PMID- 33343066 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210330 IS - 0860-021X (Print) IS - 2083-1862 (Electronic) IS - 0860-021X (Linking) VI - 37 IP - 4 DP - 2020 Dec TI - Effect of resistance training to muscle failure vs non-failure on strength, hypertrophy and muscle architecture in trained individuals. PG - 333-341 LID - 10.5114/biolsport.2020.96317 [doi] AB - The aim of this study was to compare the effects of resistance training to muscle failure (RT-F) and non-failure (RT-NF) on muscle mass, strength and activation of trained individuals. We also compared the effects of these protocols on muscle architecture parameters. A within-subjects design was used in which 14 participants had one leg randomly assigned to RT-F and the other to RT-NF. Each leg was trained 2 days per week for 10 weeks. Vastus lateralis (VL) muscle cross-sectional area (CSA), pennation angle (PA), fascicle length (FL) and 1-repetition maximum (1-RM) were assessed at baseline (Pre) and after 20 sessions (Post). The electromyographic signal (EMG) was assessed after the training period. RT-F and RT-NF protocols showed significant and similar increases in CSA (RT-F: 13.5% and RT-NF: 18.1%; P < 0.0001), PA (RT-F: 13.7% and RT-NF: 14.4%; P < 0.0001) and FL (RT-F: 11.8% and RT-NF: 8.6%; P < 0.0001). All protocols showed significant and similar increases in leg press (RT-F: 22.3% and RT-NF: 26.7%; P < 0.0001) and leg extension (RT-F: 33.3%, P < 0.0001 and RT-NF: 33.7%; P < 0.0001) 1-RM loads. No significant differences in EMG amplitude were detected between protocols (P > 0.05). In conclusion, RT-F and RT-NF are similarly effective in promoting increases in muscle mass, PA, FL, strength and activation. CI - Copyright (c) Biology of Sport 2020. FAU - Santanielo, Natalia AU - Santanielo N AD - MUSCULAB - Laboratory of Neuromuscular Adaptations to Resistance Training, Department of Physical Education, Federal University of Sao Carlos - UFSCar, Sao Carlos, SP, Brazil. FAU - Nobrega, Sanmy R AU - Nobrega SR AD - MUSCULAB - Laboratory of Neuromuscular Adaptations to Resistance Training, Department of Physical Education, Federal University of Sao Carlos - UFSCar, Sao Carlos, SP, Brazil. FAU - Scarpelli, Maira C AU - Scarpelli MC AD - MUSCULAB - Laboratory of Neuromuscular Adaptations to Resistance Training, Department of Physical Education, Federal University of Sao Carlos - UFSCar, Sao Carlos, SP, Brazil. FAU - Alvarez, Ieda F AU - Alvarez IF AD - MUSCULAB - Laboratory of Neuromuscular Adaptations to Resistance Training, Department of Physical Education, Federal University of Sao Carlos - UFSCar, Sao Carlos, SP, Brazil. FAU - Otoboni, Gabriele B AU - Otoboni GB AD - MUSCULAB - Laboratory of Neuromuscular Adaptations to Resistance Training, Department of Physical Education, Federal University of Sao Carlos - UFSCar, Sao Carlos, SP, Brazil. FAU - Pintanel, Lucas AU - Pintanel L AD - MUSCULAB - Laboratory of Neuromuscular Adaptations to Resistance Training, Department of Physical Education, Federal University of Sao Carlos - UFSCar, Sao Carlos, SP, Brazil. FAU - Libardi, Cleiton A AU - Libardi CA AD - MUSCULAB - Laboratory of Neuromuscular Adaptations to Resistance Training, Department of Physical Education, Federal University of Sao Carlos - UFSCar, Sao Carlos, SP, Brazil. LA - eng PT - Journal Article DEP - 20200705 PL - Poland TA - Biol Sport JT - Biology of sport JID - 8700872 PMC - PMC7725035 OTO - NOTNLM OT - Electromyography OT - Fascicle length OT - Muscle fatigue OT - Muscle mass OT - Pennation angle COIS- The authors declare that they have no conflict of interest. EDAT- 2020/12/22 06:00 MHDA- 2020/12/22 06:01 PMCR- 2020/12/01 CRDT- 2020/12/21 06:02 PHST- 2020/04/11 00:00 [received] PHST- 2020/05/11 00:00 [revised] PHST- 2020/05/23 00:00 [accepted] PHST- 2020/12/21 06:02 [entrez] PHST- 2020/12/22 06:00 [pubmed] PHST- 2020/12/22 06:01 [medline] PHST- 2020/12/01 00:00 [pmc-release] AID - 96317 [pii] AID - 10.5114/biolsport.2020.96317 [doi] PST - ppublish SO - Biol Sport. 2020 Dec;37(4):333-341. doi: 10.5114/biolsport.2020.96317. Epub 2020 Jul 5.