PMID- 33221779
OWN - NLM
STAT- MEDLINE
DCOM- 20201130
LR  - 20220418
IS  - 1119-3077 (Print)
VI  - 23
IP  - 11
DP  - 2020 Nov
TI  - Serum asymmetric-dimethylarginine, apelin and NT-pro BNP levels in dialysis 
      patients.
PG  - 1542-1547
LID - 10.4103/njcp.njcp_171_19 [doi]
AB  - BACKGROUND: The relationships among serum Apelin, Asymmetric- dimethylarginine 
      (ADMA), N-terminal probrain natriureticpeptide (NT-proBNP) levels, and blood 
      pressures in dialysis patients are not well known. MATERIALS AND METHODS: Age and 
      sex matched 30 hemodialysis (HD), 30 peritoneal dialysis (PD) patients, and 20 
      healthy controls were recruited. Serum apelin-36, ADMA, NT-proBNP levels, and 
      blood pressures of both patients and healthy controls were measured and compared. 
      RESULTS: Serum ADMA and Apelin levels in HD patients were significantly higher 
      than in PD patients. In multiple regression analyses the predictors of higher 
      serum apelin levels were higher BMI, higher ADMA and lower systolic blood 
      pressure. The predictors of serum ADMA levels were being on HD. The predictors of 
      serum NT-proBNP levels were lower serum albumin and higher systolic blood 
      pressure. CONCLUSION: Being on HD is a predictor of high ADMA levels. HD might be 
      less effective on ADMA removal than PD. It seems that higher serum apelin levels 
      related with lower sytolic blood pressure levels, whereas higher NT-proBNP levels 
      related with higher sytolic blood pressure levels indicating potential roles as 
      independent prognostic factors for systolic hypertension in dialysis patients.
FAU - Bentli, R
AU  - Bentli R
AD  - Department of Internal Medicine, Inonu University, Medical Faculty, Malatya, 
      Turkey.
FAU - Taskapan, H
AU  - Taskapan H
AD  - Department of Internal Medicine, Inonu University, Medical Faculty, Malatya, 
      Turkey.
FAU - Taskapan, M C
AU  - Taskapan MC
AD  - Department of Biochemistry, Inonu University, Medical Faculty, Malatya, Turkey.
FAU - Dogan, A
AU  - Dogan A
AD  - Department of Internal Medicine, Yuzuncu Yil University, Van, Turkey.
LA  - eng
PT  - Journal Article
PL  - India
TA  - Niger J Clin Pract
JT  - Nigerian journal of clinical practice
JID - 101150032
RN  - 0 (Apelin)
RN  - 0 (Biomarkers)
RN  - 0 (Peptide Fragments)
RN  - 0 (pro-brain natriuretic peptide (1-76))
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
RN  - 63CV1GEK3Y (N,N-dimethylarginine)
RN  - 94ZLA3W45F (Arginine)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Apelin/*blood
MH  - Arginine/*analogs & derivatives/blood
MH  - Biomarkers/blood
MH  - Blood Pressure/*physiology
MH  - Blood Pressure Determination
MH  - Female
MH  - Humans
MH  - Kidney Failure, Chronic/*blood/epidemiology/therapy
MH  - Male
MH  - Middle Aged
MH  - Natriuretic Peptide, Brain/*blood
MH  - Peptide Fragments/*blood
MH  - Peritoneal Dialysis
MH  - Renal Dialysis
OTO - NOTNLM
OT  - Apelin
OT  - NT-proBNP
OT  - asymmetric dimethylarginine
OT  - blood pressure
OT  - dialysis
COIS- None
EDAT- 2020/11/23 06:00
MHDA- 2020/12/01 06:00
CRDT- 2020/11/22 20:42
PHST- 2020/11/22 20:42 [entrez]
PHST- 2020/11/23 06:00 [pubmed]
PHST- 2020/12/01 06:00 [medline]
AID - NigerJClinPract_2020_23_11_1542_301144 [pii]
AID - 10.4103/njcp.njcp_171_19 [doi]
PST - ppublish
SO  - Niger J Clin Pract. 2020 Nov;23(11):1542-1547. doi: 10.4103/njcp.njcp_171_19.