PMID- 33307790 OWN - NLM STAT- MEDLINE DCOM- 20211123 LR - 20220428 IS - 1724-6016 (Electronic) IS - 1120-6721 (Linking) VI - 31 IP - 6 DP - 2021 Nov TI - Femtosecond laser assisted in situ keratomileusis (FS-LASIK) yields better results than transepithelial photorefractive keratectomy (Trans-PRK) for correction of low to moderate grade myopia. PG - 2914-2922 LID - 10.1177/1120672120980346 [doi] AB - INTRODUCTION: The purpose of this study was to compare the outcomes of transepithelial photorefractive keratectomy (Trans-PRK) with femtosecond laser assisted in situ keratomileusis (FS-LASIK) for the correction of low to moderate myopia. METHODS: A retrospective cohort study design was used. The study group included patients with myopia less than -6.0 D, with or without concomitant astigmatism under 2.0 D, who were treated with FS-LASIK or Trans-PRK in 2013 through 2014. Background, clinical and outcome data were collected from the patient files. A comparison between eyes treated with FS-LASIK or Trans-PRK was performed. RESULTS: The Trans-PRK group was comprised of 1793 eyes and the FS-LASIK group of 666 eyes. Mean +/- SD spherical equivalent (SE) refraction prior to surgery was -3.43 +/- 1.27 D in the Trans-PRK group and -3.18 +/- 1.34 D in the FS-LASIK group (p < 0.001). Efficacy index values were 0.95 +/- 0.14 in the Trans-PRK group and 0.98 +/- 0.12 in the FS-LASIK group (p < 0.001), and corresponding safety index values were 0.96 +/- 0.13 and 0.99 +/- 0.12 (p < 0.001). Distance from target refraction was 0.45 +/- 0.42 D in Trans-PRK group and 0.43 +/- 0.38 D in the FS-LASIK group (p = 0.537); 71.6% and 74.2% of eyes were within +/-0.5 D of attempted correction, respectively (p = 0.193). CONCLUSIONS: Both Trans-PRK and FS-LASIK demonstrated excellent results, mostly comparable with the current literature. FS-LASIK achieved better results than Trans-PRK surgery in the efficacy and safety parameters. FAU - Gershoni, Assaf AU - Gershoni A AD - Assuta Optic Laser Center, Assuta Medical Center, Tel Aviv, Israel. AD - Department of Ophthalmology, Rabin Medical Center - Beilinson Hospital, Petah Tikva, Israel. AD - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. FAU - Reitblat, Olga AU - Reitblat O AUID- ORCID: 0000-0002-8417-4440 AD - Department of Ophthalmology, Rabin Medical Center - Beilinson Hospital, Petah Tikva, Israel. AD - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. FAU - Mimouni, Michael AU - Mimouni M AUID- ORCID: 0000-0002-4661-0993 AD - Department of Ophthalmology, Rambam Health Care Campus, Haifa, Israel. FAU - Livny, Eitan AU - Livny E AUID- ORCID: 0000-0002-3398-5905 AD - Assuta Optic Laser Center, Assuta Medical Center, Tel Aviv, Israel. AD - Department of Ophthalmology, Rabin Medical Center - Beilinson Hospital, Petah Tikva, Israel. AD - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. FAU - Nahum, Yoav AU - Nahum Y AUID- ORCID: 0000-0002-0246-4787 AD - Assuta Optic Laser Center, Assuta Medical Center, Tel Aviv, Israel. AD - Department of Ophthalmology, Rabin Medical Center - Beilinson Hospital, Petah Tikva, Israel. AD - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. FAU - Bahar, Irit AU - Bahar I AUID- ORCID: 0000-0003-2008-0717 AD - Assuta Optic Laser Center, Assuta Medical Center, Tel Aviv, Israel. AD - Department of Ophthalmology, Rabin Medical Center - Beilinson Hospital, Petah Tikva, Israel. AD - Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. LA - eng PT - Journal Article DEP - 20201214 PL - United States TA - Eur J Ophthalmol JT - European journal of ophthalmology JID - 9110772 SB - IM MH - Humans MH - *Keratomileusis, Laser In Situ MH - Lasers, Excimer/therapeutic use MH - *Myopia/surgery MH - *Photorefractive Keratectomy MH - Refraction, Ocular MH - Retrospective Studies MH - Treatment Outcome MH - Visual Acuity OTO - NOTNLM OT - Corneal procedures for myopia OT - complications of refractive surgery OT - corneal optics OT - laser biophysics OT - optics/refraction/instruments OT - refractive surgery EDAT- 2020/12/15 06:00 MHDA- 2021/11/24 06:00 CRDT- 2020/12/14 09:48 PHST- 2020/12/15 06:00 [pubmed] PHST- 2021/11/24 06:00 [medline] PHST- 2020/12/14 09:48 [entrez] AID - 10.1177/1120672120980346 [doi] PST - ppublish SO - Eur J Ophthalmol. 2021 Nov;31(6):2914-2922. doi: 10.1177/1120672120980346. Epub 2020 Dec 14.