PMID- 33236674
OWN - NLM
STAT- MEDLINE
DCOM- 20210831
LR  - 20210831
IS  - 1758-1125 (Electronic)
IS  - 0268-3555 (Linking)
VI  - 36
IP  - 5
DP  - 2021 Jun
TI  - A comparative analysis of the efficacy and safety of therapeutic interventions in 
      phlegmasia cerulea dolens.
PG  - 392-400
LID - 10.1177/0268355520975581 [doi]
AB  - OBJECTIVE: Present an institution's experience in management of phlegmasia 
      cerulea dolens (PCD) with a review of the literature. METHODS: Beaumont Health's 
      electronic record database was queried between July 2009 and November 2019 for 
      inpatients with PCD. A comprehensive chart review was performed to verify the 
      accuracy of the diagnosis and extract relevant parameters. Medians and 
      proportions are reported. RESULTS: 22 patients met the criteria for PCD. 59% 
      females. Median age 65 years (interquartile range [IQR] 22). Obesity was present 
      in 45% of patients. 18 patients underwent either a single modality (55.5%) or a 
      multimodality therapeutic approach (44.5%). Limb amputation was required in a 
      third of patients who underwent catheter-directed thrombolysis or percutaneous 
      thrombectomy alone. Death was highest after percutaneous thrombectomy alone (66%) 
      followed by pharmacomechanical catheter-directed thrombolysis alone (50%). 
      CONCLUSION: Percutaneous interventions have become the mainstay in management of 
      PCD as demonstrated in this large retrospective analysis and supported by 
      literature review.
FAU - Said, Ahmad
AU  - Said A
AUID- ORCID: 0000-0003-2629-592X
AD  - Department of Internal Medicine, Department of Cardiovascular Medicine, 
      7005Beaumont Health, Troy, MI, USA.
AD  - Clinical Instructor of Medicine, 6918Oakland University William Beaumont School 
      of Medicine, Rochester, MI, USA.
FAU - Sahlieh, Ali
AU  - Sahlieh A
AD  - Department of Internal Medicine, ProMedica Toledo Hospital, Toledo, OH, USA.
FAU - Sayed, Luay
AU  - Sayed L
AD  - Department of Internal Medicine, Department of Cardiovascular Medicine, 
      7005Beaumont Health, Troy, MI, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20201125
PL  - England
TA  - Phlebology
JT  - Phlebology
JID - 9012921
SB  - IM
MH  - Female
MH  - Humans
MH  - Male
MH  - Retrospective Studies
MH  - Thrombectomy
MH  - Thrombolytic Therapy
MH  - *Thrombophlebitis/therapy
MH  - *Venous Thrombosis
OTO - NOTNLM
OT  - Phlegmasia cerulea dolens
OT  - catheter-directed therapies
OT  - critical limb ischemia
OT  - endovascular interventions
OT  - thrombectomy
EDAT- 2020/11/26 06:00
MHDA- 2021/09/01 06:00
CRDT- 2020/11/25 08:36
PHST- 2020/11/26 06:00 [pubmed]
PHST- 2021/09/01 06:00 [medline]
PHST- 2020/11/25 08:36 [entrez]
AID - 10.1177/0268355520975581 [doi]
PST - ppublish
SO  - Phlebology. 2021 Jun;36(5):392-400. doi: 10.1177/0268355520975581. Epub 2020 Nov 
      25.