PMID- 33313838
OWN - NLM
STAT- MEDLINE
DCOM- 20210629
LR  - 20231108
IS  - 1462-0332 (Electronic)
IS  - 1462-0324 (Print)
IS  - 1462-0324 (Linking)
VI  - 60
IP  - 5
DP  - 2021 May 14
TI  - A comparison of physical function instruments in psoriatic arthritis: HAQ-DI vs 
      MDHAQ vs PROMIS10 global physical health.
PG  - 2307-2316
LID - 10.1093/rheumatology/keaa591 [doi]
AB  - OBJECTIVES: Physical function is a core outcome in PsA. We examined the construct 
      validity and responsiveness of three commonly used instruments to assess physical 
      function in PsA: HAQ disability index (HAQ-DI), MultiDimensional HAQ (MDHAQ) and 
      the Patient-Reported Outcomes Measurement Information System (PROMIS(R)) Global-10. 
      METHODS: Between 2016 and 2019, patients with PsA were enrolled in the Psoriatic 
      Arthritis Research Consortium longitudinal cohort study in the USA. Correlations 
      were calculated at baseline and among change scores using Spearman's correlation 
      coefficient. Standardized response means were calculated. Agreement with the 20% 
      improvement cut-off was used to determine the potential effect of using MDHAQ or 
      the PROMIS Global-10 physical health (GPH) subscore in place of HAQ-DI when 
      assessing the ACR20. RESULTS: A total of 274 patients were included in the 
      analysis. The mean age of patients was 49 years and 51% were male. At baseline, 
      the mean HAQ-DI was 0.6 (s.d. 0.6; range 0-3), the mean MDHAQ was 1.8 (s.d. 1.6; 
      range 0-10) and the mean GPH T-score was 43.4 (s.d. 9.3; range 0-100). All three 
      instruments were strongly correlated at baseline (rho 0.75-0.85). Change scores 
      were moderately correlated (rho 0.42-0.71). Among therapy initiators, the mean 
      change between two visits in HAQ-DI, MDHAQ and GPH was -0.1 (s.d. 0.4), -0.2 
      (s.d. 1.2) and 2.5 (s.d. 6.1), respectively. The standardized response means were 
      0.18, 0.16 and 0.41, respectively. CONCLUSION: The three instruments tested are 
      not directly interchangeable but have overall similar levels of responsiveness.
CI  - (c) The Author(s) 2020. Published by Oxford University Press on behalf of the 
      British Society for Rheumatology. All rights reserved. For permissions, please 
      email: journals.permissions@oup.com.
FAU - Wan, Marilyn T
AU  - Wan MT
AD  - Department of Dermatology.
AD  - Division of Rheumatology, University of Pennsylvania Perelman School of Medicine, 
      Philadelphia, PA.
FAU - Walsh, Jessica A
AU  - Walsh JA
AD  - Division of Rheumatology, University of Utah.
FAU - Craig, Ethan T
AU  - Craig ET
AD  - Division of Rheumatology, University of Pennsylvania Perelman School of Medicine, 
      Philadelphia, PA.
FAU - Husni, M Elaine
AU  - Husni ME
AD  - Division of Rheumatology, Cleveland Clinic, Cleveland, OH.
FAU - Scher, Jose U
AU  - Scher JU
AD  - Division of Rheumatology, New York University School of Medicine, New York, NY, 
      USA.
FAU - Reddy, Soumya M
AU  - Reddy SM
AD  - Division of Rheumatology, New York University School of Medicine, New York, NY, 
      USA.
FAU - Leung, Ying-Ying
AU  - Leung YY
AD  - Department of Rheumatology & Immunology, Singapore General Hospital, Singapore, 
      Singapore.
FAU - Ogdie, Alexis
AU  - Ogdie A
AUID- ORCID: 0000-0002-4639-0775
AD  - Division of Rheumatology, University of Pennsylvania Perelman School of Medicine, 
      Philadelphia, PA.
LA  - eng
GR  - R01 AR072363/AR/NIAMS NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - England
TA  - Rheumatology (Oxford)
JT  - Rheumatology (Oxford, England)
JID - 100883501
SB  - IM
MH  - *Activities of Daily Living
MH  - Adult
MH  - Arthritis, Psoriatic/diagnosis/*physiopathology
MH  - *Disability Evaluation
MH  - Female
MH  - Health Status
MH  - Health Status Indicators
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Reported Outcome Measures
MH  - Reproducibility of Results
MH  - Severity of Illness Index
PMC - PMC8599834
OTO - NOTNLM
OT  - PsA
OT  - patient-reported outcomes
EDAT- 2020/12/15 06:00
MHDA- 2021/06/30 06:00
PMCR- 2020/12/14
CRDT- 2020/12/14 11:03
PHST- 2020/04/27 00:00 [received]
PHST- 2020/07/01 00:00 [revised]
PHST- 2020/12/15 06:00 [pubmed]
PHST- 2021/06/30 06:00 [medline]
PHST- 2020/12/14 11:03 [entrez]
PHST- 2020/12/14 00:00 [pmc-release]
AID - 6033132 [pii]
AID - keaa591 [pii]
AID - 10.1093/rheumatology/keaa591 [doi]
PST - ppublish
SO  - Rheumatology (Oxford). 2021 May 14;60(5):2307-2316. doi: 
      10.1093/rheumatology/keaa591.