PMID- 33277018 OWN - NLM STAT- MEDLINE DCOM- 20210106 LR - 20221207 IS - 1879-1026 (Electronic) IS - 0048-9697 (Linking) VI - 757 DP - 2021 Feb 25 TI - How the recreational stimulant market has changed: Case study in Adelaide, Australia 2016-2019. PG - 143728 LID - S0048-9697(20)37259-4 [pii] LID - 10.1016/j.scitotenv.2020.143728 [doi] AB - The human consumption of stimulant drugs is known to increase over festive periods. In this work, four illicit stimulants: 3,4-methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxyamphetamine (MDA), cocaine and methamphetamine and three new psychoactive substances (NPS): ethylone, mephedrone and N-ethylpentylone were monitored in influent wastewater over the Christmas-New Year period in South Australia from 2016 to 2019 using liquid chromatography-mass spectrometry. The differences in Christmas - New Year consumption between years were evaluated and daily mass loads were compared to the average for that year to determine drug levels over the festive period. Although MDMA, MDA and cocaine showed year-on-year increases, the use over the New Year period was far higher than over the rest of the year, consistent with recreational drug use. These were also the drugs that were used predominantly on weekends during the year. Methamphetamine, which does not have a pattern of predominant weekend use, and the NPS showed variable trends. These results suggest that during holiday periods there are increases in the use of a limited set of drugs only and these can be predicted from patterns of use during the non-holiday periods. CI - Copyright (c) 2020 Elsevier B.V. All rights reserved. FAU - Bade, Richard AU - Bade R AD - University of South Australia, UniSA: Clinical and Health Sciences, Health and Biomedical Innovation, Adelaide 5000, South Australia, Australia. FAU - White, Jason M AU - White JM AD - University of South Australia, UniSA: Clinical and Health Sciences, Health and Biomedical Innovation, Adelaide 5000, South Australia, Australia. FAU - Gerber, Cobus AU - Gerber C AD - University of South Australia, UniSA: Clinical and Health Sciences, Health and Biomedical Innovation, Adelaide 5000, South Australia, Australia. Electronic address: cobus.gerber@unisa.edu.au. LA - eng PT - Journal Article DEP - 20201124 PL - Netherlands TA - Sci Total Environ JT - The Science of the total environment JID - 0330500 RN - 0 (Illicit Drugs) RN - 0 (Waste Water) RN - 0 (Water Pollutants, Chemical) SB - IM MH - Australia MH - Humans MH - *Illicit Drugs MH - South Australia MH - Substance Abuse Detection MH - *Substance-Related Disorders MH - Wastewater/analysis MH - *Water Pollutants, Chemical/analysis OTO - NOTNLM OT - Festivals OT - Illicit drugs OT - Liquid chromatography-mass spectrometry OT - New psychoactive substances OT - Wastewater-based epidemiology COIS- Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2020/12/06 06:00 MHDA- 2021/01/07 06:00 CRDT- 2020/12/05 05:24 PHST- 2020/09/13 00:00 [received] PHST- 2020/11/04 00:00 [revised] PHST- 2020/11/06 00:00 [accepted] PHST- 2020/12/06 06:00 [pubmed] PHST- 2021/01/07 06:00 [medline] PHST- 2020/12/05 05:24 [entrez] AID - S0048-9697(20)37259-4 [pii] AID - 10.1016/j.scitotenv.2020.143728 [doi] PST - ppublish SO - Sci Total Environ. 2021 Feb 25;757:143728. doi: 10.1016/j.scitotenv.2020.143728. Epub 2020 Nov 24.