PMID- 3325476 OWN - NLM STAT- MEDLINE DCOM- 19880407 LR - 20190828 IS - 0301-5564 (Print) IS - 0301-5564 (Linking) VI - 88 IP - 1 DP - 1987 TI - Localization of enkephalin- and neurotensin-like immunoreactivities in cat adrenal medulla. PG - 31-6 AB - Enkephalin (ENK)- and neurotensin (NT)-immunoreactivities (IR) were localized in cat adrenal medulla using immunocytochemistry. ENK was localized mainly in adrenaline cells, 70%-80% of which were heavily labelled. About 5%-10% of the noradrenaline cells were ENK-immunoreactive (IR). A dense network of ENK-IR nerves was localized among adrenaline cells. NT was localized only in the noradrenaline cells, 60%-70% of which were immunoreactive. NT- and ENK-IR were localized in separate noradrenaline cells. A dense network of NT-IR nerves was restricted among noradrenaline cells. The present findings confirm that ENK- and NT-like peptides are localized in separate adrenal medullary cells and demonstrate that also the preganglionic nerves are divided in subpopulations according to their neuropeptide content. These nerves have a selective localization among adrenaline and noradrenaline cells and may have physiological significance in the control of secretion of catecholamines and neuropeptides from adrenal medulla. FAU - Pelto-Huikko, M AU - Pelto-Huikko M AD - Department of Biomedical Sciences, University of Tampere, Finland. FAU - Salminen, T AU - Salminen T FAU - Hervonen, A AU - Hervonen A LA - eng PT - Journal Article PL - Germany TA - Histochemistry JT - Histochemistry JID - 0411300 RN - 0 (Enkephalins) RN - 39379-15-2 (Neurotensin) RN - X4W3ENH1CV (Norepinephrine) RN - YKH834O4BH (Epinephrine) SB - IM MH - Adrenal Medulla/*analysis MH - Animals MH - Cats MH - Enkephalins/*analysis MH - Epinephrine/metabolism MH - Histocytochemistry MH - Immunoenzyme Techniques MH - Male MH - Microscopy, Electron MH - Neurotensin/*analysis MH - Norepinephrine/metabolism EDAT- 1987/01/01 00:00 MHDA- 1987/01/01 00:01 CRDT- 1987/01/01 00:00 PHST- 1987/01/01 00:00 [pubmed] PHST- 1987/01/01 00:01 [medline] PHST- 1987/01/01 00:00 [entrez] AID - 10.1007/BF00490163 [doi] PST - ppublish SO - Histochemistry. 1987;88(1):31-6. doi: 10.1007/BF00490163.