PMID- 33238532
OWN - NLM
STAT- MEDLINE
DCOM- 20210128
LR  - 20210128
IS  - 1660-4601 (Electronic)
IS  - 1661-7827 (Print)
IS  - 1660-4601 (Linking)
VI  - 17
IP  - 22
DP  - 2020 Nov 23
TI  - Characteristics of Psychosocial Factors in Liver Transplantation Candidates with 
      Alcoholic Liver Disease before Transplantation: A Retrospective Study in a Single 
      Center in Taiwan.
LID - 10.3390/ijerph17228696 [doi]
LID - 8696
AB  - Liver transplantation (LT) is an essential treatment for end-stage alcoholic 
      liver disease (ALD). The patients' psychosocial condition plays a vital role in 
      post-transplantation prognosis. A survey of the candidates' psychosocial 
      wellbeing is necessary before LT. This study aims to investigate the psychosocial 
      characteristics, including the depression degree, family function, alcohol use 
      duration, and alcohol abstinence period, of LT candidates with ALD. In addition, 
      451 candidates for LT due to ALD were enrolled. They received psychosocial 
      evaluations, including depression scale (Hamilton depression rating scale) and 
      family functioning assessment (adaptability, partnership, growth, affection, 
      resolve (APGAR) index). The test scores were analyzed according to age, alcohol 
      use duration, and alcohol abstinence period. The Hamilton depression rating scale 
      (HAM-D) score and the family APGAR index score differentiated significantly 
      according to the age, alcohol use duration, and abstinence period of the LT 
      candidates. The patients with shorter alcohol use duration tended to have more 
      severe depressive symptoms and poorer family support. The younger patients showed 
      a significantly shorter abstinence period, more severe depression, and poorer 
      family functioning than older patients. The younger ALD patients and patients 
      with shorter alcohol use duration showed an increased severity of depression 
      before transplantation. They need more mental health care over time.
FAU - Chen, Yu-Ming
AU  - Chen YM
AUID- ORCID: 0000-0003-2609-2292
AD  - Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung 
      University College of Medicine, Kaohsiung 833, Taiwan.
FAU - Yu, Tien-Wei
AU  - Yu TW
AD  - Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung 
      University College of Medicine, Kaohsiung 833, Taiwan.
FAU - Wang, Chih-Chi
AU  - Wang CC
AD  - Liver Transplantation Center and Department of Surgery, Kaohsiung Chang Gung 
      Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, 
      Taiwan.
FAU - Huang, Kuang-Tzu
AU  - Huang KT
AUID- ORCID: 0000-0002-5902-3130
AD  - Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung 
      Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, 
      Taiwan.
FAU - Hsu, Li-Wen
AU  - Hsu LW
AUID- ORCID: 0000-0001-8825-3392
AD  - Liver Transplantation Center and Department of Surgery, Kaohsiung Chang Gung 
      Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, 
      Taiwan.
FAU - Lin, Chih-Che
AU  - Lin CC
AD  - Liver Transplantation Center and Department of Surgery, Kaohsiung Chang Gung 
      Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, 
      Taiwan.
FAU - Liu, Yueh-Wei
AU  - Liu YW
AD  - Liver Transplantation Center and Department of Surgery, Kaohsiung Chang Gung 
      Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, 
      Taiwan.
FAU - Li, Wei-Feng
AU  - Li WF
AD  - Liver Transplantation Center and Department of Surgery, Kaohsiung Chang Gung 
      Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, 
      Taiwan.
FAU - Chen, Chao-Long
AU  - Chen CL
AD  - Liver Transplantation Center and Department of Surgery, Kaohsiung Chang Gung 
      Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, 
      Taiwan.
FAU - Chen, Chien-Chih
AU  - Chen CC
AUID- ORCID: 0000-0003-0831-1199
AD  - Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung 
      University College of Medicine, Kaohsiung 833, Taiwan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20201123
PL  - Switzerland
TA  - Int J Environ Res Public Health
JT  - International journal of environmental research and public health
JID - 101238455
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - *Liver Diseases, Alcoholic/epidemiology/surgery
MH  - *Liver Transplantation/psychology
MH  - Male
MH  - Middle Aged
MH  - Recurrence
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Taiwan/epidemiology
PMC - PMC7700481
OTO - NOTNLM
OT  - alcoholic liver disease
OT  - depression
OT  - family function
OT  - liver transplantation
OT  - psychosocial evaluation
COIS- The authors declare that they have no conflicts of interest concerning this 
      article.
EDAT- 2020/11/27 06:00
MHDA- 2021/01/29 06:00
PMCR- 2020/11/01
CRDT- 2020/11/26 01:01
PHST- 2020/10/08 00:00 [received]
PHST- 2020/11/16 00:00 [revised]
PHST- 2020/11/19 00:00 [accepted]
PHST- 2020/11/26 01:01 [entrez]
PHST- 2020/11/27 06:00 [pubmed]
PHST- 2021/01/29 06:00 [medline]
PHST- 2020/11/01 00:00 [pmc-release]
AID - ijerph17228696 [pii]
AID - ijerph-17-08696 [pii]
AID - 10.3390/ijerph17228696 [doi]
PST - epublish
SO  - Int J Environ Res Public Health. 2020 Nov 23;17(22):8696. doi: 
      10.3390/ijerph17228696.