PMID- 33233613
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240330
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 9
IP  - 11
DP  - 2020 Nov 20
TI  - Remote Monitoring of Cardiac Implantable Electronic Devices in Patients 
      Undergoing Hybrid Comprehensive Telerehabilitation in Comparison to the Usual 
      Care. Subanalysis from Telerehabilitation in Heart Failure Patients (TELEREH-HF) 
      Randomised Clinical Trial.
LID - 10.3390/jcm9113729 [doi]
LID - 3729
AB  - BACKGROUND: The impact of cardiac rehabilitation on the number of alerts in 
      patients with remote monitoring (RM) of cardiac implantable electronic devices 
      (CIEDs) is unknown. We compared alerts in RM and outcomes in patients with CIEDs 
      undergoing hybrid comprehensive telerehabilitation (HCTR) versus usual care (UC). 
      METHODS: Patients with heart failure (HF) after a hospitalization due to 
      worsening HF within the last 6 months (New York Heart Association (NYHA) class 
      I-III and left ventricular ejection fraction (LVEF) </=40%) were enrolled in the 
      TELEREH-HF study and randomised 1:1 to HCTR or UC. Patients with HCTR and CIEDs 
      received RM (HCTR-RM). Patients with UC and CIEDs were offered RM optionally 
      (UC-RM). Data from the initial 9 weeks of the study were analysed. RESULTS: Of 
      850 enrolled patients, 208 were in the HCTR-RM group and 62 in the UC-RM group. 
      The HCTR-RM group was less likely to have alerts of intrathoracic impedance (TI) 
      decrease (p < 0.001), atrial fibrillation (AF) occurrence (p = 0.031) and lower 
      mean number of alerts per patient associated with TI decrease (p < 0.0001) and AF 
      (p = 0.019) than the UC-RM group. HCTR significantly decreased the occurrence of 
      alerts in RM of CIEDs, 0.360 (95%CI, 0.189-0.686; p = 0.002), in multivariable 
      regression analysis. There were two deaths in the HCTR-RM group (0.96%) and no 
      deaths in the UC-RM group (p = 1.0). There were no differences in the number of 
      hospitalised patients between the HCTR-RM and UC-RM group (p = 1.0). CONCLUSIONS: 
      HCTR significantly reduced the number of patients with RM alerts of CIEDs related 
      to TI decrease and AF occurrence. There were no differences in mortality or 
      hospitalisation rates between HCTR-RM and UC-RM groups.
FAU - Pluta, Slawomir
AU  - Pluta S
AD  - Department of Cardiology and Angiology, Silesian Centre for Heart Disease, 41-800 
      Zabrze, Poland.
FAU - Piotrowicz, Ewa
AU  - Piotrowicz E
AD  - Telecardiology Center, National Institute of Cardiology, 04-628 Warsaw, Poland.
FAU - Piotrowicz, Ryszard
AU  - Piotrowicz R
AUID- ORCID: 0000-0002-9571-1694
AD  - National Institute of Cardiology, 04-628 Warsaw, Poland.
AD  - Warsaw Academy of Medicine Rehabilitation, 02-091 Warsaw, Poland.
FAU - Lewicka, Ewa
AU  - Lewicka E
AUID- ORCID: 0000-0002-0162-2659
AD  - Department of Cardiology and Electrotherapy, Medical University of Gdansk, 80-211 
      Gdansk, Poland.
FAU - Zareba, Wojciech
AU  - Zareba W
AD  - Department of Medicine, University of Rochester Medical Center, Rochester, NY 
      14642, USA.
FAU - Koziel, Monika
AU  - Koziel M
AUID- ORCID: 0000-0003-0384-1975
AD  - Department of Cardiology and Angiology, Silesian Centre for Heart Disease, 41-800 
      Zabrze, Poland.
FAU - Kowalik, Ilona
AU  - Kowalik I
AD  - National Institute of Cardiology, 04-628 Warsaw, Poland.
FAU - Pencina, Michael J
AU  - Pencina MJ
AD  - Department of Biostatistics and Bioinformatics, Duke University School of 
      Medicine, Durham, NC 27707, USA.
FAU - Oreziak, Artur
AU  - Oreziak A
AD  - Department of Arrhythmia, National Institute of Cardiology, 04-628 Warsaw, 
      Poland.
FAU - Cacko, Andrzej
AU  - Cacko A
AD  - Department of Medical Informatics and Telemedicine, Medical University of Warsaw, 
      02-091 Warsaw, Poland.
FAU - Szalewska, Dominika
AU  - Szalewska D
AD  - Rehabilitation Medicine, Medical University of Gdansk, 80-211 Gdansk, Poland.
FAU - Glowczynska, Renata
AU  - Glowczynska R
AD  - Department of Cardiology, Medical University of Warsaw, 02-091Warsaw, Poland.
FAU - Banach, Maciej
AU  - Banach M
AUID- ORCID: 0000-0001-6690-6874
AD  - Department of Hypertension, Medical University of Lodz, 92-213 Lodz, Poland.
FAU - Opolski, Grzegorz
AU  - Opolski G
AD  - Department of Cardiology, Medical University of Warsaw, 02-091Warsaw, Poland.
FAU - Orzechowski, Piotr
AU  - Orzechowski P
AD  - Telecardiology Center, National Institute of Cardiology, 04-628 Warsaw, Poland.
FAU - Irzmanski, Robert
AU  - Irzmanski R
AD  - Department of Internal Medicine and Cardiac Rehabilitation, Medical University of 
      Lodz, 92-213 Lodz, Poland.
FAU - Kalarus, Zbigniew
AU  - Kalarus Z
AD  - Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Division 
      of Medical Sciences in Zabrze, Medical University of Silesia, 41-800 Zabrze, 
      Poland.
LA  - eng
GR  - Grant number STRATEGMED1/233547/13/NCBR/2015/National Centre for Research and 
      Development, Warsaw, Poland/
PT  - Journal Article
DEP - 20201120
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC7699808
OTO - NOTNLM
OT  - cardiac implantable electronic devices
OT  - heart failure
OT  - hybrid comprehensive telerehabilitation
OT  - remote monitoring
COIS- The authors were supported by National Centre for Research and Development, 
      Warsaw, Poland.
EDAT- 2020/11/26 06:00
MHDA- 2020/11/26 06:01
PMCR- 2020/11/20
CRDT- 2020/11/25 01:04
PHST- 2020/10/13 00:00 [received]
PHST- 2020/11/13 00:00 [revised]
PHST- 2020/11/17 00:00 [accepted]
PHST- 2020/11/25 01:04 [entrez]
PHST- 2020/11/26 06:00 [pubmed]
PHST- 2020/11/26 06:01 [medline]
PHST- 2020/11/20 00:00 [pmc-release]
AID - jcm9113729 [pii]
AID - jcm-09-03729 [pii]
AID - 10.3390/jcm9113729 [doi]
PST - epublish
SO  - J Clin Med. 2020 Nov 20;9(11):3729. doi: 10.3390/jcm9113729.