PMID- 33303173
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20201214
LR  - 20201214
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 223
IP  - Pt 1
DP  - 2021 Feb 1
TI  - A novel"turn-off"fluorescence assay based on acid-copper nanoclusters in deep 
      eutectic solvent micelles for co-aggregation inducing fluorescence enhancement 
      and its application.
PG  - 121731
LID - S0039-9140(20)31022-5 [pii]
LID - 10.1016/j.talanta.2020.121731 [doi]
AB  - As mixtures, deep eutectic solvent (DES) is designability. By adjusting the long 
      alkyl chain hydrogen bond acceptors (HBAs) or hydrogen bond donors (HBDs), the 
      DES displays surfactant characteristics and can form micelles. Hence, a novel, 
      simple, facile and green natural organic acids capped copper nanoclusters 
      (Aci-CuNCs) was synthesized and the spectrum behavior of Aci-CuNCs in DES 
      micelles was researched. It was found that the surfactant-like DES can form 
      micellar co-aggregation with Aci-CuNCs, resulting in the fluorescence (FL) 
      intensive of Aci-CuNCs increase. Corresponding performance of spectral properties 
      of Aci-CuNCs in DES medium were systematically studied by fourier transform 
      infrared spectrometer, 3D FL spectroscopy, FL emission/excitation spectra, 
      ultraviolet absorption spectroscopy. In the mechanism exploration part, on the 
      one hand, the existence of micellar co-aggregation was confirmed by the 
      conductivity, the mass effect of DES, dynamic light scattering and transmission 
      electron microscopy. On the other hand, the influence of different kinds of DESs 
      (types of HBAs/HBDs, molar ratio) and some possible factors (ionic strength and 
      temperature) were discussed in detail to investigate the main driving forces for 
      the formation of micellar co-aggregates. The results of mechanism exploration 
      prove that the long alkyl chain of DES is amphiphilic which can form micellar 
      co-aggregation with Aci-CuNCs through hydrogen bonding. The DES micelle provides 
      Aci-CuNCs with a relatively stable and closed micro-environment which can 
      effectively prevent collisions with water molecules and weakening of fluorescence 
      intensity. On the basic of the above research, a "turn-off" fluorimetric method 
      based on Aci-CuNCs in DES medium was applied for the determination of Fe(3+). 
      Under the optimum conditions, the assay worked in the Fe(3+) concentration ranges 
      from 1 to -20 muM and had a detection limit of 0.0374 muM. Method validation study 
      illustrates the proposed system can provide a good accuracy, repeatability and 
      stability conditions. Furthermore, the real sample analysis result demonstrates 
      that no obvious matrix effect is found. As a consequence, the FL assays 
      (Aci-CuNCs-based DES) composed of natural organic acid capped CuNCs and green 
      solvent DES provides a simple, gentle and environmentally friendly method for the 
      detection of iron ions.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Chen, Jing
AU  - Chen J
AD  - State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry 
      and Chemical Engineering, Hunan University, Changsha, 410082, PR China; College 
      of Material and Chemical Engineering, Tongren University, Tongren, 554300, PR 
      China.
FAU - Wang, Yuzhi
AU  - Wang Y
AD  - State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry 
      and Chemical Engineering, Hunan University, Changsha, 410082, PR China. 
      Electronic address: wyzss@hnu.edu.cn.
FAU - Wei, Xiaoxiao
AU  - Wei X
AD  - State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry 
      and Chemical Engineering, Hunan University, Changsha, 410082, PR China.
FAU - Liu, Ziwei
AU  - Liu Z
AD  - State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry 
      and Chemical Engineering, Hunan University, Changsha, 410082, PR China.
FAU - Xu, Fangting
AU  - Xu F
AD  - State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry 
      and Chemical Engineering, Hunan University, Changsha, 410082, PR China.
FAU - Li, Heqiong
AU  - Li H
AD  - State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry 
      and Chemical Engineering, Hunan University, Changsha, 410082, PR China.
FAU - He, Xiyan
AU  - He X
AD  - State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry 
      and Chemical Engineering, Hunan University, Changsha, 410082, PR China.
LA  - eng
PT  - Journal Article
DEP - 20201006
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
SB  - IM
OTO - NOTNLM
OT  - Co-aggregation
OT  - Deep eutectic solvent
OT  - Fe(3+)
OT  - Fluorescence
OT  - Micelle
EDAT- 2020/12/12 06:00
MHDA- 2020/12/12 06:01
CRDT- 2020/12/11 05:39
PHST- 2020/08/04 00:00 [received]
PHST- 2020/09/29 00:00 [revised]
PHST- 2020/10/02 00:00 [accepted]
PHST- 2020/12/11 05:39 [entrez]
PHST- 2020/12/12 06:00 [pubmed]
PHST- 2020/12/12 06:01 [medline]
AID - S0039-9140(20)31022-5 [pii]
AID - 10.1016/j.talanta.2020.121731 [doi]
PST - ppublish
SO  - Talanta. 2021 Feb 1;223(Pt 1):121731. doi: 10.1016/j.talanta.2020.121731. Epub 
      2020 Oct 6.