PMID- 33342195
OWN - NLM
STAT- MEDLINE
DCOM- 20210901
LR  - 20210901
IS  - 2149-8709 (Electronic)
IS  - 2149-8695 (Print)
IS  - 2149-8709 (Linking)
VI  - 50
IP  - 5
DP  - 2020 Oct 30
TI  - Correlation of Visual Recovery and Increased Ellipsoid Zone Reflectivity After 
      Successful Macular Hole Surgery.
PG  - 283-287
LID - 10.4274/tjo.galenos.2020.21456 [doi]
AB  - OBJECTIVES: To assess changes in reflectivity of the retinal pigment epithelium 
      (RPE), ellipsoid zone (EZ), and external limiting membrane (ELM) on spectral 
      domain-optical coherence tomography (SD-OCT) images and the effects of 
      reflectivity changes on visual acuity improvement after vitrectomy in macular 
      hole patients. MATERIALS AND METHODS: Twenty-four eyes of 24 patients with 
      idiopathic full-thickness macular hole closed after vitrectomy were 
      retrospectively reviewed. The "plot profile" function of the medical imaging 
      software was used by a single masked physician to analyze RPE, EZ, and ELM 
      reflectivity on OCT images at postoperative 1 month and 12 months. RESULTS: 
      Absolute and relative EZ reflectivity showed highly significant increases at 
      postoperative 12 months compared to 1 month (p<0.001 and p<0.001, respectively). 
      Absolute and relative EZ reflectivity changes from postoperative month 1 to month 
      12 after macular hole surgery were significantly correlated with best corrected 
      visual acuity improvement (p=0.012 and p=0.020, respectively). CONCLUSION: EZ 
      reflectivity can be a predictor of functional and anatomical improvement after 
      macular hole surgery.
FAU - Yilmaz Tugan, Busra
AU  - Yilmaz Tugan B
AUID- ORCID: 0000-0001-6660-1608
AD  - Kocaeli University Faculty of Medicine, Department of Ophthalmology, Kocaeli, 
      Turkey.
FAU - Karabas, Levent
AU  - Karabas L
AUID- ORCID: 0000-0003-4271-4741
AD  - Kocaeli University Faculty of Medicine, Department of Ophthalmology, Kocaeli, 
      Turkey.
FAU - Yenihayat, Fatih
AU  - Yenihayat F
AUID- ORCID: 0000-0003-0872-6714
AD  - Dunyagoz Kocaeli Hospital, Clinic of Ophthalmology, Kocaeli, Turkey.
FAU - Subasi, Sevgi
AU  - Subasi S
AUID- ORCID: 0000-0002-1099-9626
AD  - Kocaeli University Faculty of Medicine, Department of Ophthalmology, Kocaeli, 
      Turkey.
FAU - Kesim, Enes
AU  - Kesim E
AUID- ORCID: 0000-0002-0083-975X
AD  - Tuzla State Hospital, Clinic of Ophthalmology, Istanbul, Turkey.
FAU - Ozkan, Berna
AU  - Ozkan B
AUID- ORCID: 0000-0002-2212-4448
AD  - Acibadem Mehmet Ali Aydinlar University Faculty of Medicine, Department of 
      Ophthalmology, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
PL  - Turkey
TA  - Turk J Ophthalmol
JT  - Turkish journal of ophthalmology
JID - 101686048
SB  - IM
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Postoperative Period
MH  - Recovery of Function/*physiology
MH  - Retinal Perforations/*physiopathology/surgery
MH  - Retinal Pigment Epithelium/*pathology
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence/methods
MH  - Treatment Outcome
MH  - *Visual Acuity
MH  - Vitrectomy/*methods
PMC - PMC7610054
OTO - NOTNLM
OT  - Absolute and relative reflectivity
OT  - ellipsoid zone reflectivity
OT  - macular hole
OT  - vitrectomy
COIS- Conflict of Interest: No conflict of interest was declared by the authors.
EDAT- 2020/12/22 06:00
MHDA- 2021/09/02 06:00
PMCR- 2020/10/01
CRDT- 2020/12/21 02:49
PHST- 2020/12/21 02:49 [entrez]
PHST- 2020/12/22 06:00 [pubmed]
PHST- 2021/09/02 06:00 [medline]
PHST- 2020/10/01 00:00 [pmc-release]
AID - 41733 [pii]
AID - 10.4274/tjo.galenos.2020.21456 [doi]
PST - ppublish
SO  - Turk J Ophthalmol. 2020 Oct 30;50(5):283-287. doi: 
      10.4274/tjo.galenos.2020.21456.