PMID- 33280644 OWN - NLM STAT- MEDLINE DCOM- 20210611 LR - 20210611 IS - 1603-6824 (Electronic) IS - 0041-5782 (Linking) VI - 182 IP - 49 DP - 2020 Nov 30 TI - [Donor search for haematopoietic stem cell transplantation]. LID - V08200585 [pii] AB - Allogeneic haematopoietic stem cell transplantation is a clinical example of precision medicine, as one individual donor is selected for one individual patient based on genetic findings in the human leukocyte antigen (HLA) system. Unrelated donor search for Danish patients is based on an international collaboration between global registries hosting more than 37 million potential donors worldwide for patients in need. The implementation of next-generation sequencing technologies has been a revolution in donor registry typing due to more precise, detailed and cheaper HLA analyses, which is discussed in this review. FAU - Bruunsgaard, Helle AU - Bruunsgaard H AD - hellebruunsgaard@regionh.dk. FAU - Hauge, Anne Werner AU - Hauge AW LA - dan PT - Journal Article PT - Review PL - Denmark TA - Ugeskr Laeger JT - Ugeskrift for laeger JID - 0141730 RN - 0 (HLA Antigens) SB - IM MH - HLA Antigens/genetics MH - *Hematopoietic Stem Cell Transplantation MH - Histocompatibility Testing MH - Humans MH - Registries MH - Tissue Donors MH - Unrelated Donors EDAT- 2020/12/08 06:00 MHDA- 2021/06/12 06:00 CRDT- 2020/12/07 05:23 PHST- 2020/12/07 05:23 [entrez] PHST- 2020/12/08 06:00 [pubmed] PHST- 2021/06/12 06:00 [medline] AID - V08200585 [pii] PST - ppublish SO - Ugeskr Laeger. 2020 Nov 30;182(49):V08200585.