PMID- 33307487
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20210514
IS  - 1878-0180 (Electronic)
IS  - 1878-0180 (Linking)
VI  - 115
DP  - 2021 Mar
TI  - Compressive anisotropy of sheet and strut based porous Ti-6Al-4V scaffolds.
PG  - 104243
LID - S1751-6161(20)30782-7 [pii]
LID - 10.1016/j.jmbbm.2020.104243 [doi]
AB  - Porous metallic scaffolds show promise in orthopedic applications due to 
      favorable mechanical and biological properties. In vivo stress conditions on 
      orthopedic implants are complex, often including multiaxial loading across off 
      axis orientations. In this study, unit cell orientation was rotated in the XZ 
      plane of a strut-based architecture, Diamond Crystal, and two sheet-based, triply 
      periodic minimal surface (TPMS) architectures, Schwartz D and Gyroid. Sheet-based 
      architectures exhibited higher peak compressive strength, yield strength and 
      strain at peak stress than the strut-based architecture. All three topologies 
      demonstrated an orientational dependence in mechanical properties. There was a 
      greater degree of anisotropy (49%) in strut-based architecture than in either 
      TPMS architectures (18-21%). These results support the superior strength and 
      advantageous isotropic mechanical properties of sheet-based TPMS architectures 
      relative to strut-based architectures, as well as highlighting the importance of 
      considering anisotropic properties of lattice scaffolds for use in tissue 
      engineering.
CI  - Copyright (c) 2020 Elsevier Ltd. All rights reserved.
FAU - Barber, Helena
AU  - Barber H
AD  - Duke University School of Medicine, 8 Searle Center Dr, Durham, NC, 27710, USA. 
      Electronic address: Helena.barber@duke.edu.
FAU - Kelly, Cambre N
AU  - Kelly CN
AD  - Duke University Department of Mechanical Engineering and Materials Science, 
      Durham, North Carolina, USA. Electronic address: cambre.kelly@duke.edu.
FAU - Nelson, Kaitlin
AU  - Nelson K
AD  - Duke University Department of Mechanical Engineering and Materials Science, 
      Durham, North Carolina, USA. Electronic address: kaitlin.nelson@duke.edu.
FAU - Gall, Ken
AU  - Gall K
AD  - Duke University Department of Mechanical Engineering and Materials Science, 
      Durham, North Carolina, USA. Electronic address: kag70@duke.edu.
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20201205
PL  - Netherlands
TA  - J Mech Behav Biomed Mater
JT  - Journal of the mechanical behavior of biomedical materials
JID - 101322406
RN  - D1JT611TNE (Titanium)
SB  - IM
MH  - Anisotropy
MH  - Porosity
MH  - *Prostheses and Implants
MH  - Tissue Engineering
MH  - Tissue Scaffolds
MH  - *Titanium
OTO - NOTNLM
OT  - Additive manufacturing
OT  - Anisotropy
OT  - Lattice structures
OT  - Powder bed fusion
OT  - Ti-6Al-4V
EDAT- 2020/12/12 06:00
MHDA- 2021/05/15 06:00
CRDT- 2020/12/11 20:15
PHST- 2020/06/08 00:00 [received]
PHST- 2020/11/06 00:00 [revised]
PHST- 2020/11/28 00:00 [accepted]
PHST- 2020/12/12 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
PHST- 2020/12/11 20:15 [entrez]
AID - S1751-6161(20)30782-7 [pii]
AID - 10.1016/j.jmbbm.2020.104243 [doi]
PST - ppublish
SO  - J Mech Behav Biomed Mater. 2021 Mar;115:104243. doi: 10.1016/j.jmbbm.2020.104243. 
      Epub 2020 Dec 5.