PMID- 33232905
OWN - NLM
STAT- MEDLINE
DCOM- 20210827
LR  - 20210827
IS  - 1878-4291 (Electronic)
IS  - 0968-4328 (Linking)
VI  - 141
DP  - 2021 Feb
TI  - Biosynthesis of zinc oxide nanoparticles using leaf extracts of Alchornea 
      laxiflora and its tyrosinase inhibition and catalytic studies.
PG  - 102964
LID - S0968-4328(20)30213-4 [pii]
LID - 10.1016/j.micron.2020.102964 [doi]
AB  - Zinc oxide nanoparticles (ZnO-NPs) were synthesized using a simple, low cost and 
      safe method involving aqueous leaf extracts of Alchornea laxiflora and a zinc 
      precursor salt. The nanoparticles were characterized by ultraviolet-visible 
      (UV-vis), Fourier transform (FT-IR) spectroscopy, Energy dispersive X-ray (EDX), 
      X-ray diffraction (XRD) and Scanning electron microscope (SEM). They were 
      evaluated for their potentials as tyrosinase inhibitors and as catalysts in the 
      degradation of Congo red dye. The UV-vis spectra gave characteristic surface 
      Plasmon bands within the range 276-456 nm. The band gap energies of the ZnO-NPs 
      were of the range, 2.50-3.67 ev. The SEM results showed average sizes of 29 nm 
      and 38 nm for particles obtained using 1 mL and 2 mL of the plant extracts 
      respectively. EDX plot showed the elemental compositions of the nanoparticles 
      with zinc and oxygen being pronounced. The ZnO nanoparticles exhibited good 
      photocatalytic efficiency of 87 % degradation of Congo red (CR) dye molecules in 
      60 min, They also showed good anti-tyrosinase ability with an IC50 of 66.28 
      mug/mL. Overall the biogenic ZnO nanoparticles are promising materials for dual 
      applications as photocatalysts in the degradation of Congo red dye and as 
      tyrosinase inhibitors.
CI  - Copyright (c) 2020 Elsevier Ltd. All rights reserved.
FAU - Ekennia, Anthony
AU  - Ekennia A
AD  - Department of Chemistry/Biochemistry and Molecular Biology, Alex Ekwueme Federal 
      University, Ndufu-Alike (AE-FUNAI), P.M.B, 1010, Abakaliki, Ebonyi State, 
      Nigeria. Electronic address: anthony.ekennia@funai.edu.ng.
FAU - Uduagwu, Dickson
AU  - Uduagwu D
AD  - Department of Chemistry/Biochemistry and Molecular Biology, Alex Ekwueme Federal 
      University, Ndufu-Alike (AE-FUNAI), P.M.B, 1010, Abakaliki, Ebonyi State, 
      Nigeria.
FAU - Olowu, Olawale
AU  - Olowu O
AD  - Department of Chemistry/Biochemistry and Molecular Biology, Alex Ekwueme Federal 
      University, Ndufu-Alike (AE-FUNAI), P.M.B, 1010, Abakaliki, Ebonyi State, 
      Nigeria.
FAU - Nwanji, Obianuju
AU  - Nwanji O
AD  - Department of Chemistry/Biochemistry and Molecular Biology, Alex Ekwueme Federal 
      University, Ndufu-Alike (AE-FUNAI), P.M.B, 1010, Abakaliki, Ebonyi State, 
      Nigeria.
FAU - Oje, Obinna
AU  - Oje O
AD  - Department of Chemistry/Biochemistry and Molecular Biology, Alex Ekwueme Federal 
      University, Ndufu-Alike (AE-FUNAI), P.M.B, 1010, Abakaliki, Ebonyi State, 
      Nigeria.
FAU - Daniel, Blessing
AU  - Daniel B
AD  - Department of Chemistry/Biochemistry and Molecular Biology, Alex Ekwueme Federal 
      University, Ndufu-Alike (AE-FUNAI), P.M.B, 1010, Abakaliki, Ebonyi State, 
      Nigeria.
FAU - Mgbii, Sandra
AU  - Mgbii S
AD  - Department of Chemistry/Biochemistry and Molecular Biology, Alex Ekwueme Federal 
      University, Ndufu-Alike (AE-FUNAI), P.M.B, 1010, Abakaliki, Ebonyi State, 
      Nigeria.
FAU - Emma-Uba, Chimerem
AU  - Emma-Uba C
AD  - Department of Chemistry/Biochemistry and Molecular Biology, Alex Ekwueme Federal 
      University, Ndufu-Alike (AE-FUNAI), P.M.B, 1010, Abakaliki, Ebonyi State, 
      Nigeria.
LA  - eng
PT  - Journal Article
DEP - 20201108
PL  - England
TA  - Micron
JT  - Micron (Oxford, England : 1993)
JID - 9312850
RN  - 0 (Plant Extracts)
RN  - EC 1.14.18.1 (Monophenol Monooxygenase)
RN  - SOI2LOH54Z (Zinc Oxide)
SB  - IM
MH  - Biocatalysis
MH  - Metal Nanoparticles/chemistry
MH  - Microscopy, Electron, Scanning
MH  - Monophenol Monooxygenase/*antagonists & inhibitors
MH  - Nanoparticles/*chemistry/*metabolism
MH  - Plant Extracts/*chemistry
MH  - Plant Leaves/*chemistry
MH  - Spectrometry, X-Ray Emission
MH  - Zinc Oxide/*metabolism
OTO - NOTNLM
OT  - Alchornea laxiflora
OT  - Nanoparticles
OT  - Tyrosinase inhibition: photocatalysis
OT  - Zinc oxide
EDAT- 2020/11/25 06:00
MHDA- 2021/08/28 06:00
CRDT- 2020/11/24 20:11
PHST- 2020/07/06 00:00 [received]
PHST- 2020/10/11 00:00 [revised]
PHST- 2020/10/13 00:00 [accepted]
PHST- 2020/11/25 06:00 [pubmed]
PHST- 2021/08/28 06:00 [medline]
PHST- 2020/11/24 20:11 [entrez]
AID - S0968-4328(20)30213-4 [pii]
AID - 10.1016/j.micron.2020.102964 [doi]
PST - ppublish
SO  - Micron. 2021 Feb;141:102964. doi: 10.1016/j.micron.2020.102964. Epub 2020 Nov 8.