PMID- 33229793 OWN - NLM STAT- MEDLINE DCOM- 20210728 LR - 20220531 IS - 1347-7439 (Electronic) IS - 0916-7250 (Print) IS - 0916-7250 (Linking) VI - 83 IP - 1 DP - 2021 Jan 14 TI - Disseminated histiocytic sarcoma in Asian palm civet (Paradoxurus hermaphroditus). PG - 108-111 LID - 10.1292/jvms.20-0403 [doi] AB - This case study had focused on a male, 7-year-old Asian palm civet (Paradoxurus hermaphroditus) with a history of biting its tail and the development of skin masses around its inguinal area, prior to its death. Macroscopically, multiple firm white nodular masses of 0.5-5 cm in diameter were found in the subcutis of the inguinal area, and in the lungs, spleen and liver. Microscopically, masses in the skin, lungs and spleen were composed of neoplastic spindle cells admixed with mononuclear cells and multinucleated giant cells. The neoplastic cells were arranged in a sheet pattern. Immunohistochemically, the neoplastic cells were immunohistochemically positive for vimentin, Iba-1, CD 204 and Human leukocyte antigen (HLA)-DR, while the cells were negative for cytokeratin and smooth muscle actin. Based on the histopathological and immunohistochemical results, disseminated histiocytic sarcoma was diagnosed. FAU - Boonsri, Kittikorn AU - Boonsri K AD - Veterinary Diagnostic Center, Chiang Mai University Animal Hospital, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand. FAU - Dechkajorn, Sakorn AU - Dechkajorn S AD - Chiang Mai Night Safari, Chiang Mai 50230, Thailand. FAU - Photichai, Kornravee AU - Photichai K AD - Veterinary Diagnostic Center, Chiang Mai University Animal Hospital, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand. FAU - Srivorakul, Saralee AU - Srivorakul S AD - Veterinary Diagnostic Center, Chiang Mai University Animal Hospital, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand. FAU - Boonsriroj, Hassadin AU - Boonsriroj H AD - Department of Pathology, Faculty of Veterinary Medicine, Mahanakon University of Technology, Bangkok 10530, Thailand. FAU - Thongtharb, Atigan AU - Thongtharb A AD - Department of Companion Animal and Wildlife Clinic, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand. AD - Small Animal Hospital, Chiang Mai University Animal Hospital, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. FAU - Pringproa, Kidsadagon AU - Pringproa K AD - Veterinary Diagnostic Center, Chiang Mai University Animal Hospital, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand. AD - Department of Veterinary Biosciences and Veterinary Public Health, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand. LA - eng PT - Case Reports PT - Journal Article DEP - 20201124 PL - Japan TA - J Vet Med Sci JT - The Journal of veterinary medical science JID - 9105360 SB - IM MH - Animals MH - Giant Cells MH - *Histiocytic Sarcoma/veterinary MH - Male MH - Viverridae PMC - PMC7870405 OTO - NOTNLM OT - civet OT - disseminated histiocytic sarcoma COIS- The author(s) declared no conflicts of interest with respect to the authorship and/or publication of this article. EDAT- 2020/11/25 06:00 MHDA- 2021/07/29 06:00 PMCR- 2021/01/01 CRDT- 2020/11/24 05:57 PHST- 2020/11/25 06:00 [pubmed] PHST- 2021/07/29 06:00 [medline] PHST- 2020/11/24 05:57 [entrez] PHST- 2021/01/01 00:00 [pmc-release] AID - 20-0403 [pii] AID - 10.1292/jvms.20-0403 [doi] PST - ppublish SO - J Vet Med Sci. 2021 Jan 14;83(1):108-111. doi: 10.1292/jvms.20-0403. Epub 2020 Nov 24.