PMID- 33310562
OWN - NLM
STAT- MEDLINE
DCOM- 20210310
LR  - 20210310
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 345
DP  - 2021 May 30
TI  - Latex microsphere immunochromatography for quantitative detection of 
      dexamethasone in milk and pork.
PG  - 128607
LID - S0308-8146(20)32469-9 [pii]
LID - 10.1016/j.foodchem.2020.128607 [doi]
AB  - Dexamethasone (DEX) is a synthetic long-acting glucocorticoid, which can increase 
      the risk of hypertension and diabetes if it is abused or used improperly. In this 
      study, lateral flow immunoassays (LFIA) based on black and blue latex 
      microspheres (LMs), integrated with a strip reader, was developed for 
      quantitative detection of DEX in milk and pork. The results could be achieved 
      within 15 min. The visible limits of detection (vLODs) were 0.3 ng/mL and 
      0.7 mug/kg for milk and pork, respectively. The quantitative limits of detection 
      (qLODs) were 0.047 ng/mL and 0.087 mug/kg, respectively. The recoveries ranged 
      from 80.0% to 122.8%. 20 milk and 10 pork samples were analyzed to confirm the 
      performance of the on-site application. The detection results were consistent 
      with the data from LC-MS/MS, indicating the practical reliability of our 
      established assay. The developed LMs-LFIA provides a promising technical support 
      for rapid, sensitive, and on-site detection of DEX.
CI  - Copyright (c) 2020 Elsevier Ltd. All rights reserved.
FAU - Li, Xiangmei
AU  - Li X
AD  - Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food 
      Science, South China Agricultural University, Guangzhou 510642, China.
FAU - Chen, Xiaomin
AU  - Chen X
AD  - Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food 
      Science, South China Agricultural University, Guangzhou 510642, China.
FAU - Liu, Zhiwei
AU  - Liu Z
AD  - Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food 
      Science, South China Agricultural University, Guangzhou 510642, China.
FAU - Wang, Jin
AU  - Wang J
AD  - Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food 
      Science, South China Agricultural University, Guangzhou 510642, China.
FAU - Hua, Qicheng
AU  - Hua Q
AD  - Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food 
      Science, South China Agricultural University, Guangzhou 510642, China.
FAU - Liang, Jinxuan
AU  - Liang J
AD  - Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food 
      Science, South China Agricultural University, Guangzhou 510642, China.
FAU - Shen, Xing
AU  - Shen X
AD  - Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food 
      Science, South China Agricultural University, Guangzhou 510642, China.
FAU - Xu, Zhenlin
AU  - Xu Z
AD  - Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food 
      Science, South China Agricultural University, Guangzhou 510642, China.
FAU - Lei, Hongtao
AU  - Lei H
AD  - Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food 
      Science, South China Agricultural University, Guangzhou 510642, China. Electronic 
      address: hongtao@scau.edu.cn.
FAU - Sun, Yuanming
AU  - Sun Y
AD  - Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food 
      Science, South China Agricultural University, Guangzhou 510642, China. Electronic 
      address: gzsyming@163.com.
LA  - eng
PT  - Journal Article
DEP - 20201112
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 0 (Latex)
RN  - 7S5I7G3JQL (Dexamethasone)
SB  - IM
MH  - Animals
MH  - Chromatography, Affinity/*methods
MH  - Chromatography, Liquid
MH  - Dexamethasone/*analysis
MH  - Food Contamination/*analysis
MH  - Latex/*chemistry
MH  - Limit of Detection
MH  - *Microspheres
MH  - Milk/*chemistry
MH  - Pork Meat/*analysis
MH  - Reproducibility of Results
MH  - Swine
OTO - NOTNLM
OT  - Dexamethasone
OT  - Lateral flow immunoassay
OT  - Latex microspheres
OT  - Milk
OT  - Pork
EDAT- 2020/12/15 06:00
MHDA- 2021/03/11 06:00
CRDT- 2020/12/14 10:38
PHST- 2020/03/11 00:00 [received]
PHST- 2020/10/11 00:00 [revised]
PHST- 2020/11/07 00:00 [accepted]
PHST- 2020/12/15 06:00 [pubmed]
PHST- 2021/03/11 06:00 [medline]
PHST- 2020/12/14 10:38 [entrez]
AID - S0308-8146(20)32469-9 [pii]
AID - 10.1016/j.foodchem.2020.128607 [doi]
PST - ppublish
SO  - Food Chem. 2021 May 30;345:128607. doi: 10.1016/j.foodchem.2020.128607. Epub 2020 
      Nov 12.