PMID- 33329354
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201218
IS  - 1664-2295 (Print)
IS  - 1664-2295 (Electronic)
IS  - 1664-2295 (Linking)
VI  - 11
DP  - 2020
TI  - Hemodynamic Effect of the Last Finishing Coils in Packing the Aneurysm Neck.
PG  - 598412
LID - 10.3389/fneur.2020.598412 [doi]
LID - 598412
AB  - Background: Using the finishing coils to densely pack the aneurysm neck is 
      necessary. However, the exact hemodynamic effect of finishing coils in packing 
      the aneurysm neck is unknown. Objective: To evaluate the hemodynamic 
      characteristics of finishing coils to densely pack the aneurysm neck, using 
      finite element method simulation. Methods: A computational study was performed 
      based on a 44-year-old female patient with an unruptured wide-necked 
      carotid-ophthalmic artery aneurysm treated with low-profile visualized 
      intraluminal support stent-assisted coil embolization. Four computational fluid 
      dynamics models including pre-treatment, post-stenting, common stent-assisted 
      coil embolization (SACE), and common SACE with finishing coils were evaluated 
      qualitatively and quantitatively. Results: Compared with the baseline of 
      pretreatment model (100%), sac-averaged velocity in post-stenting, common SACE, 
      and common SACE with finishing coil models decreased to 95.68%, 24.38%, and 
      13.20%, respectively; high flow volume (>0.1 m/s) around the aneurysm neck 
      decreased to 92.19%, 9.59%, and 5.57%, respectively; and mean wall shear stress 
      increased or decreased to 107%, 25.94%, and 23.89%, respectively. Conclusion: 
      Finishing coils to densely pack the aneurysm neck can generate favorable 
      hemodynamic modifications, which may decrease the recurrence.
CI  - Copyright (c) 2020 Wan, Lu, Huang, Ge, Jiang, Li, Leng, Xiang and Zhang.
FAU - Wan, Hailin
AU  - Wan H
AD  - Huashan Hospital, Fudan University, Shanghai, China.
FAU - Lu, Gang
AU  - Lu G
AD  - Huashan Hospital, Fudan University, Shanghai, China.
FAU - Huang, Lei
AU  - Huang L
AD  - Huashan Hospital, Fudan University, Shanghai, China.
FAU - Ge, Liang
AU  - Ge L
AD  - Huashan Hospital, Fudan University, Shanghai, China.
FAU - Jiang, Yeqing
AU  - Jiang Y
AD  - Huashan Hospital, Fudan University, Shanghai, China.
FAU - Li, Gaohui
AU  - Li G
AD  - ArteryFlow Technology Co., Ltd, Hangzhou, China.
FAU - Leng, Xiaochang
AU  - Leng X
AD  - ArteryFlow Technology Co., Ltd, Hangzhou, China.
FAU - Xiang, Jianping
AU  - Xiang J
AD  - ArteryFlow Technology Co., Ltd, Hangzhou, China.
FAU - Zhang, Xiaolong
AU  - Zhang X
AD  - Huashan Hospital, Fudan University, Shanghai, China.
LA  - eng
PT  - Journal Article
DEP - 20201120
PL  - Switzerland
TA  - Front Neurol
JT  - Frontiers in neurology
JID - 101546899
PMC - PMC7714910
OTO - NOTNLM
OT  - coiling
OT  - hemodynamics
OT  - intracranial aneurysms
OT  - recurrence
OT  - stent
EDAT- 2020/12/18 06:00
MHDA- 2020/12/18 06:01
PMCR- 2020/11/20
CRDT- 2020/12/17 05:49
PHST- 2020/08/24 00:00 [received]
PHST- 2020/10/15 00:00 [accepted]
PHST- 2020/12/17 05:49 [entrez]
PHST- 2020/12/18 06:00 [pubmed]
PHST- 2020/12/18 06:01 [medline]
PHST- 2020/11/20 00:00 [pmc-release]
AID - 10.3389/fneur.2020.598412 [doi]
PST - epublish
SO  - Front Neurol. 2020 Nov 20;11:598412. doi: 10.3389/fneur.2020.598412. eCollection 
      2020.