PMID- 33242378
OWN - NLM
STAT- MEDLINE
DCOM- 20220113
LR  - 20220113
IS  - 2151-4658 (Electronic)
IS  - 2151-464X (Linking)
VI  - 73
IP  - 12
DP  - 2021 Dec
TI  - Impact of Disease Activity on Physical Activity in Patients With Psoriatic 
      Arthritis.
PG  - 1834-1844
LID - 10.1002/acr.24422 [doi]
AB  - OBJECTIVE: The purpose of this study was to compare physical activity (PA) in a 
      group of patients with psoriatic arthritis (PsA) versus healthy controls and to 
      determine whether the mobility of these patients is affected by disease activity. 
      METHODS: A group of 52 patients with PsA and 53 controls were included in this 
      case-control study. PA was assessed by accelerometry in both groups and 
      additionally with the International Physical Activity Questionnaire (IPAQ) in 
      patients with PsA. Multiple regression analysis was used to compare PA between 
      groups and to determine the relationship between PA and PsA features, including 
      disease activity, as assessed by the 28-joint Disease Activity Score (DAS28) and 
      the Disease Activity Index for Psoriatic Arthritis (DAPSA) score. In a group of 
      36 patients, a test-retest study was carried out after 6 months. RESULTS: The 
      time engaged in moderate-to-vigorous physical activity (MVPA) per day, as 
      evaluated by accelerometry, and adjusted by confounders, proved similar in 
      patients with PsA and controls. In patients with PsA, disease activity was 
      inversely related to PA as assessed either by IPAQ or accelerometry. When PA was 
      compared in patients with PsA between the 2 visits, a significant difference in 
      the amount of time doing MVPA was found (42 +/- 33 versus 30 +/- 22 minutes/day; P = 
      0.004). Interestingly, in the test-retest study, variations in disease activity 
      over time based on DAPSA scores (r = -0.49, P = 0.002) and DAS28 using the 
      C-reactive protein level (r = -0.4, P = 0.017) were inversely correlated with 
      changes in PA, as determined by accelerometry. CONCLUSION: Patients with PsA show 
      levels of PA like healthy controls. In patients with PsA, disease activity and PA 
      are inversely correlated and the evaluation of PA by accelerometry is sensitive 
      to changes in disease activity.
CI  - (c) 2020, American College of Rheumatology.
FAU - Hernandez-Hernandez, Maria Vanesa
AU  - Hernandez-Hernandez MV
AD  - Hospital Universitario de Canarias, La Laguna, Spain.
FAU - Sanchez-Perez, Hiurma
AU  - Sanchez-Perez H
AD  - Hospital Universitario de Canarias, La Laguna, Spain.
FAU - Luna-Gomez, Cristina
AU  - Luna-Gomez C
AD  - Hospital Universitario Nuestra Senora de La Candelaria, Santa Cruz de Tenerife, 
      Spain.
FAU - Ferraz-Amaro, Ivan
AU  - Ferraz-Amaro I
AUID- ORCID: 0000-0003-0197-5267
AD  - Hospital Universitario de Canarias, La Laguna, Spain.
FAU - Diaz-Gonzalez, Federico
AU  - Diaz-Gonzalez F
AUID- ORCID: 0000-0002-4139-9295
AD  - Hospital Universitario de Canarias and Universidad de La Laguna, La Laguna, 
      Spain.
LA  - eng
GR  - European Regional Development Fund/
GR  - REUNINVES (Asociacion para la ayuda a la Investigacion del Hospital Universitario 
      de Canarias)/
GR  - PI12/02499/Instituto de Salud Carlos III/
GR  - PI15/01810/Instituto de Salud Carlos III/
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Arthritis Care Res (Hoboken)
JT  - Arthritis care & research
JID - 101518086
SB  - IM
MH  - Accelerometry
MH  - Adult
MH  - Aged
MH  - *Arthritis, Psoriatic
MH  - Case-Control Studies
MH  - *Exercise
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Patient Acuity
EDAT- 2020/11/27 06:00
MHDA- 2022/01/14 06:00
CRDT- 2020/11/26 17:06
PHST- 2020/02/04 00:00 [received]
PHST- 2020/08/11 00:00 [accepted]
PHST- 2020/11/27 06:00 [pubmed]
PHST- 2022/01/14 06:00 [medline]
PHST- 2020/11/26 17:06 [entrez]
AID - 10.1002/acr.24422 [doi]
PST - ppublish
SO  - Arthritis Care Res (Hoboken). 2021 Dec;73(12):1834-1844. doi: 10.1002/acr.24422.