PMID- 33339339
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201229
IS  - 2076-2607 (Print)
IS  - 2076-2607 (Electronic)
IS  - 2076-2607 (Linking)
VI  - 8
IP  - 12
DP  - 2020 Dec 16
TI  - Characterization of Actinomycetes Strains Isolated from the Intestinal Tract and 
      Feces of the Larvae of the Longhorn Beetle Cerambyx welensii.
LID - 10.3390/microorganisms8122013 [doi]
LID - 2013
AB  - Actinomycetes constitute a large group of Gram-positive bacteria present in 
      different habitats. One of these habitats involves the association of these 
      bacteria with insects. In this work, we have studied twenty-four actinomycetes 
      strains isolated from the intestinal tract and feces from larvae of the 
      xylophagous coleopteran Cerambyx welensii and have shown that seventeen strains 
      present hydrolytic activity of some of the following substrates: cellulose, 
      hemicellulose, starch and proteins. Fourteen of the isolates produce 
      antimicrobial molecules against the Gram-positive bacteria Micrococcus luteus. 
      Analysis of seven strains led us to identify the production of a wide number of 
      compounds including streptanoate, alpiniamide A, alteramides A and B, 
      coproporphyrin III, deferoxamine, demethylenenocardamine, dihydropicromycin, 
      nocardamine, picromycin, surugamides A, B, C, D and E, tirandamycins A and B, and 
      valinomycin. A significant number of other compounds, whose molecular formulae 
      are not included in the Dictionary of Natural Products (DNP), were also present 
      in the extracts analyzed, which opens up the possibility of identifying new 
      active antibiotics. Molecular identification of ten of the isolated bacteria 
      determined that six of them belong to the genus Streptomyces, two of them are 
      included in the genus Amycolatopsis and two in the genus Nocardiopsis.
FAU - Santamaria, Ramon I
AU  - Santamaria RI
AD  - Departamento de Microbiologia y Genetica, Instituto de Biologia Funcional y 
      Genomica (IBFG), Consejo Superior de Investigaciones Cientificas (CSIC), 
      Universidad de Salamanca, C/Zacarias Gonzalez 2, 37007 Salamanca, Spain.
FAU - Martinez-Carrasco, Ana
AU  - Martinez-Carrasco A
AD  - Departamento de Microbiologia y Genetica, Instituto de Biologia Funcional y 
      Genomica (IBFG), Consejo Superior de Investigaciones Cientificas (CSIC), 
      Universidad de Salamanca, C/Zacarias Gonzalez 2, 37007 Salamanca, Spain.
FAU - Sanchez de la Nieta, Ricardo
AU  - Sanchez de la Nieta R
AUID- ORCID: 0000-0003-2065-5023
AD  - Departamento de Microbiologia y Genetica, Instituto de Biologia Funcional y 
      Genomica (IBFG), Consejo Superior de Investigaciones Cientificas (CSIC), 
      Universidad de Salamanca, C/Zacarias Gonzalez 2, 37007 Salamanca, Spain.
FAU - Torres-Vila, Luis M
AU  - Torres-Vila LM
AD  - Servicio de Sanidad Vegetal, Consejeria de Agricultura DRPyT, Junta de 
      Extremadura, Avda. Luis Ramallo s/n, 06800 Badajoz, Spain.
FAU - Bonal, Raul
AU  - Bonal R
AUID- ORCID: 0000-0002-6084-1771
AD  - Forest Research Group, INDEHESA, Escuela de Ingenieria Forestal, Universidad de 
      Extremadura, Avda. Virgen del Puerto 2, 10600 Caceres, Spain.
FAU - Martin, Jesus
AU  - Martin J
AD  - Fundacion MEDINA, Centro de Excelencia en Investigacion de Medicamentos 
      Innovadores en Andalucia, Avda. del Conocimiento 34, 18016 Granada, Spain.
FAU - Tormo, Ruben
AU  - Tormo R
AUID- ORCID: 0000-0001-6984-2941
AD  - Fundacion MEDINA, Centro de Excelencia en Investigacion de Medicamentos 
      Innovadores en Andalucia, Avda. del Conocimiento 34, 18016 Granada, Spain.
FAU - Reyes, Fernando
AU  - Reyes F
AUID- ORCID: 0000-0003-1607-5106
AD  - Fundacion MEDINA, Centro de Excelencia en Investigacion de Medicamentos 
      Innovadores en Andalucia, Avda. del Conocimiento 34, 18016 Granada, Spain.
FAU - Genilloud, Olga
AU  - Genilloud O
AUID- ORCID: 0000-0002-4202-1219
AD  - Fundacion MEDINA, Centro de Excelencia en Investigacion de Medicamentos 
      Innovadores en Andalucia, Avda. del Conocimiento 34, 18016 Granada, Spain.
FAU - Diaz, Margarita
AU  - Diaz M
AUID- ORCID: 0000-0003-4286-1506
AD  - Departamento de Microbiologia y Genetica, Instituto de Biologia Funcional y 
      Genomica (IBFG), Consejo Superior de Investigaciones Cientificas (CSIC), 
      Universidad de Salamanca, C/Zacarias Gonzalez 2, 37007 Salamanca, Spain.
LA  - eng
GR  - BIO2015-66958-R PID2019-107716RB-I00/MINECO/FEDER/
GR  - SA036G19 CLU-2017-03/14-20/Regional Government of Castile and Leon/FEDER/
PT  - Journal Article
DEP - 20201216
PL  - Switzerland
TA  - Microorganisms
JT  - Microorganisms
JID - 101625893
PMC - PMC7766275
OTO - NOTNLM
OT  - Amycolatopsis
OT  - Cerambyx
OT  - Nocardiopsis
OT  - Streptomyces
OT  - actinomycetes
OT  - antibiotic production
OT  - hydrolytic enzymes
COIS- The authors declare no conflict of interest and the funding bodies had no role in 
      designing the study, in the collection, analyses or interpretation of the data, 
      in writing the manuscript or in the decision to publish the results.
EDAT- 2020/12/20 06:00
MHDA- 2020/12/20 06:01
PMCR- 2020/12/16
CRDT- 2020/12/19 01:02
PHST- 2020/11/23 00:00 [received]
PHST- 2020/12/04 00:00 [revised]
PHST- 2020/12/14 00:00 [accepted]
PHST- 2020/12/19 01:02 [entrez]
PHST- 2020/12/20 06:00 [pubmed]
PHST- 2020/12/20 06:01 [medline]
PHST- 2020/12/16 00:00 [pmc-release]
AID - microorganisms8122013 [pii]
AID - microorganisms-08-02013 [pii]
AID - 10.3390/microorganisms8122013 [doi]
PST - epublish
SO  - Microorganisms. 2020 Dec 16;8(12):2013. doi: 10.3390/microorganisms8122013.