PMID- 33229644
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20210514
IS  - 1998-3689 (Electronic)
IS  - 0301-4738 (Print)
IS  - 0301-4738 (Linking)
VI  - 68
IP  - 12
DP  - 2020 Dec
TI  - Outcome comparison between wavefront-guided and wavefront-optimized 
      photorefractive keratectomy: A systematic review and meta-analysis.
PG  - 2691-2698
LID - 10.4103/ijo.IJO_2921_20 [doi]
AB  - Photorefractive keratectomy (PRK) eye surgery is widely used for patients at risk 
      for corneal ectasia to maintain an aspheric corneal shape. Wavefront-guided (WFG) 
      ablation profile was designed to reduce pre-existing higher-order aberrations 
      (HOA). We aimed to compare the corneal aberrations and visual outcomes between 
      WFG and Wavefront Optimized (WFO) PRK in patients with myopia. Eight randomized 
      clinical trials were included. We searched PubMed, Scopus, Web of Science and 
      CENTRAL at March 2020, and updated the search in September 2020 using relevant 
      keywords, The data were extracted and pooled as Mean Difference (MD) with a 95% 
      Confidence Interval (CI), using Review Manager software (version 5.4). Pooled 
      results showed no significance between Uncorrected Distance Visual Acuity (UDVA) 
      and Corrected Distance Visual Acuity (CDVA) between both groups underwent WFG and 
      WFO PPR after three months follow up (MD = -0.03; 95% CI: [-0.06, 0.00]; P = 
      0.07), (MD = -0.02; 95% CI: [-0.04, 0.01]; P = 0.22) respectively. Although, no 
      significant difference between mean manifest cylinder after three and 12 months 
      follow up, but the total MD for mean manifest cylinder difference was 
      significantly lower with the WFG treatment method (MD = -0.12, (95% CI: 
      [0.23:-0.01], P = 0.03). This shows a slight advantage of the WFG over the WFO 
      method. The visual performance showed similarity and excellent refractive 
      outcomes in both WFO and WFG PRK. No significant statistical differences between 
      the two approaches. On further comparison, there was a slight advantage of the 
      WFG over the WFO method.
FAU - Hamam, Khaled M
AU  - Hamam KM
AD  - Faculty of Medicine, October 6 University, Giza, Egypt; International Medical 
      Research Association (IMedRA), Egypt.
FAU - Gbreel, Mohamed I
AU  - Gbreel MI
AD  - Faculty of Medicine, October 6 University, Giza, Egypt; International Medical 
      Research Association (IMedRA), Egypt.
FAU - Elsheikh, Randa
AU  - Elsheikh R
AD  - Faculty of Medicine, October 6 University, Giza, Egypt; International Medical 
      Research Association (IMedRA), Egypt.
FAU - Benmelouka, Amira Y
AU  - Benmelouka AY
AD  - International Medical Research Association (IMedRA), Egypt; Faculty of Medicine, 
      University of Algiers, Algiers, Algeria.
FAU - Ouerdane, Yassamine
AU  - Ouerdane Y
AD  - International Medical Research Association (IMedRA), Egypt; Faculty of Medicine, 
      Saad Dahlab University, Blida, Algeria.
FAU - Hassan, Amr K
AU  - Hassan AK
AD  - International Medical Research Association (IMedRA); Faculty of Medicine, 
      South-Valley University, Qena, Egypt.
FAU - Hamdallah, Aboalmagd
AU  - Hamdallah A
AD  - International Medical Research Association (IMedRA); Faculty of Medicine Al-Azhar 
      University, Damietta, Egypt.
FAU - Elsnhory, Ahmed B
AU  - Elsnhory AB
AD  - International Medical Research Association (IMedRA); Faculty of Medicine, 
      Al-Azhar University, Cairo, Egypt.
FAU - Nourelden, Anas Z
AU  - Nourelden AZ
AD  - International Medical Research Association (IMedRA); Faculty of Medicine, 
      Al-Azhar University, Cairo, Egypt.
FAU - Masoud, Ahmed T
AU  - Masoud AT
AD  - International Medical Research Association (IMedRA); Faculty of Medicine, Fayoum 
      University, Fayoum, Egypt.
FAU - Ali, Asmaa A
AU  - Ali AA
AD  - International Medical Research Association (IMedRA); Faculty of Medicine, Assiut 
      University, Assiut, Egypt.
FAU - Ragab, Khaled M
AU  - Ragab KM
AD  - International Medical Research Association (IMedRA); Faculty of Medicine, 
      El-Minia University, Minia, Egypt.
FAU - Ibrahim, Ahmed M
AU  - Ibrahim AM
AD  - International Medical Research Association (IMedRA); Faculty of Medicine, 
      Al-Azhar University, Cairo, Egypt.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
PL  - India
TA  - Indian J Ophthalmol
JT  - Indian journal of ophthalmology
JID - 0405376
SB  - IM
MH  - *Corneal Wavefront Aberration/diagnosis
MH  - Humans
MH  - Lasers, Excimer/therapeutic use
MH  - *Photorefractive Keratectomy
MH  - Prospective Studies
MH  - Refraction, Ocular
MH  - Treatment Outcome
PMC - PMC7856933
OTO - NOTNLM
OT  - Higher-order aberration
OT  - meta-analysis
OT  - myopia
OT  - wavefront-guided photorefractive keratectomy
OT  - wavefront-optimized photorefractive keratectomy
COIS- None
EDAT- 2020/11/25 06:00
MHDA- 2021/05/15 06:00
PMCR- 2020/12/01
CRDT- 2020/11/24 05:57
PHST- 2020/11/24 05:57 [entrez]
PHST- 2020/11/25 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
PHST- 2020/12/01 00:00 [pmc-release]
AID - IndianJOphthalmol_2020_68_12_2691_301266 [pii]
AID - IJO-68-2691 [pii]
AID - 10.4103/ijo.IJO_2921_20 [doi]
PST - ppublish
SO  - Indian J Ophthalmol. 2020 Dec;68(12):2691-2698. doi: 10.4103/ijo.IJO_2921_20.