PMID- 33312245
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201216
IS  - 1841-9038 (Print)
IS  - 2069-6116 (Electronic)
IS  - 1841-9038 (Linking)
VI  - 15
IP  - 3
DP  - 2020 Sep
TI  - Algorithm of Medical-Surgical Treatment in the Peripheral Arterial Disease of the 
      Diabetic Patient.
PG  - 310-317
LID - 10.26574/maedica.2020.15.3.310 [doi]
AB  - Introduction: We live in a society with a growing number of diabetics. That is 
      why the number of diabetic patients with peripheral arterial disease is 
      expanding, as is the number of cases of chronic ischemia, which threatens limb 
      viability, or chronic limb-threatening ischemia (CLTI). The appearance of 
      diabetic foot ulcers with an ischemic component represents the maximum risk of 
      amputation in the absence of a firm and rapid revascularization intervention. In 
      our study, we aim at early detection of patients who need infusion treatment 
      immediately after surgical revascularization. Materials and methods: This is a 
      six-year retrospective study of 115 patients with infrainguinal occlusive disease 
      and CLTI. All subjects were classified according to the WIfI system before and 
      after revascularization. We made a score based on the postoperative clinical 
      evolution in the first three days in order to have an objective image of patients 
      who received infusion treatment with PG E1. Results: All patients included in our 
      study had diabetes. They were divided into two groups, one comprising 86 patients 
      who underwent exclusively surgical treatment, and the other comprising 29 
      patients, who received a combined surgical and medical treatment. We showed that 
      subjects who had a low postoperative score and received infusion treatment had a 
      higher rate of limb rescue in the first year. Conclusions: In diabetic patients 
      with infrainguinal occlusive disease who were treated in the Clinic, without the 
      possibility of endovascular or hybrid interventions, the combination of infusion 
      treatment with PG E1 after surgical revascularization led to a higher rate of 
      limb rescue and healing of ischemic trophic lesions after one year.
FAU - Neagu, Cristina
AU  - Neagu C
AD  - Diabetic Foot Compartment, "I. Cantacuzino" Clinical Hospital, Bucharest, 
      Romania.
FAU - Doran, Horia
AU  - Doran H
AD  - 1st General Surgery Clinique, "I. Cantacuzino" Clinical Hospital, Bucharest, 
      Romania.
FAU - Buzea, Alexandra
AU  - Buzea A
AD  - Ponderas Academic Hospital, Bucharest, Romania.
FAU - Agache, Alexandra
AU  - Agache A
AD  - 1st General Surgery Clinique, "I. Cantacuzino" Clinical Hospital, Bucharest, 
      Romania.
FAU - Georgescu, Dragos
AU  - Georgescu D
AD  - 1st General Surgery Clinique, "I. Cantacuzino" Clinical Hospital, Bucharest, 
      Romania.
FAU - Patrascu, Traian
AU  - Patrascu T
AD  - 1st General Surgery Clinique, "I. Cantacuzino" Clinical Hospital, Bucharest, 
      Romania.
LA  - eng
PT  - Editorial
PL  - Romania
TA  - Maedica (Bucur)
JT  - Maedica
JID - 101526930
PMC - PMC7726507
EDAT- 2020/12/15 06:00
MHDA- 2020/12/15 06:01
PMCR- 2020/09/01
CRDT- 2020/12/14 10:56
PHST- 2020/12/14 10:56 [entrez]
PHST- 2020/12/15 06:00 [pubmed]
PHST- 2020/12/15 06:01 [medline]
PHST- 2020/09/01 00:00 [pmc-release]
AID - 10.26574/maedica.2020.15.3.310 [doi]
PST - ppublish
SO  - Maedica (Bucur). 2020 Sep;15(3):310-317. doi: 10.26574/maedica.2020.15.3.310.