PMID- 33295217
OWN - NLM
STAT- MEDLINE
DCOM- 20211123
LR  - 20220428
IS  - 1724-6016 (Electronic)
IS  - 1120-6721 (Linking)
VI  - 31
IP  - 6
DP  - 2021 Nov
TI  - Refractive outcomes of high-magnitude astigmatism correction using femtosecond 
      LASIK versus transepithelial PRK.
PG  - 2923-2931
LID - 10.1177/1120672120978885 [doi]
AB  - PURPOSE: To compare the outcomes of femtosecond laser assisted in situ 
      keratomileusis (FS-LASIK) with transepithelial photorefractive keratectomy 
      (T-PRK) for the correction of high-grade astigmatism. METHODS: Medical records of 
      patients with astigmatism of 2 diopters (D) or higher, who were treated with 
      FS-LASIK or T-PRK in 2013 through 2014 at a private practice laser clinic, were 
      retrospectively analyzed. Efficacy, safety, predictability and vector analysis of 
      astigmatism correction were compared between the treatment groups. RESULTS: The 
      study included 93 eyes treated with FS-LASIK and 186 eyes treated with T-PRK. No 
      significant differences in postoperative spherical equivalent (-0.10 +/- 0.7 D and 
      -0.11 +/- 0.7 D, respectively, p = 0.958) and postoperative refractive astigmatism 
      (0.79 +/- 0.54 D and 0.82 +/- 0.63 D, respectively, p = 0.685) were demonstrated. A 
      significant advantage of FS-LASIK over T-PRK was seen for the efficacy 
      (1.00 +/- 0.18 and 0.86 +/- 0.22, respectively, p < 0.001) and safety (1.03 +/- 0.17 
      and 0.89 +/- 0.21, respectively, p < 0.001) indices. Results remain statistically 
      significant in a multivariate analysis model. Vector analysis for the astigmatism 
      correction showed no significant difference between the surgery methods in the 
      surgically induced astigmatism, difference vector, correction index and index of 
      success. CONCLUSION: Both procedures demonstrated desirable post-operative SE 
      outcomes for high-grade astigmatism correction. However, FS-LASIK achieved better 
      results than T-PRK in the efficacy and safety parameters.
FAU - Reitblat, Olga
AU  - Reitblat O
AUID- ORCID: 0000-0002-8417-4440
AD  - Department of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.
AD  - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Gershoni, Assaf
AU  - Gershoni A
AD  - Department of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.
AD  - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
AD  - Assuta Optic Laser Center, Assuta Medical Center, Tel Aviv, Israel.
FAU - Mimouni, Michael
AU  - Mimouni M
AUID- ORCID: 0000-0002-4661-0993
AD  - Department of Ophthalmology, Rambam Health Care Campus, Haifa, Israel.
AD  - Ruth and Bruce Faculty of Medicine, Technion-Israel Institute of Technology, 
      Haifa, Israel.
FAU - Vainer, Igor
AU  - Vainer I
AD  - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Livny, Eitan
AU  - Livny E
AUID- ORCID: 0000-0002-3398-5905
AD  - Department of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.
AD  - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
AD  - Assuta Optic Laser Center, Assuta Medical Center, Tel Aviv, Israel.
FAU - Nahum, Yoav
AU  - Nahum Y
AUID- ORCID: 0000-0002-0246-4787
AD  - Department of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.
AD  - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
AD  - Assuta Optic Laser Center, Assuta Medical Center, Tel Aviv, Israel.
FAU - Segev, Fani
AU  - Segev F
AD  - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
AD  - Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel.
FAU - Bahar, Irit
AU  - Bahar I
AUID- ORCID: 0000-0003-2008-0717
AD  - Department of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.
AD  - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
AD  - Assuta Optic Laser Center, Assuta Medical Center, Tel Aviv, Israel.
LA  - eng
PT  - Journal Article
DEP - 20201209
PL  - United States
TA  - Eur J Ophthalmol
JT  - European journal of ophthalmology
JID - 9110772
SB  - IM
MH  - *Astigmatism/surgery
MH  - Cornea
MH  - Humans
MH  - *Keratomileusis, Laser In Situ
MH  - Lasers, Excimer/therapeutic use
MH  - *Photorefractive Keratectomy
MH  - Refraction, Ocular
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Visual Acuity
OTO - NOTNLM
OT  - Refractive surgery
OT  - astigmatism
OT  - femtosecond laser assisted in situ keratomileusis
OT  - high-grade astigmatism
OT  - transepithelial photorefractive keratectomy
EDAT- 2020/12/10 06:00
MHDA- 2021/11/24 06:00
CRDT- 2020/12/09 08:37
PHST- 2020/12/10 06:00 [pubmed]
PHST- 2021/11/24 06:00 [medline]
PHST- 2020/12/09 08:37 [entrez]
AID - 10.1177/1120672120978885 [doi]
PST - ppublish
SO  - Eur J Ophthalmol. 2021 Nov;31(6):2923-2931. doi: 10.1177/1120672120978885. Epub 
      2020 Dec 9.