PMID- 33266116
OWN - NLM
STAT- MEDLINE
DCOM- 20210308
LR  - 20210308
IS  - 1422-0067 (Electronic)
IS  - 1422-0067 (Linking)
VI  - 21
IP  - 23
DP  - 2020 Nov 30
TI  - Syringic Acid Alleviates Cesium-Induced Growth Defect in Arabidopsis.
LID - 10.3390/ijms21239116 [doi]
LID - 9116
AB  - Syringic acid, a phenolic compound, serves a variety of beneficial functions in 
      cells. Syringic acid increases in plants in response to cesium, and exogenous 
      application of syringic acid resulted in a significant attenuation of 
      cesium-induced growth defects in Arabidopsis. In addition, cesium or syringic 
      acid application to plants also resulted in increased lignin deposition in 
      interfascicular fibers. To better understand the role of lignin and syringic acid 
      in attenuating cesium-induced growth defects, two mutants for Arabidopsis REDUCED 
      EPIDERMAL FLUORESCENE 4 (REF4) and fourteen laccase mutants, some of which have 
      lower levels of lignin, were evaluated for their response to cesium. These 
      mutants responded differently to cesium stress, compared to control plants, and 
      the application of syringic acid alleviated cesium-induced growth defects in the 
      laccase mutants but not in the ref4 mutants. These findings imply that lignin 
      plays a role in cesium signaling but the attenuation of cesium stress defects by 
      syringic acid is mediated by regulatory components of lignin biosynthesis and not 
      lignin biosynthesis itself. In contrast, syringic acid did not alleviate any low 
      potassium-induced growth defects. Collectively, our findings provide the first 
      established link between lignin and cesium stress via syringic acid in plants.
FAU - Adams, Eri
AU  - Adams E
AUID- ORCID: 0000-0003-2182-5346
AD  - RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, 
      Yokohama, Kanagawa 230-0045, Japan.
FAU - Miyazaki, Takae
AU  - Miyazaki T
AD  - RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, 
      Yokohama, Kanagawa 230-0045, Japan.
FAU - Moon, Ju Yeon
AU  - Moon JY
AD  - RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, 
      Yokohama, Kanagawa 230-0045, Japan.
FAU - Sawada, Yuji
AU  - Sawada Y
AD  - RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, 
      Yokohama, Kanagawa 230-0045, Japan.
FAU - Sato, Muneo
AU  - Sato M
AD  - RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, 
      Yokohama, Kanagawa 230-0045, Japan.
FAU - Toyooka, Kiminori
AU  - Toyooka K
AUID- ORCID: 0000-0002-6414-5191
AD  - RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, 
      Yokohama, Kanagawa 230-0045, Japan.
FAU - Hirai, Masami Yokota
AU  - Hirai MY
AUID- ORCID: 0000-0003-0802-6208
AD  - RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, 
      Yokohama, Kanagawa 230-0045, Japan.
FAU - Shin, Ryoung
AU  - Shin R
AUID- ORCID: 0000-0003-4486-2852
AD  - RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, 
      Yokohama, Kanagawa 230-0045, Japan.
LA  - eng
PT  - Journal Article
DEP - 20201130
PL  - Switzerland
TA  - Int J Mol Sci
JT  - International journal of molecular sciences
JID - 101092791
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (Membrane Proteins)
RN  - 0 (REF4 protein, Arabidopsis)
RN  - 1KSV9V4Y4I (Cesium)
RN  - 632XD903SP (Gallic Acid)
RN  - 9005-53-2 (Lignin)
RN  - E390O181H5 (syringic acid)
RN  - RWP5GA015D (Potassium)
SB  - IM
MH  - Arabidopsis/*drug effects/*growth & development
MH  - Arabidopsis Proteins/genetics/metabolism
MH  - Cesium/*adverse effects
MH  - Gallic Acid/*analogs & derivatives/pharmacology
MH  - Lignin/metabolism
MH  - Membrane Proteins/genetics
MH  - Phenotype
MH  - Plant Development/*drug effects
MH  - Plant Shoots/drug effects/growth & development/metabolism
MH  - Potassium/metabolism
MH  - Stress, Physiological
PMC - PMC7730055
OTO - NOTNLM
OT  - REF4
OT  - cesium
OT  - lignin
OT  - syringic acid
COIS- The authors declare no conflict of interest.
EDAT- 2020/12/04 06:00
MHDA- 2021/03/09 06:00
PMCR- 2020/12/01
CRDT- 2020/12/03 01:05
PHST- 2020/10/30 00:00 [received]
PHST- 2020/11/26 00:00 [revised]
PHST- 2020/11/27 00:00 [accepted]
PHST- 2020/12/03 01:05 [entrez]
PHST- 2020/12/04 06:00 [pubmed]
PHST- 2021/03/09 06:00 [medline]
PHST- 2020/12/01 00:00 [pmc-release]
AID - ijms21239116 [pii]
AID - ijms-21-09116 [pii]
AID - 10.3390/ijms21239116 [doi]
PST - epublish
SO  - Int J Mol Sci. 2020 Nov 30;21(23):9116. doi: 10.3390/ijms21239116.