PMID- 33291645 OWN - NLM STAT- MEDLINE DCOM- 20210409 LR - 20240330 IS - 2072-6643 (Electronic) IS - 2072-6643 (Linking) VI - 12 IP - 12 DP - 2020 Dec 4 TI - Lipidemic Profile Changes over a Two-Year Intervention Period: Who Benefited Most from the Feel4Diabetes Program? LID - 10.3390/nu12123736 [doi] LID - 3736 AB - Identification of participants' characteristics who benefited most from large community-based intervention studies may guide future prevention initiatives in order to maximize their effectiveness. The current study aimed to examine the socio-demographic, anthropometric, and behavioral characteristics, as well as the health and eating perceptions of those who improved their lipidemic profile, in the Feel4Diabetes early screening and prevention program. In the present analyses, 1773 adults from families at high risk for developing type 2 diabetes mellitus (T2DM) were enrolled, receiving either the standard care or the more intensive intervention, and 33.3-55.2% of them improved one or more of their lipidemic indices by >5%. Women, people living in Southeastern Europe, coming from two-parent families, having higher financial security, educational level and better diet quality were associated with a 27-64% higher likelihood for benefiting from the program regarding one or more of their lipidemic profile indices. Participants who were overweight or obese (especially with central obesity), employed, with prolonged sedentary behavior, prone to emotional eating and perceiving their weight status as lower than their actual weight were 24-43% less likely to have benefited. These findings should guide future interventions, prioritizing regions in greater need, and being tailor-made to specific population characteristics in order to further improve their effectiveness. FAU - Karatzi, Kalliopi AU - Karatzi K AUID- ORCID: 0000-0001-5453-898X AD - Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17671 Athens, Greece. FAU - Moschonis, George AU - Moschonis G AUID- ORCID: 0000-0003-3009-6675 AD - Department of Dietetics, Nutrition and Sport, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC 3086, Australia. FAU - Botsi, Eirini AU - Botsi E AUID- ORCID: 0000-0002-6475-3357 AD - Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17671 Athens, Greece. FAU - Liatis, Stavros AU - Liatis S AD - National and Kapodistrian University of Athens Medical School, 11527 Athens, Greece. FAU - Tsochev, Kaloyan AU - Tsochev K AD - Department of Paediatrics, Medical University Varna, 9002 Varna, Bulgaria. FAU - De Miguel-Etayo, Pilar AU - De Miguel-Etayo P AUID- ORCID: 0000-0001-6173-5850 AD - Growth, Exercise, Nutrition and Development (GENUD) Research Group, Instituto Agroalimentario de Aragon (IA2), Instituto de Investigacion Sanitaria de Aragon (IIS Aragon), Universidad de Zaragoza, 50009 Zaragoza, Spain. AD - Centro de Investigacion Biomedica en Red Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain. FAU - Kivela, Jemina AU - Kivela J AUID- ORCID: 0000-0002-0605-8778 AD - Department of Public Health Solutions, Finnish Institute for Health and Welfare, 00271 Helsinki, Finland. FAU - Wikstrom, Katja AU - Wikstrom K AD - Department of Public Health Solutions, Finnish Institute for Health and Welfare, 00271 Helsinki, Finland. FAU - Dimova, Roumyana AU - Dimova R AD - Department of Diabetology, Clinical Center of Endocrinology, Medical University Sofia, 1431 Sofia, Bulgaria. FAU - Antal, Emese AU - Antal E AD - Hungarian Society of Nutrition, 1088 Budapest, Hungary. FAU - Lamiquiz-Moneo, Itziar AU - Lamiquiz-Moneo I AD - Hospital Universitario Miguel Servet, Instituto de Investigacion Sanitaria Aragon (IIS Aragon), CIBERCV, Universidad de Zaragoza, 50009 Zaragoza, Spain. FAU - Rurik, Imre AU - Rurik I AUID- ORCID: 0000-0003-2818-8714 AD - Hungarian Society of Nutrition, 1088 Budapest, Hungary. FAU - Cardon, Greet AU - Cardon G AUID- ORCID: 0000-0003-4983-6557 AD - Department of Movement and Sports Sciences, Faculty of Medicine and Health Sciences, Ghent University, 9000 Gent, Belgium. FAU - Iotova, Violeta AU - Iotova V AD - Department of Paediatrics, Medical University Varna, 9002 Varna, Bulgaria. FAU - Makrilakis, Konstantinos AU - Makrilakis K AUID- ORCID: 0000-0002-4160-0577 AD - National and Kapodistrian University of Athens Medical School, 11527 Athens, Greece. FAU - Manios, Yannis AU - Manios Y AUID- ORCID: 0000-0001-6486-114X AD - Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17671 Athens, Greece. FAU - On Behalf Of The Feel Diabetes-Study Group AU - On Behalf Of The Feel Diabetes-Study Group LA - eng GR - 643708/Horizon 2020/ PT - Journal Article PT - Randomized Controlled Trial DEP - 20201204 PL - Switzerland TA - Nutrients JT - Nutrients JID - 101521595 RN - 0 (Lipids) SB - IM MH - Adult MH - Body Weight MH - Diabetes Mellitus, Type 2/epidemiology/*prevention & control MH - Diet MH - Educational Status MH - Europe/epidemiology MH - Female MH - *Health Behavior MH - Health Promotion/methods MH - Humans MH - *Life Style MH - Lipids/*blood MH - Male MH - Mass Screening/methods MH - Middle Aged MH - Obesity/blood MH - Overweight/blood MH - Preventive Health Services/methods PMC - PMC7761911 OTO - NOTNLM OT - Feel4Diabetes study OT - lifestyle intervention OT - lipidemic profile COIS- The authors declare no conflict of interest. EDAT- 2020/12/10 06:00 MHDA- 2021/04/10 06:00 PMCR- 2020/12/04 CRDT- 2020/12/09 01:02 PHST- 2020/11/18 00:00 [received] PHST- 2020/11/30 00:00 [accepted] PHST- 2020/12/09 01:02 [entrez] PHST- 2020/12/10 06:00 [pubmed] PHST- 2021/04/10 06:00 [medline] PHST- 2020/12/04 00:00 [pmc-release] AID - nu12123736 [pii] AID - nutrients-12-03736 [pii] AID - 10.3390/nu12123736 [doi] PST - epublish SO - Nutrients. 2020 Dec 4;12(12):3736. doi: 10.3390/nu12123736.