PMID- 33296012
OWN - NLM
STAT- MEDLINE
DCOM- 20210427
LR  - 20210427
IS  - 1432-1289 (Electronic)
IS  - 0020-9554 (Linking)
VI  - 62
IP  - 4
DP  - 2021 Apr
TI  - [A 3-week history of intestinal symptoms in a 67-year-old male patient with 
      chronic arthralgia].
PG  - 433-440
LID - 10.1007/s00108-020-00916-8 [doi]
AB  - Whipple disease is an infection caused by the bacterium Tropheryma whipplei. Due 
      to its unspecific clinical symptoms, it is difficult to diagnose and often 
      remains undetected for a long time. The case of a patient who presented with 
      acute intestinal symptoms to the authors' department is reported. The diagnosis 
      of classic Whipple disease was established. The symptoms subsided under 
      antibiotic therapy. Complications in the form of immune reconstitution 
      inflammatory syndrome (IRIS) occurred, requiring immunosuppressive treatment.
FAU - Keim, V J
AU  - Keim VJ
AD  - Medizinische Klinik 1, ViDia Christliche Kliniken Karlsruhe, Karlsruhe, 
      Deutschland. victor.keim@klinikum-karlsruhe.de.
AD  - Medizinische Klinik II, Stadtisches Klinikum Karlsruhe, Moltkestrasse 90, 
      Karlsruhe, 76133, Deutschland. victor.keim@klinikum-karlsruhe.de.
FAU - Zachmann, G
AU  - Zachmann G
AD  - Medizinische Klinik 1, ViDia Christliche Kliniken Karlsruhe, Karlsruhe, 
      Deutschland.
FAU - Faller, G
AU  - Faller G
AD  - Pathologisches Institut, ViDia Christliche Kliniken Karlsruhe, Karlsruhe, 
      Deutschland.
FAU - Zopf, T
AU  - Zopf T
AD  - Medizinische Klinik 1, ViDia Christliche Kliniken Karlsruhe, Karlsruhe, 
      Deutschland.
LA  - ger
PT  - Case Reports
PT  - Journal Article
TT  - Seit 3 Wochen bestehende intestinale Beschwerden bei einem 67-jahrigen Patienten 
      mit chronischen Arthralgien.
DEP - 20201209
PL  - Germany
TA  - Internist (Berl)
JT  - Der Internist
JID - 0264620
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Immunosuppressive Agents)
SB  - IM
MH  - Aged
MH  - Anti-Bacterial Agents/therapeutic use
MH  - Arthralgia/diagnosis/drug therapy/etiology
MH  - Humans
MH  - *Immune Reconstitution Inflammatory Syndrome/drug therapy
MH  - Immunosuppressive Agents
MH  - Male
MH  - Tropheryma
MH  - *Whipple Disease/diagnosis/drug therapy
OTO - NOTNLM
OT  - Arthralgia
OT  - Diarrhea
OT  - Immune reconstitution inflammatory syndrome
OT  - Tropheryma whipplei
OT  - Whipple disease
EDAT- 2020/12/10 06:00
MHDA- 2021/04/28 06:00
CRDT- 2020/12/09 12:13
PHST- 2020/11/18 00:00 [accepted]
PHST- 2020/12/10 06:00 [pubmed]
PHST- 2021/04/28 06:00 [medline]
PHST- 2020/12/09 12:13 [entrez]
AID - 10.1007/s00108-020-00916-8 [pii]
AID - 10.1007/s00108-020-00916-8 [doi]
PST - ppublish
SO  - Internist (Berl). 2021 Apr;62(4):433-440. doi: 10.1007/s00108-020-00916-8. Epub 
      2020 Dec 9.