PMID- 33316473 OWN - NLM STAT- MEDLINE DCOM- 20210113 LR - 20210113 IS - 1879-1298 (Electronic) IS - 0045-6535 (Linking) VI - 266 DP - 2021 Mar TI - Maternal and cord serum levels of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) among Lebanese pregnant women and predictors of exposure. PG - 129211 LID - S0045-6535(20)33408-1 [pii] LID - 10.1016/j.chemosphere.2020.129211 [doi] AB - In this study, the six indicator non-dioxin-like polychlorinated biphenyls NDL-PCBs (PCB28, PCB52, PCB101, PCB138, PCB153, PCB180), as well as four organochlorine pesticides (OCPs), hexachlorobenzene (HCB), beta-hexachlorocyclohexane (beta-HCH), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichlorethylene (DDE) were measured in 98 maternal and 49 cord sera samples of a group of Lebanese women who gave birth in three hospitals in Greater Beirut, between March and July 2018. Results showed that the levels of these persistent organic pollutants (POPs) in maternal serum were below critical limits as well as those in other countries (Tunisia, France, Portugal, Spain, Poland, Greenland, Canada, Brazil, and China). The ratios of cord serum concentrations to maternal serum concentrations of analyzed POPs were higher than 1. PCB maternal serum concentrations were found to be linked to illegal incineration (OR = 5.78; p = 0.004) as well as eggs (OR = 4.68; p = 0.027) and fruits and vegetables consumption (OR = 3.92; p = 0.016). OCP concentrations were linked to red meat and cold cuts intake (OR = 3.67-4.59; p = 0.001-0.004). While PCB levels were not correlated to newborns anthropometric measurements, OCP levels in cord serum were found to be positively linked to the birth length of newborns (p = 0.014-0.027). CI - Copyright (c) 2020 Elsevier Ltd. All rights reserved. FAU - Helou, Khalil AU - Helou K AD - Department of Nutrition, Faculty of Pharmacy, Saint-Joseph University of Beirut, Medical Sciences Campus, Damascus Road, P.O.B. 11-5076, Riad Solh Beirut, 1107 2180, Lebanon. Electronic address: khalil.helou@usj.edu.lb. FAU - Matta, Joseph AU - Matta J AD - Department of Nutrition, Faculty of Pharmacy, Saint-Joseph University of Beirut, Medical Sciences Campus, Damascus Road, P.O.B. 11-5076, Riad Solh Beirut, 1107 2180, Lebanon; Industrial Research Institute, Lebanese University Campus, Hadeth Baabda, Lebanon. Electronic address: chem@iri.org.lb. FAU - Harmouche-Karaki, Mireille AU - Harmouche-Karaki M AD - Department of Nutrition, Faculty of Pharmacy, Saint-Joseph University of Beirut, Medical Sciences Campus, Damascus Road, P.O.B. 11-5076, Riad Solh Beirut, 1107 2180, Lebanon. Electronic address: mireille.harmouche@usj.edu.lb. FAU - Sayegh, Nicole AU - Sayegh N AD - Department of Nutrition, Faculty of Pharmacy, Saint-Joseph University of Beirut, Medical Sciences Campus, Damascus Road, P.O.B. 11-5076, Riad Solh Beirut, 1107 2180, Lebanon. Electronic address: nicolsayegh@gmail.com. FAU - Younes, Hassan AU - Younes H AD - UniLaSalle University, 19 Pierre Waguet Street, 60026, Beauvais, France. Electronic address: hassan.younes@unilasalle.fr. FAU - Mahfouz, Yara AU - Mahfouz Y AD - Department of Nutrition, Faculty of Pharmacy, Saint-Joseph University of Beirut, Medical Sciences Campus, Damascus Road, P.O.B. 11-5076, Riad Solh Beirut, 1107 2180, Lebanon. Electronic address: yara.mahfouz@hotmail.com. FAU - Mahfouz, Maya AU - Mahfouz M AD - Department of Nutrition, Faculty of Pharmacy, Saint-Joseph University of Beirut, Medical Sciences Campus, Damascus Road, P.O.B. 11-5076, Riad Solh Beirut, 1107 2180, Lebanon. Electronic address: mzmahfouz5@hotmail.com. FAU - Karake, Sara AU - Karake S AD - Department of Nutrition, Faculty of Pharmacy, Saint-Joseph University of Beirut, Medical Sciences Campus, Damascus Road, P.O.B. 11-5076, Riad Solh Beirut, 1107 2180, Lebanon. Electronic address: sarakarake27@gmail.com. FAU - Finan, Ramzi AU - Finan R AD - Lebanese Society of Obstetrics and Gynecology, Adliye, Beit El- Tabib - 3rd Floor, Beirut, Lebanon; Faculty of Medicine, Saint-Joseph University of Beirut, Medical Sciences Campus, Damascus Road, Beirut, Lebanon; Hotel-Dieu de France, Saint-Joseph University of Beirut Hospital, Blvd Alfred Naccache, P.O.B.: 166830, Beirut, Lebanon. Electronic address: ramzifinan@hotmail.com. FAU - Abi-Tayeh, Georges AU - Abi-Tayeh G AD - Faculty of Medicine, Saint-Joseph University of Beirut, Medical Sciences Campus, Damascus Road, Beirut, Lebanon; Hotel-Dieu de France, Saint-Joseph University of Beirut Hospital, Blvd Alfred Naccache, P.O.B.: 166830, Beirut, Lebanon; Lebanese Fertility Society, Adliye, Beit El- Tabib, Beirut, Lebanon. Electronic address: georges.abitayeh@gmail.com. FAU - Narbonne, Jean-Francois AU - Narbonne JF AD - Honorary Professor, University of Bordeaux, France. Electronic address: narbonne.jf@gmail.com. LA - eng PT - Journal Article DEP - 20201205 PL - England TA - Chemosphere JT - Chemosphere JID - 0320657 RN - 0 (Environmental Pollutants) RN - 0 (Hydrocarbons, Chlorinated) RN - 0 (Pesticides) RN - DFC2HB4I0K (Polychlorinated Biphenyls) SB - IM MH - Brazil MH - Canada MH - China MH - Environmental Monitoring MH - *Environmental Pollutants/analysis MH - Female MH - France MH - Greenland MH - Humans MH - *Hydrocarbons, Chlorinated/analysis MH - Infant, Newborn MH - *Pesticides/analysis MH - Poland MH - *Polychlorinated Biphenyls/analysis MH - Portugal MH - Pregnancy MH - Pregnant Women MH - Spain MH - Tunisia OTO - NOTNLM OT - Birth outcomes OT - Exposure predictors OT - Human biomonitoring OT - Persistent organic pollutants (POPs) OT - Pregnant women OT - Serum COIS- Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2020/12/15 06:00 MHDA- 2021/01/14 06:00 CRDT- 2020/12/14 20:09 PHST- 2020/06/30 00:00 [received] PHST- 2020/11/10 00:00 [revised] PHST- 2020/12/02 00:00 [accepted] PHST- 2020/12/15 06:00 [pubmed] PHST- 2021/01/14 06:00 [medline] PHST- 2020/12/14 20:09 [entrez] AID - S0045-6535(20)33408-1 [pii] AID - 10.1016/j.chemosphere.2020.129211 [doi] PST - ppublish SO - Chemosphere. 2021 Mar;266:129211. doi: 10.1016/j.chemosphere.2020.129211. Epub 2020 Dec 5.