PMID- 33321001
OWN - NLM
STAT- MEDLINE
DCOM- 20211213
LR  - 20211214
IS  - 1749-4486 (Electronic)
IS  - 1749-4478 (Linking)
VI  - 46
IP  - 2
DP  - 2021 Mar
TI  - Prognostic value of the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte 
      ratio and systemic immune-inflammation index in patients with laryngeal squamous 
      cell carcinoma.
PG  - 395-405
LID - 10.1111/coa.13689 [doi]
AB  - OBJECTIVES: We aimed to determine the prognostic value of the 
      neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and 
      systemic immune-inflammation index (SII) in patients with laryngeal squamous cell 
      carcinoma (LSCC). DESIGN AND SETTING: A retrospective analysis of patients with 
      LSCC was conducted in our hospitals. Clinical information, including age, sex, 
      TNM classification and other demographic and clinical data, was acquired and 
      analysed. Progression-free survival (PFS) and overall survival (OS) were 
      calculated and compared using the Kaplan-Meier method and log-rank test. 
      PARTICIPANTS: A total of 147 patients with LSCC were included. RESULTS: According 
      to the receiver operating characteristic (ROC) curve, the optimal cut-off points 
      for NLR, PLR and SII were 1.88, 117.36 and 517.64. The analysis revealed NLR, PLR 
      and SII to be independent predictors for OS and PFS (P < .05). CONCLUSIONS: 
      Preoperative NLR, PLR and SII are promising prognostic predictors for patients 
      with LSCC.
CI  - (c) 2020 John Wiley & Sons Ltd.
FAU - Li, Zhilin
AU  - Li Z
AUID- ORCID: 0000-0003-4047-940X
AD  - Department of Oral and Maxillofacial & Head and Neck Oncology, Beijing 
      Stomatological Hospital, Capital Medical University, Beijing, China.
AD  - Department of Head and Neck Oncology, Shanxi Provincial Cancer Hospital, and 
      Affiliated Cancer Hospital of Shanxi Medical University, Taiyuan, China.
FAU - Qu, Yi
AU  - Qu Y
AD  - Department of Oral and Maxillofacial & Head and Neck Oncology, Beijing 
      Stomatological Hospital, Capital Medical University, Beijing, China.
FAU - Yang, Yang
AU  - Yang Y
AD  - Department of Oral and Maxillofacial & Head and Neck Oncology, Beijing 
      Stomatological Hospital, Capital Medical University, Beijing, China.
FAU - An, Wei
AU  - An W
AD  - Department of Oral and Maxillofacial & Head and Neck Oncology, Beijing 
      Stomatological Hospital, Capital Medical University, Beijing, China.
FAU - Li, Shaoqing
AU  - Li S
AD  - Department of Oral and Maxillofacial & Head and Neck Oncology, Beijing 
      Stomatological Hospital, Capital Medical University, Beijing, China.
FAU - Wang, Bin
AU  - Wang B
AD  - Department of Oral and Maxillofacial & Head and Neck Oncology, Beijing 
      Stomatological Hospital, Capital Medical University, Beijing, China.
FAU - He, Ying
AU  - He Y
AD  - Department of Oral and Maxillofacial & Head and Neck Oncology, Beijing 
      Stomatological Hospital, Capital Medical University, Beijing, China.
FAU - Li, Jing
AU  - Li J
AD  - Department of Oral and Maxillofacial & Head and Neck Oncology, Beijing 
      Stomatological Hospital, Capital Medical University, Beijing, China.
FAU - Shao, Qi
AU  - Shao Q
AD  - Department of Oral and Maxillofacial & Head and Neck Oncology, Beijing 
      Stomatological Hospital, Capital Medical University, Beijing, China.
FAU - Qin, Lizheng
AU  - Qin L
AD  - Department of Oral and Maxillofacial & Head and Neck Oncology, Beijing 
      Stomatological Hospital, Capital Medical University, Beijing, China.
LA  - eng
PT  - Journal Article
DEP - 20201227
PL  - England
TA  - Clin Otolaryngol
JT  - Clinical otolaryngology : official journal of ENT-UK ; official journal of 
      Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
JID - 101247023
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Platelets/*immunology
MH  - Carcinoma, Squamous Cell/*immunology/mortality
MH  - Female
MH  - Humans
MH  - Inflammation/immunology
MH  - Laryngeal Neoplasms/*immunology/mortality
MH  - Lymphocytes/*immunology
MH  - Male
MH  - Middle Aged
MH  - Neutrophils/*immunology
MH  - Prognosis
MH  - Retrospective Studies
MH  - Survival Analysis
OTO - NOTNLM
OT  - laryngeal squamous cell carcinoma
OT  - neutrophil-to-lymphocyte ratio
OT  - platelet-to-lymphocyte ratio
OT  - prognosis
OT  - systemic immune-inflammation index
EDAT- 2020/12/16 06:00
MHDA- 2021/12/15 06:00
CRDT- 2020/12/15 17:14
PHST- 2020/05/22 00:00 [received]
PHST- 2020/08/06 00:00 [revised]
PHST- 2020/11/29 00:00 [accepted]
PHST- 2020/12/16 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
PHST- 2020/12/15 17:14 [entrez]
AID - 10.1111/coa.13689 [doi]
PST - ppublish
SO  - Clin Otolaryngol. 2021 Mar;46(2):395-405. doi: 10.1111/coa.13689. Epub 2020 Dec 
      27.