PMID- 33336770
OWN - NLM
STAT- MEDLINE
DCOM- 20210101
LR  - 20210101
IS  - 2284-0729 (Electronic)
IS  - 1128-3602 (Linking)
VI  - 24
IP  - 23
DP  - 2020 Dec
TI  - Containment measures established during the COVID-19 outbreak and its impact on 
      lipid profile and neutrophil to lymphocyte ratio.
PG  - 12510-12515
LID - 24047 [pii]
LID - 10.26355/eurrev_202012_24047 [doi]
AB  - OBJECTIVE: Almost all countries announced social restrictions and distancing 
      measures which could unintentionally lead to a decline in admissions to hospital 
      for acute disorders other than signs of pneumonia. We aimed to evaluate lipid 
      profile, neutrophil to lymphocyte ratio (NLR) and cardiovascular admissions to 
      the coronary care unit (CCU) of a tertiary center in Turkey during the COVID-19 
      era and to compare these results with admissions in the same time interval of the 
      previous year. MATERIALS AND METHODS: We retrospectively analyzed CCU admissions 
      due to new-onset atrial fibrillation, ST-elevation myocardial infarction, non-ST 
      elevation acute coronary syndrome (NSTEACS) and acute heart failure during the 
      COVID-19 outbreak and the same time interval of the past year. Laboratory 
      measurements including lipid profile and NLR values were retrieved from the 
      institutional digital database. RESULTS: Compared to the same time interval of 
      2019 (March-April, 2019), the number of patients admitted to the CCU with acute 
      cardiovascular disorders (atrial fibrillation, STEMI, NSTEACS and acute heart 
      failure) were lower in the COVID-19 period. The levels of NLR, total cholesterol, 
      and low-density lipoprotein (LDL) cholesterol were significantly higher and 
      high-density lipoprotein (HDL) cholesterol was significantly lower in subjects 
      admitted to the CCU during March-April 2020 compared to subjects admitted in 
      March-April 2019. CONCLUSIONS: Our findings show that subjects admitted to the 
      CCU in the COVID-19 era have an unfavorable lipid profile and elevated NLR 
      compared to those admitted in 2019. These patients appear to be at high risk for 
      future cardiovascular events.
FAU - Aladag, N
AU  - Aladag N
AD  - Van Yuzuncu Yil University, Faculty of Medicine, Department of Cardiology, Van, 
      Turkey. nesimaladag@hotmail.com.
FAU - Sipal, A
AU  - Sipal A
FAU - Atabey, R D
AU  - Atabey RD
FAU - Akbulut, T
AU  - Akbulut T
FAU - Asoglu, R
AU  - Asoglu R
FAU - Ozdemir, M
AU  - Ozdemir M
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Eur Rev Med Pharmacol Sci
JT  - European review for medical and pharmacological sciences
JID - 9717360
RN  - 0 (Cholesterol, HDL)
RN  - 0 (Cholesterol, LDL)
RN  - 97C5T2UQ7J (Cholesterol)
SB  - IM
MH  - Acute Coronary Syndrome/*blood/epidemiology
MH  - Aged
MH  - Atrial Fibrillation/*blood/epidemiology
MH  - *COVID-19
MH  - Cholesterol/blood
MH  - Cholesterol, HDL/blood
MH  - Cholesterol, LDL/blood
MH  - Cohort Studies
MH  - Communicable Disease Control
MH  - Coronary Care Units
MH  - Dyslipidemias/*blood/epidemiology
MH  - Female
MH  - Heart Failure/*blood/epidemiology
MH  - Humans
MH  - Leukocyte Count
MH  - *Lymphocyte Count
MH  - Male
MH  - Middle Aged
MH  - *Neutrophils
MH  - Retrospective Studies
MH  - SARS-CoV-2
MH  - ST Elevation Myocardial Infarction/*blood/epidemiology
MH  - Turkey/epidemiology
EDAT- 2020/12/19 06:00
MHDA- 2021/01/02 06:00
CRDT- 2020/12/18 08:37
PHST- 2020/12/18 08:37 [entrez]
PHST- 2020/12/19 06:00 [pubmed]
PHST- 2021/01/02 06:00 [medline]
AID - 24047 [pii]
AID - 10.26355/eurrev_202012_24047 [doi]
PST - ppublish
SO  - Eur Rev Med Pharmacol Sci. 2020 Dec;24(23):12510-12515. doi: 
      10.26355/eurrev_202012_24047.