PMID- 33293983
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240330
IS  - 1728-869X (Print)
IS  - 2226-5104 (Electronic)
IS  - 1728-869X (Linking)
VI  - 19
IP  - 1
DP  - 2021 Jan
TI  - Effect of blood flow restriction during low-intensity resistance training on bone 
      markers and physical functions in postmenopausal women.
PG  - 57-65
LID - 10.1016/j.jesf.2020.09.001 [doi]
AB  - BACKGROUND: The aim of this study was to investigate the effects of 12-week low 
      intensity resistance training (RT) with blood flow restriction on bone mineral 
      density (BMD), bone turnover markers (BTM), physical functions, and blood lactate 
      concentration in postmenopausal women with osteoporosis or osteopenia. METHODS: 
      26 study participants (56 +/- 1.8yrs, T-score: -2.5 +/- 0.7) were randomly assigned 
      into Moderate to High-Intensity RT (MHIRT, n = 7), BFR combined with 
      Low-Intensity RT (LIBFR, n = 7), Low-Intensity RT (LIRT, n = 6), or Control group 
      (CON, n = 6). Exercise group performed leg press, leg extension, biceps curl, and 
      triceps extension 3 times a week for 12 weeks. Training intensity were set at 60% 
      of 1-repetition maximum (1-RM) for MHIRT, and at 30% of 1-RM for LIBFR and LIRT, 
      and reset every 4 weeks for increasing intensity. RESULTS: Lower, and upper limb 
      1-RM only increased in MHIRT (65%, p < 0.001), and LIBFR (40%, p < 0.05), while 
      LIRT only showed increment on lower limb 1-RM (28%, p < 0.05). All exercise 
      groups demonstrated significant increment on blood lactate concentration after 
      training session (p < 0.001). However, LIBFR showed 2.7 folds higher increment 
      than LIRT (p < 0.001). Although no changes were observed in MHIRT, LIBFR, and 
      LIRT, CON showed significant decrease in BMD (p < 0.05). While, LIRT showed no 
      responses on BTM, LIBFR significantly increased bone formation markers (P1NP) 
      about 7.05 ng/ml (p < 0.05). Lastly, balance improvement was only found in MHIRT, 
      and LIBFR (p < 0.05). CONCLUSION: 12-week LIBFR can be implied as a safe, and 
      effective method to improve muscle strength, P1NP, and balance similar to MHIRT 
      in postmenopausal women with osteoporosis or osteopenia.
CI  - (c) 2020 The Society of Chinese Scholars on Exercise Physiology and Fitness. 
      Published by Elsevier (Singapore) Pte Ltd.
FAU - Linero, Christian
AU  - Linero C
AD  - Department of Sport and Health Sciences, Kyungsung University, Busan, South 
      Korea.
FAU - Choi, Seung-Jun
AU  - Choi SJ
AD  - Department of Sport and Health Sciences, Kyungsung University, Busan, South 
      Korea.
LA  - eng
PT  - Journal Article
DEP - 20200925
PL  - Singapore
TA  - J Exerc Sci Fit
JT  - Journal of exercise science and fitness
JID - 101198241
PMC - PMC7683332
OTO - NOTNLM
OT  - Blood flow restriction
OT  - Bone resorption
OT  - Menopause
OT  - Resistance training
COIS- The authors have no conflicts of interest relevant to this article.
EDAT- 2020/12/10 06:00
MHDA- 2020/12/10 06:01
PMCR- 2020/09/25
CRDT- 2020/12/09 06:13
PHST- 2020/06/04 00:00 [received]
PHST- 2020/07/20 00:00 [revised]
PHST- 2020/09/11 00:00 [accepted]
PHST- 2020/12/09 06:13 [entrez]
PHST- 2020/12/10 06:00 [pubmed]
PHST- 2020/12/10 06:01 [medline]
PHST- 2020/09/25 00:00 [pmc-release]
AID - S1728-869X(20)30303-8 [pii]
AID - 10.1016/j.jesf.2020.09.001 [doi]
PST - ppublish
SO  - J Exerc Sci Fit. 2021 Jan;19(1):57-65. doi: 10.1016/j.jesf.2020.09.001. Epub 2020 
      Sep 25.