PMID- 33263031
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231112
IS  - 2312-0541 (Print)
IS  - 2312-0541 (Electronic)
IS  - 2312-0541 (Linking)
VI  - 6
IP  - 4
DP  - 2020 Oct
TI  - Home invasive mechanical ventilation in Finland in 2015-2019.
LID - 00223-2020 [pii]
LID - 10.1183/23120541.00223-2020 [doi]
AB  - INTRODUCTION: The prevalence of long-term invasive mechanical ventilation via 
      tracheostomy in chronic respiratory insufficiency is largely unknown. We aimed to 
      clarify prevalence and aetiology of the use of home invasive mechanical 
      ventilation (HIMV) in Finland in 2015-2019. METHODS: Information on HIMV patients 
      was collected yearly from all Finnish Hospital District patient registries 
      between 1 January 2015 and 1 January 2019. Data included underlying diagnosis, 
      time from diagnosis to HIMV initiation, treatment length, mortality and basic 
      sociodemographic data. RESULTS: In 2015, we had 107 HIMV patients. During the 
      follow-up we received 34 new patients (24.1%) and 46 patients (32.6%) died. In 
      2019, we had 95 HIMV patients and the prevalence in Finland was 2.0 in 100 000. 
      The most common diagnoses were motor neurone disease (29.1%) and spinal cord 
      injuries (19.9%). Mean duration of HIMV among all patients on 1 January 2019 was 
      12.3 years and among deceased patients, 11.2 years. Treatment durations ranged 
      from 7.7 years for motor neurone disease patients to 47.3 years for post-polio 
      syndrome patients. Most patients (81.6%) used HIMV 24 h.day(-1). CONCLUSIONS: 
      HIMV is a rare, long-lasting treatment, most often used in chronic 
      hypoventilation caused by chronic neurological disease. Based on our 4 year 
      follow-up the prevalence of HIMV seems to be diminishing in Finland. Treatment 
      duration and survival vary greatly depending on the underlying diagnosis. Most of 
      the patients were totally dependent on HIMV, requiring 24-h care.
CI  - Copyright (c)ERS 2020.
FAU - Kotanen, Petra
AU  - Kotanen P
AUID- ORCID: 0000-0002-0470-2582
AD  - HUH Heart and Lung Center, Helsinki University Hospital and University of 
      Helsinki, Helsinki, Finland.
AD  - Doctoral Programme in Clinical Research, University of Helsinki, Helsinki, 
      Finland.
FAU - Kreivi, Hanna-Riikka
AU  - Kreivi HR
AUID- ORCID: 0000-0002-9361-8322
AD  - HUH Heart and Lung Center, Helsinki University Hospital and University of 
      Helsinki, Helsinki, Finland.
FAU - Vainionpaa, Aki
AU  - Vainionpaa A
AD  - Department of Rehabilitation, Seinajoki Central Hospital, Seinajoki, Finland.
FAU - Laaksovirta, Hannu
AU  - Laaksovirta H
AD  - HUH Neurocenter, Helsinki University Hospital and University of Helsinki, 
      Helsinki, Finland.
FAU - Brander, Pirkko
AU  - Brander P
AD  - HUH Heart and Lung Center, Helsinki University Hospital and University of 
      Helsinki, Helsinki, Finland.
FAU - Siirala, Waltteri
AU  - Siirala W
AD  - Dept of Anaesthesiology and Intensive Care, Turku University Hospital and 
      University of Turku, Turku, Finland.
LA  - eng
PT  - Journal Article
DEP - 20201110
PL  - England
TA  - ERJ Open Res
JT  - ERJ open research
JID - 101671641
PMC - PMC7682663
COIS- Conflict of interest: P. Kotanen reports grants from The Finnish 
      Anti-Tuberculosis Association, The Research Foundation of Pulmonary Diseases in 
      Finland, The Vaino and Laine Kivi Foundation, and The Governmental Subsidy for 
      Health Sciences Research, during the conduct of the study. Conflict of interest: 
      H-R. Kreivi has nothing to disclose. Conflict of interest: A. Vainionpaa has 
      nothing to disclose. Conflict of interest: H. Laaksovirta has nothing to 
      disclose. Conflict of interest: P. Brander has nothing to disclose. Conflict of 
      interest: W. Siirala has nothing to disclose.
EDAT- 2020/12/03 06:00
MHDA- 2020/12/03 06:01
PMCR- 2020/11/10
CRDT- 2020/12/02 05:34
PHST- 2020/04/27 00:00 [received]
PHST- 2020/09/01 00:00 [accepted]
PHST- 2020/12/02 05:34 [entrez]
PHST- 2020/12/03 06:00 [pubmed]
PHST- 2020/12/03 06:01 [medline]
PHST- 2020/11/10 00:00 [pmc-release]
AID - 00223-2020 [pii]
AID - 10.1183/23120541.00223-2020 [doi]
PST - epublish
SO  - ERJ Open Res. 2020 Nov 10;6(4):00223-2020. doi: 10.1183/23120541.00223-2020. 
      eCollection 2020 Oct.