PMID- 33305336 OWN - NLM STAT- MEDLINE DCOM- 20211015 LR - 20220218 IS - 1437-2320 (Electronic) IS - 0344-5607 (Print) IS - 0344-5607 (Linking) VI - 44 IP - 5 DP - 2021 Oct TI - Influence of dynamic preoperative body mass index changes on patient-reported outcomes after surgery for degenerative lumbar spine disease. PG - 2689-2696 LID - 10.1007/s10143-020-01454-5 [doi] AB - Psychological factors demonstrably and often massively influence outcomes of degenerative spine surgery, and one could hypothesize that preoperative weight loss may correlate with motivation and lifestyle adjustment, thus leading to potentially enhanced outcomes. We aimed to evaluate the effect of preoperative weight loss or gain, respectively, on patient-reported outcomes after lumbar spine surgery. Weight loss was defined as a BMI decrease of /= 0.5 kg/m(2) in the same time period, respectively. The primary endpoint was set as the achievement of the minimum clinically important difference (MCID) in the ODI at 1 or 2 years postoperatively. A total of 154 patients were included. Weight loss (odds ratio (OR): 1.18, 95% confidence interval (CI): 0.52 to 2.80) and weight gain (OR: 1.03, 95% CI: 0.43 to 2.55) showed no significant influence on MCID achievement for ODI compared to a stable BMI. The same results were observed when analysing long-term NRS-BP and NRS-LP. Regression analysis showed no correlation between BMI change and PROM change scores for any of the three PROMs. Adjustment for age and gender did not alter results. Our findings suggest that both preoperative weight loss and weight gain may have no measurable effect on long-term postoperative outcome compared to a stable BMI. Weight loss preoperatively-as a potential surrogate sign of patient motivation and lifestyle change-may thus not influence postoperative outcomes. CI - (c) 2020. The Author(s). FAU - Siccoli, Alessandro AU - Siccoli A AD - Department of Neurosurgery, Bergman Clinics, Amsterdam, The Netherlands. AD - Faculty of Medicine, University of Zurich, Zurich, Switzerland. FAU - Schroder, Marc L AU - Schroder ML AD - Department of Neurosurgery, Bergman Clinics, Amsterdam, The Netherlands. FAU - Staartjes, Victor E AU - Staartjes VE AUID- ORCID: 0000-0003-1039-2098 AD - Department of Neurosurgery, Bergman Clinics, Amsterdam, The Netherlands. victor.staartjes@gmail.com. AD - Department of Neurosurgery, Clinical Neuroscience Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland. victor.staartjes@gmail.com. AD - Bergman Clinics, Naarden, Rijksweg 69, 1411, GE, Naarden, The Netherlands. victor.staartjes@gmail.com. LA - eng PT - Journal Article DEP - 20201211 PL - Germany TA - Neurosurg Rev JT - Neurosurgical review JID - 7908181 SB - IM MH - Body Mass Index MH - Disability Evaluation MH - Humans MH - Lumbar Vertebrae/surgery MH - Patient Reported Outcome Measures MH - Postoperative Period MH - *Spinal Diseases/surgery MH - Treatment Outcome PMC - PMC8490227 OTO - NOTNLM OT - Obesity OT - Outcome OT - Overweight OT - Weight gain OT - Weight loss COIS- The authors declare that they have no conflict of interest. EDAT- 2020/12/12 06:00 MHDA- 2021/10/16 06:00 PMCR- 2020/12/11 CRDT- 2020/12/11 06:06 PHST- 2020/08/28 00:00 [received] PHST- 2020/12/02 00:00 [accepted] PHST- 2020/11/03 00:00 [revised] PHST- 2020/12/12 06:00 [pubmed] PHST- 2021/10/16 06:00 [medline] PHST- 2020/12/11 06:06 [entrez] PHST- 2020/12/11 00:00 [pmc-release] AID - 10.1007/s10143-020-01454-5 [pii] AID - 1454 [pii] AID - 10.1007/s10143-020-01454-5 [doi] PST - ppublish SO - Neurosurg Rev. 2021 Oct;44(5):2689-2696. doi: 10.1007/s10143-020-01454-5. Epub 2020 Dec 11.