PMID- 33216644 OWN - NLM STAT- MEDLINE DCOM- 20230321 LR - 20230321 IS - 1744-4160 (Electronic) IS - 1381-3455 (Linking) VI - 129 IP - 2 DP - 2023 Apr TI - Effects of green tea supplementation on serum concentrations of adiponectin in patients with type 2 diabetes mellitus: a systematic review and meta-analysis. PG - 536-543 LID - 10.1080/13813455.2020.1846202 [doi] AB - CONTEXT: A decrease in adiponectin concentration is associated with obesity-related diseases such as insulin resistance, type 2 diabetes mellitus (T2DM), and cardiovascular disease (CVD). OBJECTIVE: We aimed to evaluate the effects of green tea supplementation on serum concentrations of adiponectin in patients with T2DM. METHODS: A systematic search was performed on the ISI Web of Science, PubMed, Embase and Scopus to find articles related to the effects of the green tea supplementation on adiponectin concentrations in T2DM patients, up to June 2019. Meta-analyses were performed using both the random and fixed effects model where appropriate. RESULTS: The initial search yielded 1010 publications. Data were pooled from five trials including 333 patients with T2DM. A meta-analysis of five RCTs demonstrated that green tea supplementation significantly increased adiponectin concentrations compared to control groups. CONCLUSION: Our meta-analysis revealed that green tea supplementation increased adiponectin concentrations in patients with T2DM. FAU - Asbaghi, Omid AU - Asbaghi O AD - Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran. FAU - Fouladvand, Faezeh AU - Fouladvand F AD - Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran. FAU - Ashtary-Larky, Damoon AU - Ashtary-Larky D AD - Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. FAU - Bagheri, Reza AU - Bagheri R AD - Department of Exercise Physiology, University of Isfahan, Isfahan, Iran. FAU - Choghakhori, Razieh AU - Choghakhori R AD - Razi Herbal Medicines Research Center, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. FAU - Wong, Alexei AU - Wong A AD - Department of Health and Human Performance, Marymount University, Arlington, USA. FAU - Baker, Julien S AU - Baker JS AD - Centre for Health and Exercise Science Research, Department of Sport, Physical Education and Health, Hong Kong Baptist University, Kowloon Tong, Hong Kong. FAU - Abbasnezhad, Amir AU - Abbasnezhad A AD - Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. LA - eng PT - Journal Article PT - Meta-Analysis PT - Systematic Review DEP - 20201120 PL - England TA - Arch Physiol Biochem JT - Archives of physiology and biochemistry JID - 9510153 RN - 0 (Adiponectin) RN - 0 (Tea) SB - IM MH - Humans MH - *Diabetes Mellitus, Type 2 MH - Adiponectin MH - Tea MH - *Insulin Resistance MH - Dietary Supplements OTO - NOTNLM OT - Type 2 diabetes mellitus OT - adipokines OT - adiponectin OT - green tea OT - meta-analysis EDAT- 2020/11/21 06:00 MHDA- 2023/03/22 06:00 CRDT- 2020/11/20 17:13 PHST- 2020/11/21 06:00 [pubmed] PHST- 2023/03/22 06:00 [medline] PHST- 2020/11/20 17:13 [entrez] AID - 10.1080/13813455.2020.1846202 [doi] PST - ppublish SO - Arch Physiol Biochem. 2023 Apr;129(2):536-543. doi: 10.1080/13813455.2020.1846202. Epub 2020 Nov 20.