PMID- 33230808
OWN - NLM
STAT- MEDLINE
DCOM- 20210617
LR  - 20210617
IS  - 1879-3479 (Electronic)
IS  - 0020-7292 (Linking)
VI  - 153
IP  - 3
DP  - 2021 Jun
TI  - Clinical characteristics of primary Fallopian tube carcinoma: A 
      single-institution retrospective study of 57 cases.
PG  - 405-411
LID - 10.1002/ijgo.13497 [doi]
AB  - OBJECTIVE: To analyze the clinical profile and prognosis of primary Fallopian 
      tube cancer (PFTC) in order to improve earlier diagnosis. METHODS: In this 
      retrospective study, 57 women with PFTC were assessed from 2006 to 2016. 
      Pathology, clinical index, recurrence, and survival were analyzed. RESULTS: Mean 
      age was 57.35 +/- 9.01 years, and 73% (19/26) of the patients with early-stage PFTC 
      (I/II) were aged less than 60 years. Of patients who presented with abnormal 
      vaginal bleeding, 75% (9/12) were at an early stage and their condition was often 
      misdiagnosed as endometrial carcinoma preoperatively. In patients with Stages 
      I/II and Stages III/IV PFTC, 59.09% (13/22) and 96.43% (27/28), respectively, had 
      adnexal masses on color Doppler ultrasonography. The 5-year overall survival (OS) 
      and disease-free survival rates were 69.23% and 44.23%, respectively, and 
      univariate analysis showed that tumor stage and residual tumor size significantly 
      affected the two survival rates. CONCLUSION: Primary Fallopian tube cancer is 
      more likely to be misdiagnosed in patients aged less than 60 years or those 
      presenting with vaginal bleeding at the premenopausal stage. Magnetic resonance 
      imaging, cervical smear, and endometrial brush may be helpful for early PFTC 
      diagnosis. Satisfactory cytoreductive surgery is critical because tumor stage and 
      residual tumor size are significantly associated with the OS rate.
CI  - (c) 2020 International Federation of Gynecology and Obstetrics.
FAU - Ma, Zhihua
AU  - Ma Z
AD  - Department of Gynecology & Obstetrics, The First Affiliated Hospital of Xi'an 
      Jiaotong University, Xi'an, Shaanxi, China.
FAU - Gao, Li
AU  - Gao L
AD  - Department of Gynecology & Obstetrics, The First Affiliated Hospital of Xi'an 
      Jiaotong University, Xi'an, Shaanxi, China.
FAU - Li, Han
AU  - Li H
AD  - Department of Gynecology & Obstetrics, The First Affiliated Hospital of Xi'an 
      Jiaotong University, Xi'an, Shaanxi, China.
FAU - Li, Jie
AU  - Li J
AD  - Department of Pathology, The First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, Shaanxi, China.
FAU - Zhang, Guanjun
AU  - Zhang G
AD  - Department of Pathology, The First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, Shaanxi, China.
FAU - Xue, Yan
AU  - Xue Y
AD  - Department of Gynecology & Obstetrics, The First Affiliated Hospital of Xi'an 
      Jiaotong University, Xi'an, Shaanxi, China.
LA  - eng
GR  - 2017JM8055/Shannxi Natural Science Basic Research Program - General Projects/
GR  - 2019YK8/Science Foundation of The First Affiliated Hospital of Xi'an Jiaotong 
      University/
PT  - Journal Article
DEP - 20201231
PL  - United States
TA  - Int J Gynaecol Obstet
JT  - International journal of gynaecology and obstetrics: the official organ of the 
      International Federation of Gynaecology and Obstetrics
JID - 0210174
RN  - 0 (CA-125 Antigen)
RN  - 0 (MUC16 protein, human)
RN  - 0 (Membrane Proteins)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - CA-125 Antigen/blood
MH  - Carcinoma/diagnostic imaging/*mortality/*pathology/therapy
MH  - Diagnostic Errors
MH  - Disease-Free Survival
MH  - Fallopian Tube Neoplasms/diagnostic imaging/*mortality/*pathology/therapy
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Membrane Proteins/blood
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Retrospective Studies
MH  - Survival Rate
MH  - Tomography, X-Ray Computed
MH  - Ultrasonography, Doppler, Color
MH  - Uterine Hemorrhage/etiology
OTO - NOTNLM
OT  - clinical characteristics
OT  - primary Fallopian tube carcinoma
OT  - prognosis
OT  - treatment
EDAT- 2020/11/25 06:00
MHDA- 2021/06/22 06:00
CRDT- 2020/11/24 06:07
PHST- 2020/10/02 00:00 [revised]
PHST- 2020/06/28 00:00 [received]
PHST- 2020/11/21 00:00 [accepted]
PHST- 2020/11/25 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
PHST- 2020/11/24 06:07 [entrez]
AID - 10.1002/ijgo.13497 [doi]
PST - ppublish
SO  - Int J Gynaecol Obstet. 2021 Jun;153(3):405-411. doi: 10.1002/ijgo.13497. Epub 
      2020 Dec 31.