw, Poland.
AD  - Central Laboratory of Central Clinical Hospital, University Clinical Center, 
      Warsaw, Poland.
LA  - eng
PT  - Journal Article
DEP - 20201029
PL  - Netherlands
TA  - Pract Lab Med
JT  - Practical laboratory medicine
JID - 101690848
PMC - PMC7649520
OTO - NOTNLM
OT  - Automated hematology analyzer
OT  - Comparison
OT  - Complete blood count
OT  - Horiba Yumizen H2500
OT  - Sysmex XN-2000
COIS- None.
EDAT- 2020/11/19 06:00
MHDA- 2020/11/19 06:01
PMCR- 2020/10/29
CRDT- 2020/11/18 06:00
PHST- 2020/04/05 00:00 [received]
PHST- 2020/10/15 00:00 [accepted]
PHST- 2020/11/18 06:00 [entrez]
PHST- 2020/11/19 06:00 [pubmed]
PHST- 2020/11/19 06:01 [medline]
PHST- 2020/10/29 00:00 [pmc-release]
AID - S2352-5517(20)30149-9 [pii]
AID - e00186 [pii]
AID - 10.1016/j.plabm.2020.e00186 [doi]
PST - epublish
SO  - Pract Lab Med. 2020 Oct 29;22:e00186. doi: 10.1016/j.plabm.2020.e00186. 
      eCollection 2020 Nov.