PMID- 33234195
OWN - NLM
STAT- MEDLINE
DCOM- 20210531
LR  - 20210531
IS  - 1522-6662 (Electronic)
IS  - 1098-3511 (Linking)
VI  - 23
IP  - 6
DP  - 2020 Nov 5
TI  - Assessment of Bipolar Radiofrequency Ablation Combined with Coronary Artery 
      Bypass Surgery for Management of Atrial Fibrillation in Cardiac Patients.
PG  - E826-E832
LID - 10.1532/hsf.3283 [doi]
AB  - BACKGROUND: Atrial fibrillation (AF) is a common problem in patients undergoing 
      coronary artery bypass graft (CABG). For AF ablation, bipolar radiofrequency 
      ablation (BRA) achieves complete transmural ablation lines and reduces the risk 
      of treatment failure. We analyzed the efficacy of BRA for sinus rhythm 
      restoration in patients with AF undergoing CABG. METHODS: This prospective study 
      included patients with permanent or paroxysmal AF scheduled to undergo BRA 
      combined with CABG in our institution from May 2014 to June 2020. After discharge 
      from hospital, all patients were seen every 6 months over 5 years to evaluate 
      survival, sinus rhythm restoration, and New York Heart Association (NYHA) class. 
      RESULTS: We enrolled 168 patients, 97 (57.7%) with permanent AF (group I) and 71 
      (42.3%) with paroxysmal AF (group II) at 60 months. We found that group II 
      patients had better sinus rhythm restoration rates after BRA with CABG than group 
      I patients (P = .005). Overall mortality at 60 months was significantly lower in 
      group II patients (2 [2.8%]) than patients in group I (14 [14.4%]; P = .01). The 
      survival rate was significantly higher in group II than in group I (94% versus 
      72%; P = .0003) as shown by Kaplan-Meier analysis. The 95% confidence interval of 
      the Cox hazards survival regression ratio was significantly different between 
      groups (0.1792 [0.04069 to 0.7896]; P = .006). Long-term AF (>3 years) before BRA 
      with CABG and permanent AF type were identified as predictors of post-BRA 
      recurrent AF (P = .0001 and P = .005, respectively). NYHA class improved 
      significantly at 60 months compared with baseline (P < .0001). CONCLUSIONS: This 
      study identified preoperative AF type and duration as predictors of the success 
      of BRA combined with CABG.
FAU - Singab, Hamdy
AU  - Singab H
AD  - Department of Cardiovascular and Thoracic Surgery, Faculty of Medicine, Ain Shams 
      University, Ain Shams University Hospitals, Abbasia Square, Cairo, Egypt. 
      hamdi_singab@hotmail.com.
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
DEP - 20201105
PL  - United States
TA  - Heart Surg Forum
JT  - The heart surgery forum
JID - 100891112
SB  - IM
MH  - Atrial Fibrillation/complications/physiopathology/*surgery
MH  - Catheter Ablation/*methods
MH  - Coronary Artery Bypass/*methods
MH  - Coronary Artery Disease/complications/*surgery
MH  - Double-Blind Method
MH  - Electrocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Rate/*physiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Treatment Outcome
EDAT- 2020/11/26 06:00
MHDA- 2021/06/01 06:00
CRDT- 2020/11/25 05:31
PHST- 2020/08/24 00:00 [received]
PHST- 2020/09/08 00:00 [accepted]
PHST- 2020/11/25 05:31 [entrez]
PHST- 2020/11/26 06:00 [pubmed]
PHST- 2021/06/01 06:00 [medline]
AID - 10.1532/hsf.3283 [doi]
PST - epublish
SO  - Heart Surg Forum. 2020 Nov 5;23(6):E826-E832. doi: 10.1532/hsf.3283.