PMID- 33331703
OWN - NLM
STAT- MEDLINE
DCOM- 20201218
LR  - 20201218
IS  - 0370-629X (Print)
IS  - 0370-629X (Linking)
VI  - 75
IP  - 12
DP  - 2020 Dec
TI  - [Iron deficiency in adults : to understand what biological evaluation should be 
      carried out].
PG  - 791-796
AB  - Iron is a major mineral in the human body. It participates in various 
      metabolisms, including oxygen transport in hemoglobin. Iron deficiency (ID) is 
      characterized by a deficit in circulating iron. There are two types of ID : 1) 
      absolute ID (AID), in case of decrease in iron reserves and circulating iron, or 
      2) functional ID (FID), in case of decrease in circulating iron, while reserves 
      are preserved or increased. AID is mainly due to bleeding, usually 
      gastrointestinal, while FID is linked to the inflammatory syndrome. AID is 
      characterized by low serum ferritin and transferrin saturation (TS). Hypochromic 
      microcytic anemia is frequent. FID is characterized by elevated serum ferritin, 
      normal or low TS, and normal sTfR levels. Furthermore, C-reactive protein levels 
      are high, and there is non-regenerative non-macrocytic anemia. New biological 
      tests (serum hepcidin) may be useful in case of doubt. However, they are not yet 
      commonly used.
FAU - Manckoundia, P
AU  - Manckoundia P
AD  - Pole Personnes Agees, CHU Dijon-Bourgogne, France.
AD  - UMR Inserm/U1093 Cognition, Action, Plasticite sensorimotrice, Universite 
      Bourgogne Franche-Comte, Dijon, France.
FAU - Barben, J
AU  - Barben J
AD  - Pole Personnes Agees, CHU Dijon-Bourgogne, France.
FAU - Asgassou, S
AU  - Asgassou S
AD  - Pole Personnes Agees, CHU Dijon-Bourgogne, France.
FAU - Putot, A
AU  - Putot A
AD  - Pole Personnes Agees, CHU Dijon-Bourgogne, France.
FAU - Konate, A
AU  - Konate A
AD  - Unite de DIAGnostic et d'Orientation RApide (DIAGORA), Departement de Medecine 
      interne, CHU, Montpellier, France.
LA  - fre
PT  - Journal Article
TT  - Deficit en fer chez l'adulte : comprendre quel bilan biologique realiser.
PL  - Belgium
TA  - Rev Med Liege
JT  - Revue medicale de Liege
JID - 0404317
RN  - 0 (Biological Products)
RN  - 0 (Biomarkers)
RN  - E1UOL152H7 (Iron)
SB  - IM
MH  - Adult
MH  - *Anemia, Hypochromic
MH  - *Anemia, Iron-Deficiency/diagnosis
MH  - *Biological Products
MH  - Biomarkers
MH  - Humans
MH  - Iron
OTO - NOTNLM
OT  - Biomarkers
OT  - Iron deficiency
OT  - Iron metabolism
OT  - Anemia
EDAT- 2020/12/18 06:00
MHDA- 2020/12/19 06:00
CRDT- 2020/12/17 08:43
PHST- 2020/12/17 08:43 [entrez]
PHST- 2020/12/18 06:00 [pubmed]
PHST- 2020/12/19 06:00 [medline]
PST - ppublish
SO  - Rev Med Liege. 2020 Dec;75(12):791-796.