PMID- 33253870
OWN - NLM
STAT- MEDLINE
DCOM- 20211011
LR  - 20220716
IS  - 1097-6809 (Electronic)
IS  - 0741-5214 (Print)
IS  - 0741-5214 (Linking)
VI  - 73
IP  - 6
DP  - 2021 Jun
TI  - Association between meeting daily step count goals with ambulatory function and 
      quality of life in patients with claudication.
PG  - 2105-2113
LID - S0741-5214(20)32479-4 [pii]
LID - 10.1016/j.jvs.2020.10.073 [doi]
AB  - OBJECTIVE: To determine (a) whether patients with peripheral artery disease (PAD) 
      who walked at least 7000 and 10,000 steps/day had better ambulatory function and 
      health-related quality of life (HRQoL) than patients who walked less than 7000 
      steps/day, and (b) whether differences in ambulatory function and HRQoL in 
      patients grouped according to these daily step count criteria persisted after 
      adjusting for covariates. METHODS: Two hundred forty-eight patients were assessed 
      on their daily ambulatory activity for 1 week with a step activity monitor, and 
      were grouped according to daily step count targets. Patients who took fewer than 
      7000 steps/day were included in group 1 (n = 153), those who took 7000 to 9999 
      steps/day were included in group 2 (n = 57), and patients who took at least 
      10,000 steps/day were included in group 3 (n = 38). Primary outcomes were the 
      6-minute walk distance (6MWD) and Walking Impairment Questionnaire (WIQ) distance 
      score, which is a disease-specific measurement of HRQoL. Patients were further 
      characterized on demographic variables, comorbid conditions, and cardiovascular 
      risk factors. RESULTS: The groups were significantly different on ankle-brachial 
      index (P = .02), and on the prevalence of hypertension (P = .04), diabetes (P < 
      .01), abdominal obesity (P < .01), arthritis (P = .04), and chronic obstructive 
      pulmonary disease (P < .01). Thus, these variables served as covariates in 
      adjusted analyses, along with age, weight, and sex. The 6MWD (mean +/- standard 
      deviation) was significantly different among the groups in unadjusted (P < .01) 
      and adjusted (P < .01) analyses (group 1, 313 +/- 90 m; group 2, 378 +/- 84 m; and 
      group 3, 414 +/- 77 m), with groups 2 and 3 having a higher 6MWD than group 1 (P < 
      .01). The WIQ distance score was significantly different among the groups in 
      unadjusted (P < .01) and adjusted (P < .01) analyses (group 1, 30 +/- 30%; group 2, 
      45 +/- 35%; and group 3, 47 +/- 34%), with groups 2 and 3 having higher WIQ distance 
      scores than group 1 (P < .01). CONCLUSIONS: Patients with PAD who walked more 
      than 7000 and 10,000 steps/day had greater ambulatory function and HRQoL than 
      patients who walked fewer than 7000 steps/day. Second, the greater ambulatory 
      function and HRQoL associated with walking 7000 and 10,000 steps/day persisted 
      after adjusting for covariates. This study provides preliminary evidence that 
      patients with PAD who walk more than 7000 steps/day have better ambulatory 
      function and HRQoL than patients below this threshold.
CI  - Copyright (c) 2020 Society for Vascular Surgery. Published by Elsevier Inc. All 
      rights reserved.
FAU - Gardner, Andrew W
AU  - Gardner AW
AD  - Department of Physical Medicine & Rehabilitation, Penn State College of Medicine, 
      Hershey, Pa; Reynolds Oklahoma Center on Aging, University of Oklahoma Health 
      Sciences Center, Oklahoma City, Okla. Electronic address: 
      agardner4@pennstatehealth.psu.edu.
FAU - Montgomery, Polly S
AU  - Montgomery PS
AD  - Department of Physical Medicine & Rehabilitation, Penn State College of Medicine, 
      Hershey, Pa; Reynolds Oklahoma Center on Aging, University of Oklahoma Health 
      Sciences Center, Oklahoma City, Okla.
FAU - Wang, Ming
AU  - Wang M
AD  - Department of Public Health Sciences, Penn State College of Medicine, Hershey, 
      Pa.
FAU - Shen, Biyi
AU  - Shen B
AD  - Department of Public Health Sciences, Penn State College of Medicine, Hershey, 
      Pa.
LA  - eng
GR  - M01 RR014467/RR/NCRR NIH HHS/United States
GR  - R01 AG024296/AG/NIA NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20201127
PL  - United States
TA  - J Vasc Surg
JT  - Journal of vascular surgery
JID - 8407742
SB  - IM
MH  - Actigraphy/instrumentation
MH  - Aged
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Exercise
MH  - Female
MH  - Fitness Trackers
MH  - Functional Status
MH  - Heart Disease Risk Factors
MH  - Humans
MH  - Intermittent Claudication/diagnosis/epidemiology/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - Peripheral Arterial Disease/diagnosis/epidemiology/*physiopathology
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Surveys and Questionnaires
MH  - Walk Test
MH  - *Walking
PMC - PMC8154704
MID - NIHMS1678382
OTO - NOTNLM
OT  - 6-minute walk
OT  - Exercise
OT  - Intermittent claudication
OT  - Physical activity
OT  - Steps
OT  - Treadmill test
EDAT- 2020/12/01 06:00
MHDA- 2021/10/12 06:00
PMCR- 2022/06/01
CRDT- 2020/11/30 20:11
PHST- 2020/04/28 00:00 [received]
PHST- 2020/10/18 00:00 [accepted]
PHST- 2020/12/01 06:00 [pubmed]
PHST- 2021/10/12 06:00 [medline]
PHST- 2020/11/30 20:11 [entrez]
PHST- 2022/06/01 00:00 [pmc-release]
AID - S0741-5214(20)32479-4 [pii]
AID - 10.1016/j.jvs.2020.10.073 [doi]
PST - ppublish
SO  - J Vasc Surg. 2021 Jun;73(6):2105-2113. doi: 10.1016/j.jvs.2020.10.073. Epub 2020 
      Nov 27.