PMID- 33317139
OWN - NLM
STAT- MEDLINE
DCOM- 20210907
LR  - 20240330
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 12
IP  - 12
DP  - 2020 Dec 9
TI  - Effects of Multi-Ingredient Preworkout Supplementation across a Five-Day 
      Resistance and Endurance Training Microcycle in Middle-Aged Adults.
LID - 10.3390/nu12123778 [doi]
LID - 3778
AB  - Preworkout multi-ingredient admixtures are used to maximise exercise performance. 
      The present double-blind, cross-over study compared the acute effects of 
      ingesting a preworkout multi-ingredient (PREW) admixture vs. carbohydrate (CHO) 
      over a week (microcycle) comprising three resistance training (RT) workouts 
      alternated with two 30-min low-intensity endurance sessions (END) on RT volume 
      (kg lifted) and END substrate oxidation. Additionally, postworkout decreases of 
      muscle function and subjective responses were analysed. Following a baseline 
      assessment, fourteen recreationally trained, middle-aged adults (seven females, 
      48.8 +/- 4.7 years old) completed two identical microcycles separated by a two-week 
      washout period while receiving either PREW or CHO (15 min prior to workout). The 
      RT volume, per session (SVOL) and for the entire week (WVOL), was calculated. 
      Fatty acid oxidation (FAO) during 30-min cycling corresponding to their 
      individually determined maximal fat oxidation was measured using expired gasses 
      and indirect calorimetry. Assessments of performance and tensiomyography were 
      conducted within 20 min after each RT. Higher (p = 0.001) SVOL and WVOL along 
      with a larger proportion of FAO (p = 0.05) during the second END workout were 
      determined under the PREW treatment. No other statistically significant 
      differences were observed between conditions. Compared to CHO, a preworkout 
      multi-ingredient appears to increase resistance volume and favour fat oxidation 
      during low-intensity endurance exercises.
FAU - Puente-Fernandez, Joel
AU  - Puente-Fernandez J
AD  - Institute for Lifecourse Development, School of Human Sciences, Centre for 
      Chronic Illness and Ageing, University of Greenwich, Eltham SE9 2TB, UK.
FAU - Seijo, Marcos
AU  - Seijo M
AD  - Institute for Lifecourse Development, School of Human Sciences, Centre for 
      Chronic Illness and Ageing, University of Greenwich, Eltham SE9 2TB, UK.
FAU - Larumbe-Zabala, Eneko
AU  - Larumbe-Zabala E
AD  - School of Doctorate and Research, European University of Madrid, 28670 
      Villaviciosa de Odon, Spain.
FAU - Jimenez, Alfonso
AU  - Jimenez A
AUID- ORCID: 0000-0001-5295-9668
AD  - Advanced Well-Being Research Centre, Sheffield Hallam University, Sheffield S1 
      1WB, UK.
AD  - Observatory of Healthy and Active Living of Spain Active Foundation, Centre for 
      Sport Studies, King Juan Carlos University, 28942 Madrid, Spain.
AD  - GO Fit LAB, Ingesport, 28108 Madrid, Spain.
FAU - Liguori, Gary
AU  - Liguori G
AD  - College of Health Sciences, University of Rhode Island, Kingston, RI 02881, USA.
FAU - Rossato, Claire J L
AU  - Rossato CJL
AD  - Institute for Lifecourse Development, School of Human Sciences, Centre for 
      Chronic Illness and Ageing, University of Greenwich, Eltham SE9 2TB, UK.
FAU - Mayo, Xian
AU  - Mayo X
AUID- ORCID: 0000-0002-4143-701X
AD  - GO Fit LAB, Ingesport, 28108 Madrid, Spain.
FAU - Naclerio, Fernando
AU  - Naclerio F
AUID- ORCID: 0000-0001-7405-4894
AD  - Institute for Lifecourse Development, School of Human Sciences, Centre for 
      Chronic Illness and Ageing, University of Greenwich, Eltham SE9 2TB, UK.
LA  - eng
GR  - G208/GO-Fit/
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20201209
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
SB  - IM
MH  - Calorimetry, Indirect
MH  - Cross-Over Studies
MH  - *Dietary Supplements
MH  - Double-Blind Method
MH  - Endurance Training/*methods
MH  - Female
MH  - Humans
MH  - Lipid Metabolism/*drug effects/physiology
MH  - Male
MH  - Middle Aged
MH  - Resistance Training/*methods
MH  - Sports Nutritional Physiological Phenomena/*drug effects/physiology
PMC - PMC7764411
OTO - NOTNLM
OT  - dietary supplements
OT  - multi-nutrient
OT  - performance
OT  - preworkout supplement
OT  - tensiomyography
COIS- The results of the current study are presented clearly, honestly, and without 
      fabrication, falsification, or inappropriate data manipulation. The authors 
      declare that they have no conflicts of interest relevant to the content of this 
      manuscript.
EDAT- 2020/12/16 06:00
MHDA- 2021/09/08 06:00
PMCR- 2020/12/09
CRDT- 2020/12/15 01:04
PHST- 2020/11/19 00:00 [received]
PHST- 2020/12/04 00:00 [revised]
PHST- 2020/12/06 00:00 [accepted]
PHST- 2020/12/15 01:04 [entrez]
PHST- 2020/12/16 06:00 [pubmed]
PHST- 2021/09/08 06:00 [medline]
PHST- 2020/12/09 00:00 [pmc-release]
AID - nu12123778 [pii]
AID - nutrients-12-03778 [pii]
AID - 10.3390/nu12123778 [doi]
PST - epublish
SO  - Nutrients. 2020 Dec 9;12(12):3778. doi: 10.3390/nu12123778.