PMID- 33272894
OWN - NLM
STAT- MEDLINE
DCOM- 20210419
LR  - 20210419
IS  - 1525-5069 (Electronic)
IS  - 1525-5050 (Linking)
VI  - 114
IP  - Pt A
DP  - 2021 Jan
TI  - Electroclinical patterns in patients with nonconvulsive status epilepticus: 
      Etiology, treatment, and outcome.
PG  - 107611
LID - S1525-5050(20)30791-5 [pii]
LID - 10.1016/j.yebeh.2020.107611 [doi]
AB  - INTRODUCTION: This study investigated the clinical and electroencephalography 
      (EEG) features and prognostic factors of patients with nonconvulsive status 
      epilepticus (NCSE). MATERIALS AND METHODS: We retrospectively reviewed the 
      clinical files and EEG data of 45 (28 females, mean age 54 +/- 22.6 years) 
      consecutive patients with NCSE over a five-year period. An EEG interpreter who 
      was blinded to the clinical findings evaluated the EEGs according to the Salzburg 
      Consensus Criteria (SCC) for NCSE. Patient demographics, etiology, neuroimaging 
      and laboratory data, EEG features, treatment, and outcome measures were analyzed. 
      RESULTS: The most common etiology for NCSE was acute symptomatic etiologies 
      (57.8%) and cerebrovascular disease (48.9%). The majority (68.9%) of the patients 
      presented with new-onset status epilepticus (SE). NCSE was refractory to 
      treatment in 31.1% of patients. The most common status pattern consisted of 
      rhythmic delta/theta activity in 62.3% of EEGs. Twenty-five status patterns on 
      the EEGs were classified as definite, 30 as possible, and six as no NCSE 
      according to the SCC. The in-hospital mortality rate was high (33.3%) showing an 
      association with potentially fatal etiology, refractory SE, treatment with 
      continuous I.V. anesthetics and also the presence of multiple status patterns and 
      nonreactivity in EEGs (p < 0.05). CONCLUSIONS: The SCC for NCSE have high 
      diagnostic accuracy but do not affect prognosis. Potentially fatal etiology, 
      multiple status patterns on EEG and non-reactive EEGs may carry significantly 
      greater risk for short-term mortality.
CI  - Copyright (c) 2020 Elsevier Inc. All rights reserved.
FAU - Baysal-Kirac, Leyla
AU  - Baysal-Kirac L
AD  - Trakya University Hospital, Neurology and Clinical Neurophysiology Department, 
      22030 Balkan Yerleskesi, Edirne, Turkey. Electronic address: 
      baysalleyla@gmail.com.
FAU - Cakar, Merve Melodi
AU  - Cakar MM
AD  - Trakya University Hospital, Neurology and Clinical Neurophysiology Department, 
      22030 Balkan Yerleskesi, Edirne, Turkey.
FAU - Altiokka-Uzun, Gunes
AU  - Altiokka-Uzun G
AD  - Trakya University Hospital, Neurology and Clinical Neurophysiology Department, 
      22030 Balkan Yerleskesi, Edirne, Turkey.
FAU - Guncan, Zuhal
AU  - Guncan Z
AD  - Trakya University Hospital, Neurology and Clinical Neurophysiology Department, 
      22030 Balkan Yerleskesi, Edirne, Turkey.
FAU - Guldiken, Baburhan
AU  - Guldiken B
AD  - Trakya University Hospital, Neurology and Clinical Neurophysiology Department, 
      22030 Balkan Yerleskesi, Edirne, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20201201
PL  - United States
TA  - Epilepsy Behav
JT  - Epilepsy & behavior : E&B
JID - 100892858
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Cerebrovascular Disorders
MH  - Electroencephalography
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Prognosis
MH  - Retrospective Studies
MH  - *Status Epilepticus/diagnosis/epidemiology/etiology
OTO - NOTNLM
OT  - EEG
OT  - Epilepsy
OT  - Nonconvulsive status epilepticus
OT  - Salzburg Consensus Criteria
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2020/12/05 06:00
MHDA- 2021/04/20 06:00
CRDT- 2020/12/04 05:37
PHST- 2020/08/30 00:00 [received]
PHST- 2020/10/27 00:00 [revised]
PHST- 2020/10/28 00:00 [accepted]
PHST- 2020/12/05 06:00 [pubmed]
PHST- 2021/04/20 06:00 [medline]
PHST- 2020/12/04 05:37 [entrez]
AID - S1525-5050(20)30791-5 [pii]
AID - 10.1016/j.yebeh.2020.107611 [doi]
PST - ppublish
SO  - Epilepsy Behav. 2021 Jan;114(Pt A):107611. doi: 10.1016/j.yebeh.2020.107611. Epub 
      2020 Dec 1.