PMID- 33222939
OWN - NLM
STAT- MEDLINE
DCOM- 20210201
LR  - 20210201
IS  - 1532-2653 (Electronic)
IS  - 0967-5868 (Linking)
VI  - 81
DP  - 2020 Nov
TI  - Prediction of outcome following laminoplasty of cervical spondylotic myelopathy: 
      Focus on the minimum clinically important difference.
PG  - 321-327
LID - S0967-5868(20)31544-7 [pii]
LID - 10.1016/j.jocn.2020.09.065 [doi]
AB  - The minimum clinically important difference (MCID) of the Japanese Orthopaedic 
      Association (JOA) score has been reported to be around 2.5 points in cervical 
      myelopathy. This study sought to define significant predictive factors on 
      achieving the MCID following laminoplasty in a large series of patients with 
      cervical spondylotic myelopathy (CSM). A total of 485 consecutive patients with 
      CSM (295 males and 190 females; mean age: 67.0 years; age range: 42-91 years) who 
      underwent laminoplasty were prospectively enrolled. The average postoperative 
      follow-up period was 26.6 months (range: 12-66 months). We calculated the 
      achieved JOA score. The relationships between outcomes and various clinical and 
      imaging predictors including comorbidity and quantitative performance tests were 
      examined. Logistic regression analysis was conducted to identify the predictors 
      correlated with a JOA score of 2.5 points or more. Clinically meaningful gains 
      were exhibited in 299 patients (61.6%) with a JOA score of >/=2.5 points, whereas 
      186 patients (38.4%) achieved a JOA score of <2.5 points. Univariate logistic 
      regression analysis showed the predictive factors with a shorter duration of CSM 
      symptoms, lower preoperative JOA scores, absence of hypertension, no use of 
      anticoagulant/antiplatelet agents, and nonsmoking status. Multivariate logistic 
      regression analysis determined that the duration of CSM symptoms (odds ratio: 
      0.771, 95% confidence interval: 0.705-0.844; p < 0.01) was the only significant 
      predictive factor for achieving JOA scores of >/=2.5 points. An important predictor 
      of MCID achievement following laminoplasty was shorter duration of CSM symptoms.
CI  - Copyright (c) 2020 Elsevier Ltd. All rights reserved.
FAU - Machino, Masaaki
AU  - Machino M
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Ando, Kei
AU  - Ando K
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Kobayashi, Kazuyoshi
AU  - Kobayashi K
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Nakashima, Hiroaki
AU  - Nakashima H
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Kanbara, Shunsuke
AU  - Kanbara S
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Ito, Sadayuki
AU  - Ito S
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Inoue, Taro
AU  - Inoue T
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Koshimizu, Hiroyuki
AU  - Koshimizu H
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
FAU - Ito, Keigo
AU  - Ito K
AD  - Department of Orthopedic Surgery, Chubu Rosai Hospital, Japan Organization of 
      Occupational Health and Safety, Nagoya, Japan. Electronic address: 
      andokei@med.nagoya-u.ac.jp.
FAU - Kato, Fumihiko
AU  - Kato F
AD  - Department of Orthopedic Surgery, Chubu Rosai Hospital, Japan Organization of 
      Occupational Health and Safety, Nagoya, Japan.
FAU - Imagama, Shiro
AU  - Imagama S
AD  - Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 
      Nagoya, Japan.
LA  - eng
PT  - Journal Article
DEP - 20201021
PL  - Scotland
TA  - J Clin Neurosci
JT  - Journal of clinical neuroscience : official journal of the Neurosurgical Society 
      of Australasia
JID - 9433352
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cervical Vertebrae/surgery
MH  - Female
MH  - Humans
MH  - Laminoplasty/*statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - *Predictive Value of Tests
MH  - Prospective Studies
MH  - Recovery of Function
MH  - Risk Factors
MH  - Spinal Cord Diseases/*surgery
MH  - Spondylosis/*surgery
MH  - Time Factors
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Cervical spondylotic myelopathy
OT  - Laminoplasty
OT  - Minimum clinically important difference
OT  - Multivariate analysis
OT  - Outcome
OT  - Prediction
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2020/11/24 06:00
MHDA- 2021/02/02 06:00
CRDT- 2020/11/23 05:27
PHST- 2020/07/09 00:00 [received]
PHST- 2020/09/13 00:00 [revised]
PHST- 2020/09/28 00:00 [accepted]
PHST- 2020/11/23 05:27 [entrez]
PHST- 2020/11/24 06:00 [pubmed]
PHST- 2021/02/02 06:00 [medline]
AID - S0967-5868(20)31544-7 [pii]
AID - 10.1016/j.jocn.2020.09.065 [doi]
PST - ppublish
SO  - J Clin Neurosci. 2020 Nov;81:321-327. doi: 10.1016/j.jocn.2020.09.065. Epub 2020 
      Oct 21.