PMID- 33268200
OWN - NLM
STAT- MEDLINE
DCOM- 20210527
LR  - 20210527
IS  - 1873-3336 (Electronic)
IS  - 0304-3894 (Linking)
VI  - 406
DP  - 2021 Mar 15
TI  - Uptake, accumulation and associated cellular alterations of environmental samples 
      of microplastics in the seaworm Hediste diversicolor.
PG  - 124287
LID - S0304-3894(20)32277-9 [pii]
LID - 10.1016/j.jhazmat.2020.124287 [doi]
AB  - The ubiquitous distribution of microplastics (MPs) in the marine environment 
      raises global concern to understand their impact. Environmental MPs have been 
      shown to exhibit different physicochemical properties during their life cycles. 
      However, the body of knowledge regarding their accumulation and biological 
      effects is still significantly limited compared to manufactured MPs. To evaluate 
      the hazardous effects of a mixture of environmental MPs collected along the 
      Tunisian beaches, their accumulation and cellular effects were investigated in 
      Hediste diversicolor. MP sample was composed of polyethylene (PE), polyethylene 
      vinyl acetate (PEVA), low-density polyethylene (LDPE), high-density polyethylene 
      (HDPE), polypropylene (PP) and polyamide (PA) analyzed using Raman 
      microspectroscopy (RM). The concentrations of MPs in seaworm tissues increased 
      over time, following the order 1.2-0.45 microm > 3-1.2 microm > 100-3 microm. The ingestion 
      of MPs by H. diversicolor reduced their survival and growth, affected the 
      neuro-transmission and antioxidant pathways. Our data emphasised that the toxic 
      effects of environmental MPs were closely related to the exposure dose and 
      period. The results also demonstrated that the size distribution of MPs in 
      seaworms was mainly correlated with biochemical markers. This study highlights 
      the ecological risk in the ingestion and accumulation of environmental MPs by 
      biota that threatens their functional parameters.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Missawi, Omayma
AU  - Missawi O
AD  - University of Sousse, Laboratory of Biochemistry and Environmental Toxicology, 
      Higher Institute of Agronomy, Sousse, Tunisia; University of Monastir, Higher 
      Institute of Biotechnology of Monastir, Monastir, Tunisia.
FAU - Bousserrhine, Noureddine
AU  - Bousserrhine N
AD  - University Paris-Est Creteil, Laboratory of Water, Environment and Urban Systems, 
      Faculty of Science and Technology, Creteil Cedex, France.
FAU - Zitouni, Nesrine
AU  - Zitouni N
AD  - University of Sousse, Laboratory of Biochemistry and Environmental Toxicology, 
      Higher Institute of Agronomy, Sousse, Tunisia; University of Monastir, Higher 
      Institute of Biotechnology of Monastir, Monastir, Tunisia.
FAU - Maisano, Maria
AU  - Maisano M
AD  - University of Messina, Department of Chemical, Biological, Pharmaceutical and 
      Environmental Sciences, 98166 Messina, Italy.
FAU - Boughattas, Iteb
AU  - Boughattas I
AD  - University of Sousse, Laboratory of Biochemistry and Environmental Toxicology, 
      Higher Institute of Agronomy, Sousse, Tunisia.
FAU - De Marco, Giuseppe
AU  - De Marco G
AD  - University of Messina, Department of Chemical, Biological, Pharmaceutical and 
      Environmental Sciences, 98166 Messina, Italy.
FAU - Cappello, Tiziana
AU  - Cappello T
AD  - University of Messina, Department of Chemical, Biological, Pharmaceutical and 
      Environmental Sciences, 98166 Messina, Italy.
FAU - Belbekhouche, Sabrina
AU  - Belbekhouche S
AD  - CNRS, University of Paris-Est Creteil, Institute of Chemistry and Materials 
      Paris-Est ICMPE, UMR7182, 94320 Thiais, France.
FAU - Guerrouache, Mohamed
AU  - Guerrouache M
AD  - CNRS, University of Paris-Est Creteil, Institute of Chemistry and Materials 
      Paris-Est ICMPE, UMR7182, 94320 Thiais, France.
FAU - Alphonse, Vanessa
AU  - Alphonse V
AD  - University Paris-Est Creteil, Laboratory of Water, Environment and Urban Systems, 
      Faculty of Science and Technology, Creteil Cedex, France.
FAU - Banni, Mohamed
AU  - Banni M
AD  - University of Sousse, Laboratory of Biochemistry and Environmental Toxicology, 
      Higher Institute of Agronomy, Sousse, Tunisia; University of Monastir, Higher 
      Institute of Biotechnology of Monastir, Monastir, Tunisia. Electronic address: 
      m_banni@yahoo.fr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20201017
PL  - Netherlands
TA  - J Hazard Mater
JT  - Journal of hazardous materials
JID - 9422688
RN  - 0 (Microplastics)
RN  - 0 (Plastics)
RN  - 0 (Water Pollutants, Chemical)
RN  - 9002-88-4 (Polyethylene)
SB  - IM
MH  - Animals
MH  - Environmental Monitoring
MH  - Microplastics
MH  - Plastics/toxicity
MH  - *Polychaeta
MH  - Polyethylene/analysis
MH  - *Water Pollutants, Chemical/analysis/toxicity
OTO - NOTNLM
OT  - Accumulation
OT  - Cellular alterations
OT  - Environmental microplastics
OT  - Growth
OT  - Hediste diversicolor
EDAT- 2020/12/04 06:00
MHDA- 2021/05/28 06:00
CRDT- 2020/12/03 05:31
PHST- 2020/07/23 00:00 [received]
PHST- 2020/10/01 00:00 [revised]
PHST- 2020/10/13 00:00 [accepted]
PHST- 2020/12/04 06:00 [pubmed]
PHST- 2021/05/28 06:00 [medline]
PHST- 2020/12/03 05:31 [entrez]
AID - S0304-3894(20)32277-9 [pii]
AID - 10.1016/j.jhazmat.2020.124287 [doi]
PST - ppublish
SO  - J Hazard Mater. 2021 Mar 15;406:124287. doi: 10.1016/j.jhazmat.2020.124287. Epub 
      2020 Oct 17.