PMID- 33236165 OWN - NLM STAT- MEDLINE DCOM- 20210308 LR - 20210730 IS - 1435-1250 (Electronic) IS - 0340-1855 (Print) IS - 0340-1855 (Linking) VI - 80 IP - 2 DP - 2021 Mar TI - [Paraneoplastic subacute cutaneous lupus erythematosus]. PG - 189-193 LID - 10.1007/s00393-020-00926-9 [doi] AB - Subacute cutaneous lupus erythematosus (SCLE) is a subtype of cutaneous lupus erythematosus characterized by high photosensitivity, the occurrence of annular or papulosquamous skin lesions located in body regions exposed to UV light, the presence of anti-Ro/SS‑A antibodies, and mild systemic involvement, such as arthralgia and myalgia. Similar to other subtypes of cutaneous lupus erythematosus, certain trigger factors exist for the development of SCLE, such as exposure to UV light, cigarette smoking and drugs. Rheumatic diseases, such as dermatomyositis, have been known as paraneoplastic syndromes for a long time. In recent years, there has been an accumulation of publications on the association of SCLE with malignant diseases. This article reports the case of a 78-year-old female patient who was diagnosed with the concomitant development of SCLE and gastric carcinoma. In all older patients with SCLE, patients with widespread skin affection outside the UV-exposed body areas or patients with B‑symptoms, the presence of a paraneoplastic SCLE should be considered and appropriate diagnostic steps should be initiated to screen for an associated neoplastic disease. FAU - Rezazadegan, R AU - Rezazadegan R AD - Klinik fur Dermatologie, Venerologie und Allergologie, HELIOS St. Elisabeth Klinik Oberhausen, Universitat Witten/Herdecke, Josefstr. 3, 46045, Oberhausen, Deutschland. FAU - Koushk-Jalali, B AU - Koushk-Jalali B AD - Klinik fur Dermatologie, Venerologie und Allergologie, HELIOS St. Elisabeth Klinik Oberhausen, Universitat Witten/Herdecke, Josefstr. 3, 46045, Oberhausen, Deutschland. FAU - Kuntz, T AU - Kuntz T AD - Klinik fur Dermatologie, Venerologie und Allergologie, HELIOS St. Elisabeth Klinik Oberhausen, Universitat Witten/Herdecke, Josefstr. 3, 46045, Oberhausen, Deutschland. FAU - Oellig, F AU - Oellig F AD - Institut fur Pathologie, Mulheim an der Ruhr, Deutschland. FAU - Tigges, C AU - Tigges C AD - Klinik fur Dermatologie, Venerologie und Allergologie, HELIOS St. Elisabeth Klinik Oberhausen, Universitat Witten/Herdecke, Josefstr. 3, 46045, Oberhausen, Deutschland. FAU - Kreuter, A AU - Kreuter A AD - Klinik fur Dermatologie, Venerologie und Allergologie, HELIOS St. Elisabeth Klinik Oberhausen, Universitat Witten/Herdecke, Josefstr. 3, 46045, Oberhausen, Deutschland. Alexander.Kreuter@helios-gesundheit.de. LA - ger PT - Case Reports PT - Journal Article TT - Paraneoplastischer subakut kutaner Lupus erythematodes. DEP - 20201124 PL - Germany TA - Z Rheumatol JT - Zeitschrift fur Rheumatologie JID - 0414162 RN - 0 (Autoantibodies) SB - IM MH - Aged MH - Autoantibodies MH - Female MH - Humans MH - *Lupus Erythematosus, Cutaneous/diagnosis MH - *Paraneoplastic Syndromes/diagnosis MH - *Rheumatic Diseases MH - Skin PMC - PMC7929939 OTO - NOTNLM OT - Cutaneous lupus erythematosus OT - Gastric cancer OT - Hydroxychloroquine OT - Paraneoplastic syndrome OT - Subacute cutaneous lupus erythematosus EDAT- 2020/11/26 06:00 MHDA- 2021/03/09 06:00 PMCR- 2020/11/24 CRDT- 2020/11/25 05:48 PHST- 2020/10/29 00:00 [accepted] PHST- 2020/11/26 06:00 [pubmed] PHST- 2021/03/09 06:00 [medline] PHST- 2020/11/25 05:48 [entrez] PHST- 2020/11/24 00:00 [pmc-release] AID - 10.1007/s00393-020-00926-9 [pii] AID - 926 [pii] AID - 10.1007/s00393-020-00926-9 [doi] PST - ppublish SO - Z Rheumatol. 2021 Mar;80(2):189-193. doi: 10.1007/s00393-020-00926-9. Epub 2020 Nov 24.