PMID- 33291620
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201226
IS  - 2073-4360 (Electronic)
IS  - 2073-4360 (Linking)
VI  - 12
IP  - 12
DP  - 2020 Dec 4
TI  - Production of Polyhydroxybutyrate (PHB) and Factors Impacting Its Chemical and 
      Mechanical Characteristics.
LID - 10.3390/polym12122908 [doi]
LID - 2908
AB  - Plastic pollution is fueling the grave environmental threats currently facing 
      humans, the animal kingdom, and the planet. The pursuit of renewable resourced 
      biodegradable materials commenced in the 1970s with the need for carbon neutral 
      fully sustainable products driving important progress in recent years. The 
      development of bioplastic materials is highlighted as imperative to the solutions 
      to our global environment challenges and to the restoration of the wellbeing of 
      our planet. Bio-based plastics are becoming increasingly sustainable and are 
      expected to substitute fossil-based plastics. Bioplastics currently include both, 
      nondegradable and biodegradable compositions, depending on factors including the 
      origins of production and post-use management and conditions. Among the most 
      promising materials being developed and evaluated is polyhydroxybutyrate (PHB), a 
      microbial bioprocessed polyester belonging to the polyhydroxyalkanoate (PHA) 
      family. This biocompatible and non-toxic polymer is biosynthesized and 
      accumulated by a number of specialized bacterial strains. The favorable 
      mechanical properties and amenability to biodegradation when exposed to certain 
      active biological environments, earmark PHB as a high potential replacement for 
      petrochemical based polymers such as ubiquitous high density polyethylene (HDPE). 
      To date, high production costs, minimal yields, production technology 
      complexities, and difficulties relating to downstream processing are limiting 
      factors for its progression and expansion in the marketplace. This review 
      examines the chemical, mechanical, thermal, and crystalline characteristics of 
      PHB, as well as various fermentation processing factors which influence the 
      properties of PHB materials.
FAU - McAdam, Blaithin
AU  - McAdam B
AD  - Athlone Institute of Technology, Dublin Road, N37HD68 Athlone, Ireland.
FAU - Brennan Fournet, Margaret
AU  - Brennan Fournet M
AD  - Athlone Institute of Technology, Dublin Road, N37HD68 Athlone, Ireland.
FAU - McDonald, Paul
AU  - McDonald P
AD  - Athlone Institute of Technology, Dublin Road, N37HD68 Athlone, Ireland.
FAU - Mojicevic, Marija
AU  - Mojicevic M
AUID- ORCID: 0000-0002-6094-8480
AD  - Athlone Institute of Technology, Dublin Road, N37HD68 Athlone, Ireland.
LA  - eng
GR  - 870292/Horizon 2020/
PT  - Journal Article
PT  - Review
DEP - 20201204
PL  - Switzerland
TA  - Polymers (Basel)
JT  - Polymers
JID - 101545357
PMC - PMC7761907
OTO - NOTNLM
OT  - PHB
OT  - bacterial fermentation
OT  - biodegradable
OT  - biosynthesis
OT  - biosynthetic polymers
OT  - polyhydroxyalkanoates
COIS- The authors declare no conflict of interest.
EDAT- 2020/12/10 06:00
MHDA- 2020/12/10 06:01
PMCR- 2020/12/04
CRDT- 2020/12/09 01:02
PHST- 2020/11/07 00:00 [received]
PHST- 2020/11/30 00:00 [revised]
PHST- 2020/12/01 00:00 [accepted]
PHST- 2020/12/09 01:02 [entrez]
PHST- 2020/12/10 06:00 [pubmed]
PHST- 2020/12/10 06:01 [medline]
PHST- 2020/12/04 00:00 [pmc-release]
AID - polym12122908 [pii]
AID - polymers-12-02908 [pii]
AID - 10.3390/polym12122908 [doi]
PST - epublish
SO  - Polymers (Basel). 2020 Dec 4;12(12):2908. doi: 10.3390/polym12122908.